Report Description
Protein Expression Market Outlook 2031
The Global Protein expression market size was valued at USD 3.18 Billion in 2022 and is likely reach to USD 7.11 Billion by 2031, expanding at a CAGR of 9.36% during the forecast period, 2023–2031. The growth of the market is attributed to the elderly growing population, age-related disorders, and the incidence of chronic diseases including cancer are all on the rise.
Protein expression is the process of synthesizing, modifying, and regulating proteins. Protein expression is the use of experimental tools and procedures to help in the production of proteins.
Protein expression is a biotechnological procedure for producing a specific protein, which is commonly accomplished by manipulating gene expression in an animal to produce huge amounts of recombinant genes. The method can be used to make and filter the target protein inside or outside of a cell.
Proteins made utilizing the protein expression approach can be employed in industrial operations as well as for diagnosing and treating diseases. Protein expression generates the enzymes or substrates needed for further investigation.
The advancement of genetic engineering and recombinant technology has opened countless opportunities for homogeneous protein expression and separation in academic, therapeutic, and industrial settings. Biotechnology advancements have made large-scale production and separation of recombinant proteins possible.
Market Trends, Drivers, Restraints, and Opportunities
- Rising biotechnology need and the rise of the biomedical industry is expected to propel the market growth in the coming years.
- Protein expression solutions for research and production are becoming more prominent owing to the accessibility of new and improved technologies to fulfill the demand for pharmaceuticals and biologics product makers are projected to spur the market expansion during the forecast period.
- Increasing demand for therapeutic proteins including hormones, insulin, monoclonal, vaccines, and antibodies are key factors boosting the market growth in the coming years.
- Scarcity of skilled healthcare workers as well as a lack of knowledge is estimated to hinder the market growth.
- Low R&D investment and the increased price of proteomics research possess as key factors that can impede the market expansion in the coming years.
- Rapid advancements in medical technology, improved disease diagnosis, and the expansion of healthcare in developing economies are anticipated to create significant opportunities for the market players.
Scope of Protein Expression Market Report
The report on the global protein expression market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes
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Details
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Report Title
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Protein Expression Market - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast
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Base Year
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2022
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Historic Data
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2016–2021
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Forecast Period
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2023–2031
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Segmentation
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Products (Reagents and Kits [Bacterial Expressions, Algal Expressions, Cell-free Expressions, Mammalian Expressions, Yeast Expressions, Insect Expressions, and Others], Services, and Others), Applications (Industrial, Therapeutics, and Research), End-users (Pharmaceuticals, Academics, and Biotechnology)
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Regional Scope
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Asia Pacific, North America, Latin America, Europe, and Middle East & Africa
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Report Coverage
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Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, and Trends, and Revenue Forecast
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Key Players Covered in the Report
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Becton, Dickinson & Company; Thermo Fisher Scientific Inc.; Takara Bio, Inc.; Qiagen N.V; Promega Corporation; Oxford Expression Technologies Ltd.; Synthetic Genomics Inc.; New England Biolabs, Inc.; Merck KGaA; Bio-Rad Laboratories Inc.; Agilent Technologies; and Genscript Biotech Corporation
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Protein Expression Market Segment Insights
Cell-free expressions segment is projected to account for a key market share
Based on products, the global protein expression market is divided into reagents and kits [bacterial expressions, algal expressions, cell-free expressions, mammalian expressions, yeast expressions, insect expressions, and others.
The cell-free expressions segment is expected to hold a key share of the market during the forecast period due to protein expression is done without the usage of live cells. This technology offers numerous advantages over all other protein expression methods, and it is extensively caused as a result of these advantages.
Because of the benefits of cell-free protein approaches, including enhanced pace, the capacity to produce hazardous proteins, and the simplicity of amino acid class-specific labeling, among others, the cell expression market is expected to develop.
Large screening for shortened proteins, production of proteins that are harmful to expression carriers in vivo, production of proteins containing amino acids, and insertion of post-translational changes are only a few of the uses of cell-free expression.
Protein nano-crystallography is the newest trend in cell-free expression research. This method can create and characterize stable protein microcrystals down to the atomic level.

Therapeutics segment is expected to grow at a significant pace
On the basis of applications, the market is segmented into industrial, therapeutics, and research. The therapeutics segment is expected to constitute a key share of the market in the coming years owing to the increasing prevalence of the disease, as well as increased R&D activities, which are driving this segment's rise.
Proteomics-based research is on the rise, as is the incidence of chronic diseases around the world, which explains the substantial proportion of this market.
Peptide hormones, vaccinations, therapeutic enzymes, monoclonal antibodies, antibodies, cytokines, and blood factors, are examples of therapeutic proteins that are prescribed to treat chronic diseases including diabetes, cancer, and multiple sclerosis. In the manufacture of biological drugs, these proteins have improved quality, precision, and effectiveness.
Pharmaceuticals segment is anticipated to register at a substantial CAGR
In terms of end-users, the global protein expression market is segregated into pharmaceuticals, academics, and biotechnology. The pharmaceuticals segment is expected to represent a key share of the market during the forecast period due to the increased focus on proteomics research and biologics manufacture.
Protein Expression Market Regional Outlook
United States in North America is anticipated to dominate the market
On the basis of regions, the market is classified as Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. United States in North America is anticipated to dominate the market at an impressive CAGR during the forecast period.
The regional market growth can be attributed to the factors driving the protein expression market in the United States include investment in research and development, a rise in the use of protein technology, and the region's rapidly evolving healthcare companies.
The existence of multiple enterprises in the region itself is another element pushing the protein expression market in the United States.
The market's prospects for expansion are being boosted by increased research activity in the United States pharmaceutical industry. Developments in the area of proteomics have grown the industry even further in the United States.
Segments
Products
- Reagents and Kits
- Bacterial Expressions
- Algal Expressions
- Cell-free Expressions
- Mammalian Expressions
- Yeast Expressions
- Insect Expressions
- Others
- Services
- Others
Applications
- Industrial
- Therapeutics
- Research
End-Users
- Pharmaceuticals
- Academics
- Biotechnology
Regions
- Asia Pacific
- North America
- Latin America
- Europe
- Middle East & Africa
Key Players
- Becton, Dickinson & Company
- Thermo Fisher Scientific Inc.
- Takara Bio, Inc.
- Qiagen N.V
- Promega Corporation
- Oxford Expression Technologies Ltd.
- Synthetic Genomics Inc.
- New England Biolabs, Inc.
- Merck KGaA
- Bio-Rad Laboratories Inc.
- Agilent Technologies
- Genscript Biotech Corporation
Competitive Landscape
Key players competing in the global protein expression market include Becton, Dickinson & Company; Thermo Fisher Scientific Inc.; Takara Bio, Inc.; Qiagen N.V; Promega Corporation; Oxford Expression Technologies Ltd.; Synthetic Genomics Inc.; New England Biolabs, Inc.; Merck KGaA; Bio-Rad Laboratories Inc.; Agilent Technologies; and Genscript Biotech Corporation.
Some of these players are adopting several market strategies including acquisitions, mergers, collaborations, partnerships, capacity expansion, and product launches to increase their market shares.

Table Of Content
1. Executive Summary
2. Assumptions and Acronyms Used
3. Research Methodology
4. Protein Expression Market Overview
4.1. Introduction
4.1.1. Market Taxonomy
4.1.2. Market Definition
4.2. Macro-Economic Factors
4.2.1. Industry Outlook
4.3. Protein Expression Market Dynamics
4.3.1. Market Drivers
4.3.2. Market Restraints
4.3.3. Opportunity
4.3.4. Market Trends
4.4. Protein Expression Market - Supply Chain
4.5. Global Protein Expression Market Forecast
4.5.1. Protein Expression Market Size (US$ Mn) and Y-o-Y Growth
4.5.2. Protein Expression Market Size (000’ Units) and Y-o-Y Growth
4.5.3. Protein Expression Market Absolute $ Opportunity
5. Global Protein Expression Market Analysis and Forecast by Applications
5.1. Market Trends
5.2. Introduction
5.2.1. Basis Point Share (BPS) Analysis by Applications
5.2.2. Y-o-Y Growth Projections by Applications
5.3. Protein Expression Market Size and Volume Forecast by Applications
5.3.1. Industrial
5.3.2.
Therapeutics
5.3.3.
Research
5.4. Absolute $ Opportunity Assessment by Applications
5.5. Market Attractiveness/Growth Potential Analysis by Applications
6. Global Protein Expression Market Analysis and Forecast by End Users
6.1. Market Trends
6.2. Introduction
6.2.1. Basis Point Share (BPS) Analysis by End Users
6.2.2. Y-o-Y Growth Projections by End Users
6.3. Protein Expression Market Size and Volume Forecast by End Users
6.3.1. Pharmaceuticals
6.3.2.
Academics
6.3.3.
Biotechnology
6.4. Absolute $ Opportunity Assessment by End Users
6.5. Market Attractiveness/Growth Potential Analysis by End Users
7. Global Protein Expression Market Analysis and Forecast by Region
7.1. Market Trends
7.2. Introduction
7.2.1. Basis Point Share (BPS) Analysis by Region
7.2.2. Y-o-Y Growth Projections by Region
7.3. Protein Expression Market Size and Volume Forecast by Region
7.3.1. North America
7.3.2. Latin America
7.3.3. Europe
7.3.4. Asia Pacific
7.3.5. Middle East and Africa (MEA)
7.4. Absolute $ Opportunity Assessment by Region
7.5. Market Attractiveness/Growth Potential Analysis by Region
7.6. Global Protein Expression Demand Share Forecast, 2019-2026
8. North America Protein Expression Market Analysis and Forecast
8.1. Introduction
8.1.1. Basis Point Share (BPS) Analysis by Country
8.1.2. Y-o-Y Growth Projections by Country
8.2. North America Protein Expression Market Size and Volume Forecast by Country
8.2.1. U.S.
8.2.2. Canada
8.3. Absolute $ Opportunity Assessment by Country
8.4. North America Protein Expression Market Size and Volume Forecast by Applications
8.4.1. Industrial
8.4.2.
Therapeutics
8.4.3.
Research
8.5. Basis Point Share (BPS) Analysis by Applications
8.6. Y-o-Y Growth Projections by Applications
8.7. North America Protein Expression Market Size and Volume Forecast by End Users
8.7.1. Pharmaceuticals
8.7.2.
Academics
8.7.3.
Biotechnology
8.8. Basis Point Share (BPS) Analysis by End Users
8.9. Y-o-Y Growth Projections by End Users
8.10. Market Attractiveness/Growth Potential Analysis
8.10.1. By Country
8.10.2. By Product Type
8.10.3. By Application
8.11. North America Protein Expression Demand Share Forecast, 2019-2026
9. Latin America Protein Expression Market Analysis and Forecast
9.1. Introduction
9.1.1. Basis Point Share (BPS) Analysis by Country
9.1.2. Y-o-Y Growth Projections by Country
9.1.3. Latin America Average Pricing Analysis
9.2. Latin America Protein Expression Market Size and Volume Forecast by Country
9.2.1. Brazil
9.2.2. Mexico
9.2.3. Rest of Latin America
9.3. Absolute $ Opportunity Assessment by Country
9.4. Latin America Protein Expression Market Size and Volume Forecast by Applications
9.4.1. Industrial
9.4.2.
Therapeutics
9.4.3.
Research
9.5. Basis Point Share (BPS) Analysis by Applications
9.6. Y-o-Y Growth Projections by Applications
9.7. Latin America Protein Expression Market Size and Volume Forecast by End Users
9.7.1. Pharmaceuticals
9.7.2.
Academics
9.7.3.
Biotechnology
9.8. Basis Point Share (BPS) Analysis by End Users
9.9. Y-o-Y Growth Projections by End Users
9.10. Market Attractiveness/Growth Potential Analysis
9.10.1. By Country
9.10.2. By Product Type
9.10.3. By Application
9.11. Latin America Protein Expression Demand Share Forecast, 2019-2026
10. Europe Protein Expression Market Analysis and Forecast
10.1. Introduction
10.1.1. Basis Point Share (BPS) Analysis by Country
10.1.2. Y-o-Y Growth Projections by Country
10.1.3. Europe Average Pricing Analysis
10.2. Europe Protein Expression Market Size and Volume Forecast by Country
10.2.1. Germany
10.2.2. France
10.2.3. Italy
10.2.4. U.K.
10.2.5. Spain
10.2.6. Russia
10.2.7. Rest of Europe
10.3. Absolute $ Opportunity Assessment by Country
10.4. Europe Protein Expression Market Size and Volume Forecast by Applications
10.4.1. Industrial
10.4.2.
Therapeutics
10.4.3.
Research
10.5. Basis Point Share (BPS) Analysis by Applications
10.6. Y-o-Y Growth Projections by Applications
10.7. Europe Protein Expression Market Size and Volume Forecast by End Users
10.7.1. Pharmaceuticals
10.7.2.
Academics
10.7.3.
Biotechnology
10.8. Basis Point Share (BPS) Analysis by End Users
10.9. Y-o-Y Growth Projections by End Users
10.10. Market Attractiveness/Growth Potential Analysis
10.10.1. By Country
10.10.2. By Product Type
10.10.3. By Application
10.11. Europe Protein Expression Demand Share Forecast, 2019-2026
11. Asia Pacific Protein Expression Market Analysis and Forecast
11.1. Introduction
11.1.1. Basis Point Share (BPS) Analysis by Country
11.1.2. Y-o-Y Growth Projections by Country
11.1.3. Asia Pacific Average Pricing Analysis
11.2. Asia Pacific Protein Expression Market Size and Volume Forecast by Country
11.2.1. China
11.2.2. Japan
11.2.3. South Korea
11.2.4. India
11.2.5. Australia
11.2.6. Rest of Asia Pacific (APAC)
11.3. Absolute $ Opportunity Assessment by Country
11.4. Asia Pacific Protein Expression Market Size and Volume Forecast by Applications
11.4.1. Industrial
11.4.2.
Therapeutics
11.4.3.
Research
11.5. Basis Point Share (BPS) Analysis by Applications
11.6. Y-o-Y Growth Projections by Applications
11.7. Asia Pacific Protein Expression Market Size and Volume Forecast by End Users
11.7.1. Pharmaceuticals
11.7.2.
Academics
11.7.3.
Biotechnology
11.8. Basis Point Share (BPS) Analysis by End Users
11.9. Y-o-Y Growth Projections by End Users
11.10. Market Attractiveness/Growth Potential Analysis
11.10.1. By Country
11.10.2. By Product Type
11.10.3. By Application
11.11. Asia Pacific Protein Expression Demand Share Forecast, 2019-2026
12. Middle East & Africa Protein Expression Market Analysis and Forecast
12.1. Introduction
12.1.1. Basis Point Share (BPS) Analysis by Country
12.1.2. Y-o-Y Growth Projections by Country
12.1.3. Middle East & Africa Average Pricing Analysis
12.2. Middle East & Africa Protein Expression Market Size and Volume Forecast by Country
12.2.1. Saudi Arabia
12.2.2. South Africa
12.2.3. UAE
12.2.4. Rest of Middle East & Africa (MEA)
12.3. Absolute $ Opportunity Assessment by Country
12.4. Middle East & Africa Protein Expression Market Size and Volume Forecast by Applications
12.4.1. Industrial
12.4.2.
Therapeutics
12.4.3.
Research
12.5. Basis Point Share (BPS) Analysis by Applications
12.6. Y-o-Y Growth Projections by Applications
12.7. Middle East & Africa Protein Expression Market Size and Volume Forecast by End Users
12.7.1. Pharmaceuticals
12.7.2.
Academics
12.7.3.
Biotechnology
12.8. Basis Point Share (BPS) Analysis by End Users
12.9. Y-o-Y Growth Projections by End Users
12.10. Market Attractiveness/Growth Potential Analysis
12.10.1. By Country
12.10.2. By Product Type
12.10.3. By Application
12.11. Middle East & Africa Protein Expression Demand Share Forecast, 2019-2026
13. Competition Landscape
13.1. Global Protein Expression Market: Market Share Analysis
13.2. Protein Expression Distributors and Customers
13.3. Protein Expression Market: Competitive Dashboard
13.4. Company Profiles (Details: Overview, Financials, Developments, Strategy)
13.4.1. Becton, Dickinson & Company
13.4.2.
Thermo Fisher Scientific Inc.
13.4.3.
Takara Bio, Inc.
13.4.4.
Qiagen N.V
13.4.5.
Promega Corporation