The global protein expression market size is anticipated to expand at a substantial CAGR during the forecast period, 2021–2028. The growth of the market is attributed to the elderly growing population, age-related disorders, and the incidence of chronic diseases including cancer are all on the rise.

Protein expression is the process of synthesizing, modifying, and regulating proteins. Protein expression is the use of experimental tools and procedures to help in the production of proteins. Protein expression is a biotechnological procedure for producing a specific protein, which is commonly accomplished by manipulating gene expression in an animal to produce huge amounts of recombinant genes. The method can be used to make and filter the target protein inside or outside of a cell.
Proteins made utilizing the protein expression approach can be employed in industrial operations as well as for diagnosing and treating diseases. Protein expression generates the enzymes or substrates needed for further investigation. The advancement of genetic engineering and recombinant technology has opened countless opportunities for homogeneous protein expression and separation in academic, therapeutic, and industrial settings. Biotechnology advancements have made large-scale production and separation of recombinant proteins possible.
Market Trends, Drivers, Restraints, and Opportunities
- Rising biotechnology need and the rise of the biomedical industry is expected to propel the market growth in the coming years.
- Protein expression solutions for research and production are becoming more prominent owing to the accessibility of new and improved technologies to fulfill the demand for pharmaceuticals and biologics product makers are projected to spur the market expansion during the forecast period.
- Increasing demand for therapeutic proteins including hormones, insulin, monoclonal, vaccines, and antibodies are key factors boosting the market growth in the coming years.
- Scarcity of skilled healthcare workers as well as a lack of knowledge is estimated to hinder the market growth.
- Low R&D investment and the increased price of proteomics research possess as key factors that can impede the market expansion in the coming years.
- Rapid advancements in medical technology, improved disease diagnosis, and the expansion of healthcare in developing economies are anticipated to create significant opportunities for the market players.
Scope of the Report
The report on the global protein expression market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes | Details |
Report Title | Protein Expression Market - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast |
Base Year | 2020 |
Historic Data | 2018–2019 |
Forecast Period | 2021–2028 |
Segmentation | Products (Reagents and Kits [Bacterial Expressions, Algal Expressions, Cell-free Expressions, Mammalian Expressions, Yeast Expressions, Insect Expressions, and Others], Services, and Others), Applications (Industrial, Therapeutics, and Research), End-users (Pharmaceuticals, Academics, and Biotechnology) |
Regional Scope | Asia Pacific, North America, Latin America, Europe, and Middle East & Africa |
Report Coverage | Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, and Trends, and Revenue Forecast |
Key Players Covered in the Report | Becton, Dickinson & Company; Thermo Fisher Scientific Inc.; Takara Bio, Inc.; Qiagen N.V; Promega Corporation; Oxford Expression Technologies Ltd.; Synthetic Genomics Inc.; New England Biolabs, Inc.; Merck KGaA; Bio-Rad Laboratories Inc.; Agilent Technologies; and Genscript Biotech Corporation |
Market Segment Insights
Cell-free expressions segment is projected to account for a key market share
Based on products, the global protein expression market is divided into reagents and kits [bacterial expressions, algal expressions, cell-free expressions, mammalian expressions, yeast expressions, insect expressions, and others. The cell-free expressions segment is expected to hold a key share of the market during the forecast period due to protein expression is done without the usage of live cells. This technology offers numerous advantages over all other protein expression methods, and it is extensively caused as a result of these advantages. Because of the benefits of cell-free protein approaches, including enhanced pace, the capacity to produce hazardous proteins, and the simplicity of amino acid class-specific labeling, among others, the cell expression market is expected to develop.
Large screening for shortened proteins, production of proteins that are harmful to expression carriers in vivo, production of proteins containing amino acids, and insertion of post-translational changes are only a few of the uses of cell-free expression. Protein nano-crystallography is the newest trend in cell-free expression research. This method can create and characterize stable protein microcrystals down to the atomic level.
Therapeutics segment is expected to grow at a significant pace
On the basis of applications, the market is segmented into industrial, therapeutics, and research. The therapeutics segment is expected to constitute a key share of the market in the coming years owing to the increasing prevalence of the disease, as well as increased R&D activities, which are driving this segment's rise. Proteomics-based research is on the rise, as is the incidence of chronic diseases around the world, which explains the substantial proportion of this market.
Peptide hormones, vaccinations, therapeutic enzymes, monoclonal antibodies, antibodies, cytokines, and blood factors, are examples of therapeutic proteins that are prescribed to treat chronic diseases including diabetes, cancer, and multiple sclerosis. In the manufacture of biological drugs, these proteins have improved quality, precision, and effectiveness.
Pharmaceuticals segment is anticipated to register at a substantial CAGR
In terms of end-users, the global protein expression market is segregated into pharmaceuticals, academics, and biotechnology. The pharmaceuticals segment is expected to represent a key share of the market during the forecast period due to the increased focus on proteomics research and biologics manufacture.

United States in North America is anticipated to dominate the market
On the basis of regions, the market is classified as Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. United States in North America is anticipated to dominate the market at an impressive CAGR during the forecast period. The regional market growth can be attributed to the factors driving the protein expression market in the United States include investment in research and development, a rise in the use of protein technology, and the region's rapidly evolving healthcare companies. The existence of multiple enterprises in the region itself is another element pushing the protein expression market in the United States.
The market's prospects for expansion are being boosted by increased research activity in the United States pharmaceutical industry. Developments in the area of proteomics have grown the industry even further in the United States.

Segments
Segments Covered in the Report
The global protein expression market has been segmented based on
Products
- Reagents and Kits
- Bacterial Expressions
- Algal Expressions
- Cell-free Expressions
- Mammalian Expressions
- Yeast Expressions
- Insect Expressions
- Others
- Services
- Others
Applications
- Industrial
- Therapeutics
- Research
End-users
- Pharmaceuticals
- Academics
- Biotechnology
Regions
- Asia Pacific
- North America
- Latin America
- Europe
- Middle East & Africa
Key Players
- Becton, Dickinson & Company
- Thermo Fisher Scientific Inc.
- Takara Bio, Inc.
- Qiagen N.V
- Promega Corporation
- Oxford Expression Technologies Ltd.
- Synthetic Genomics Inc.
- New England Biolabs, Inc.
- Merck KGaA
- Bio-Rad Laboratories Inc.
- Agilent Technologies
- Genscript Biotech Corporation
Competitive Landscape
Key players competing in the global protein expression market include Becton, Dickinson & Company; Thermo Fisher Scientific Inc.; Takara Bio, Inc.; Qiagen N.V; Promega Corporation; Oxford Expression Technologies Ltd.; Synthetic Genomics Inc.; New England Biolabs, Inc.; Merck KGaA; Bio-Rad Laboratories Inc.; Agilent Technologies; and Genscript Biotech Corporation. Some of these players are adopting several market strategies including acquisitions, mergers, collaborations, partnerships, capacity expansion, and product launches to increase their market shares.
