Report Description
Alpha-1 Antitrypsin Deficiency Treatment Market Outlook 2031:
The Alpha-1 antitrypsin Deficiency Treatment Market size was valued at USD 1.49 Billion in 2022 and is projected to reach USD 3.78 Billion by 2031, expanding at a CAGR of 10.9% during the forecast period 2023 - 2031. Alpha-1 antitrypsin deficiency or AAT deficiency, is a genetic disorder characterized by a lack of AAT protein in the body. It is essential for the lungs and liver to defend themselves against the harmful effects of other proteins.
The deficiency of AAT can develop liver cirrhosis, chronic obstructive pulmonary disease (COPD), or emphysema. Tests such as genetics and blood tests can diagnose this disease. Medicines such as bronchodilators and corticosteroids, which can be injected intravenously or inhaled, are frequently used for treatment methods such as augmentation therapy, pulmonary rehabilitation, and oxygen therapy.
Alpha-1 Antitrypsin Deficiency Treatment Market Trends, Drivers, Restraints, and Opportunities:
- Increasing improvement in the diagnosis of alpha1-antitrypsin deficiency is estimated to boost the growth of the market.
- Various technological advancements in the diagnostic methods and the development of innovative processes for the production & purification of AAT are acting as growth-inducing factors for the market.
- High prevalence of chronic respiratory diseases across the world is the major driver for the growth of the market.
- Widespread adoption of augmentation therapy is providing a thrust to the market growth.
- Increasing cost of drugs can create challenges for the market growth.
- Stringent regulations along with less availability of plasma fractionation capacity can restrain the growth of the market.
- Increasing demand for deficiency treatment, improving economic scenario, increasing awareness regarding alpha1-antitrypsin deficiency, surging investment for the development of advanced and technical products are some of the factors that can accelerate the growth.
- The PlasmaTech SDF (salt diafiltration) process is a plasma-based platform was introduced for mass production of orphan protein therapeutics such as alpha-1 antitrypsin Thus, such innovation can create lucrative opportunities for the industry players.
Scope of Alpha-1 Antitrypsin Deficiency Treatment Market Report
The report on alpha-1 antitrypsin deficiency treatment market includes an assessment of the market, size, share, trends, segments, and regional markets. Overview and dynamics have been included in the report.
Attributes
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Details
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Report Title
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Alpha-1 Antitrypsin Deficiency Treatment Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast
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Base Year
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2022
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Historic Data
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2016 & 2021
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Forecast Period
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2023–2031
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Segmentation
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Treatment Types (Augmentation Therapy, Bronchodilators, Corticosteroids, Oxygen Therapy, and Others), Route of Administration (Parental, Inhalation, and Oral), End-users (Hospitals, Specialty Clinics, and Others)
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Regional Scope
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Asia Pacific, North America, Europe, Latin America, and Middle East & Africa
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Report Coverage
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Market scope, analysis, share, competitive analysis, growth facts, restraints, opportunities, and revenue forecast
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Key Players Covered in the Report
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Grifols, S.A., Kamada Pharmaceuticals., CSL, Arrowhead Pharmaceuticals, Inc., CHIESI Farmaceutici S.p.A., AstraZeneca, Henry Schein, Inc., Healthy Life Pharma Private Limited., Hovione, Switzer Life science Pvt. Ltd., Cyndea Pharma, Anuh Pharma Ltd., Cipla Inc., Pfizer Inc., Anantco Enterprises Pvt. Ltd.
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Alpha-1 Antitrypsin Deficiency Treatment Market Segment Insights
Augmentation therapy segment is projected to hold significant market share
In the terms of treatment types, the market can be divided into augmentation therapy, bronchodilators, corticosteroids, oxygen therapy and others. The augmentation therapy segment accounted for a major market share in 2020, and is expected to continue to grow at a robust rate during the forecast period. This is due to high acceptance of the therapy in developed regions such as the US and Europe.
Inhalation segment is anticipated to account for a substantial share
Based on route of administration, the alpha-1 antitrypsin deficiency treatment market can be segregated into parental, inhalation and oral. The inhalation segment is estimated to hold a substantial market during the forecast period owing to increasing focus on R&D for developing inhalation formulation of existing alpha-1 antitrypsin.
Hospital segment accounted for a major market share in 2020
On the basis of end-users, the market can be divided into hospitals, specialty clinics, and others. The hospitals segment dominated the global market in 2020 due to rising patients of COPD and presence of favourable reimbursement programs in developed and emerging countries.
North America to dominates the market
In terms of regions, the alpha-1 antitrypsin deficiency treatment market can be categorized as Asia Pacific, North America, Europe, Latin America, and the Middle East & Africa.
North America is estimated to dominate the market in 2020 due to growing prevalence of alpha1-antitrypsin deficiency along with increasing healthcare expenditure, while the market in Asia Pacific is expected to grow at a robust CAGR during the forecast period due to increasing initiatives by the government to control genetic disorders and improvement in diagnostics techniques.
Segments
By Treatment Types
- Augmentation Therapy
- Bronchodilators
- Corticosteroids
- Oxygen Therapy
- Others
By Route of Administration
By End-users
- Hospitals
- Specialty Clinics
- Others
By Regions
- Asia Pacific
- North America
- Latin America
- Europe
- Middle East & Africa
By Key Players
- Grifols, S.A.
- Kamada Pharmaceuticals.
- CSL
- Arrowhead Pharmaceuticals, Inc.
- CHIESI Farmaceutici S.p.A.
- AstraZeneca
- Henry Schein, Inc.
- Healthy Life Pharma Private Limited.
- Hovione
- Switzer Life science Pvt. Ltd.
- Cyndea Pharma
- Anuh Pharma Ltd.
- Cipla Inc.
- Pfizer Inc.
- Anantco Enterprises Pvt. Ltd.
Competitive Landscape
Key players in the alpha-1 antitrypsin deficiency treatment market are Grifols, S.A., Kamada Pharmaceuticals., CSL, Arrowhead Pharmaceuticals, Inc., CHIESI Farmaceutici S.p.A., AstraZeneca, Henry Schein, Inc., Healthy Life Pharma Private Limited.,
Hovione, Switzer Life science Pvt. Ltd., Cyndea Pharma, Anuh Pharma Ltd., Cipla Inc., Pfizer Inc., Anantco Enterprises Pvt. Ltd., among other domestic and global players.These players engage in mergers & acquisitions, collaborations, agreements, and partnerships to strengthen their geographical presence.

Table Of Content
1. Executive Summary
2. Assumptions and Acronyms Used
3. Research Methodology
4. Alpha-1 Antitrypsin Deficiency Treatment Market Overview
4.1. Introduction
4.1.1. Market Taxonomy
4.1.2. Market Definition
4.2. Macro-Economic Factors
4.2.1. Industry Outlook
4.3. Alpha-1 Antitrypsin Deficiency Treatment Market Dynamics
4.3.1. Market Drivers
4.3.2. Market Restraints
4.3.3. Opportunity
4.3.4. Market Trends
4.4. Alpha-1 Antitrypsin Deficiency Treatment Market - Supply Chain
4.5. Global Alpha-1 Antitrypsin Deficiency Treatment Market Forecast
4.5.1. Alpha-1 Antitrypsin Deficiency Treatment Market Size (US$ Mn) and Y-o-Y Growth
4.5.2. Alpha-1 Antitrypsin Deficiency Treatment Market Size (000’ Units) and Y-o-Y Growth
4.5.3. Alpha-1 Antitrypsin Deficiency Treatment Market Absolute $ Opportunity
5. Global Alpha-1 Antitrypsin Deficiency Treatment Market Analysis and Forecast by Types
5.1. Market Trends
5.2. Introduction
5.2.1. Basis Point Share (BPS) Analysis by Types
5.2.2. Y-o-Y Growth Projections by Types
5.3. Alpha-1 Antitrypsin Deficiency Treatment Market Size and Volume Forecast by Types
5.3.1. Augmentation Therapy
5.3.2.
Bronchodilators
5.3.3.
Corticosteroids
5.3.4.
Oxygen Therapy
5.3.5.
Others
5.4. Absolute $ Opportunity Assessment by Types
5.5. Market Attractiveness/Growth Potential Analysis by Types
6. Global Alpha-1 Antitrypsin Deficiency Treatment Market Analysis and Forecast by Region
6.1. Market Trends
6.2. Introduction
6.2.1. Basis Point Share (BPS) Analysis by Region
6.2.2. Y-o-Y Growth Projections by Region
6.3. Alpha-1 Antitrypsin Deficiency Treatment Market Size and Volume Forecast by Region
6.3.1. North America
6.3.2. Latin America
6.3.3. Europe
6.3.4. Asia Pacific
6.3.5. Middle East and Africa (MEA)
6.4. Absolute $ Opportunity Assessment by Region
6.5. Market Attractiveness/Growth Potential Analysis by Region
6.6. Global Alpha-1 Antitrypsin Deficiency Treatment Demand Share Forecast, 2019-2026
7. North America Alpha-1 Antitrypsin Deficiency Treatment Market Analysis and Forecast
7.1. Introduction
7.1.1. Basis Point Share (BPS) Analysis by Country
7.1.2. Y-o-Y Growth Projections by Country
7.2. North America Alpha-1 Antitrypsin Deficiency Treatment Market Size and Volume Forecast by Country
7.2.1. U.S.
7.2.2. Canada
7.3. Absolute $ Opportunity Assessment by Country
7.4. North America Alpha-1 Antitrypsin Deficiency Treatment Market Size and Volume Forecast by Types
7.4.1. Augmentation Therapy
7.4.2.
Bronchodilators
7.4.3.
Corticosteroids
7.4.4.
Oxygen Therapy
7.4.5.
Others
7.5. Basis Point Share (BPS) Analysis by Types
7.6. Y-o-Y Growth Projections by Types
7.7. Market Attractiveness/Growth Potential Analysis
7.7.1. By Country
7.7.2. By Product Type
7.7.3. By Application
7.8. North America Alpha-1 Antitrypsin Deficiency Treatment Demand Share Forecast, 2019-2026
8. Latin America Alpha-1 Antitrypsin Deficiency Treatment Market Analysis and Forecast
8.1. Introduction
8.1.1. Basis Point Share (BPS) Analysis by Country
8.1.2. Y-o-Y Growth Projections by Country
8.1.3. Latin America Average Pricing Analysis
8.2. Latin America Alpha-1 Antitrypsin Deficiency Treatment Market Size and Volume Forecast by Country
8.2.1. Brazil
8.2.2. Mexico
8.2.3. Rest of Latin America
8.3. Absolute $ Opportunity Assessment by Country
8.4. Latin America Alpha-1 Antitrypsin Deficiency Treatment Market Size and Volume Forecast by Types
8.4.1. Augmentation Therapy
8.4.2.
Bronchodilators
8.4.3.
Corticosteroids
8.4.4.
Oxygen Therapy
8.4.5.
Others
8.5. Basis Point Share (BPS) Analysis by Types
8.6. Y-o-Y Growth Projections by Types
8.7. Market Attractiveness/Growth Potential Analysis
8.7.1. By Country
8.7.2. By Product Type
8.7.3. By Application
8.8. Latin America Alpha-1 Antitrypsin Deficiency Treatment Demand Share Forecast, 2019-2026
9. Europe Alpha-1 Antitrypsin Deficiency Treatment Market Analysis and Forecast
9.1. Introduction
9.1.1. Basis Point Share (BPS) Analysis by Country
9.1.2. Y-o-Y Growth Projections by Country
9.1.3. Europe Average Pricing Analysis
9.2. Europe Alpha-1 Antitrypsin Deficiency Treatment Market Size and Volume Forecast by Country
9.2.1. Germany
9.2.2. France
9.2.3. Italy
9.2.4. U.K.
9.2.5. Spain
9.2.6. Russia
9.2.7. Rest of Europe
9.3. Absolute $ Opportunity Assessment by Country
9.4. Europe Alpha-1 Antitrypsin Deficiency Treatment Market Size and Volume Forecast by Types
9.4.1. Augmentation Therapy
9.4.2.
Bronchodilators
9.4.3.
Corticosteroids
9.4.4.
Oxygen Therapy
9.4.5.
Others
9.5. Basis Point Share (BPS) Analysis by Types
9.6. Y-o-Y Growth Projections by Types
9.7. Market Attractiveness/Growth Potential Analysis
9.7.1. By Country
9.7.2. By Product Type
9.7.3. By Application
9.8. Europe Alpha-1 Antitrypsin Deficiency Treatment Demand Share Forecast, 2019-2026
10. Asia Pacific Alpha-1 Antitrypsin Deficiency Treatment Market Analysis and Forecast
10.1. Introduction
10.1.1. Basis Point Share (BPS) Analysis by Country
10.1.2. Y-o-Y Growth Projections by Country
10.1.3. Asia Pacific Average Pricing Analysis
10.2. Asia Pacific Alpha-1 Antitrypsin Deficiency Treatment Market Size and Volume Forecast by Country
10.2.1. China
10.2.2. Japan
10.2.3. South Korea
10.2.4. India
10.2.5. Australia
10.2.6. Rest of Asia Pacific (APAC)
10.3. Absolute $ Opportunity Assessment by Country
10.4. Asia Pacific Alpha-1 Antitrypsin Deficiency Treatment Market Size and Volume Forecast by Types
10.4.1. Augmentation Therapy
10.4.2.
Bronchodilators
10.4.3.
Corticosteroids
10.4.4.
Oxygen Therapy
10.4.5.
Others
10.5. Basis Point Share (BPS) Analysis by Types
10.6. Y-o-Y Growth Projections by Types
10.7. Market Attractiveness/Growth Potential Analysis
10.7.1. By Country
10.7.2. By Product Type
10.7.3. By Application
10.8. Asia Pacific Alpha-1 Antitrypsin Deficiency Treatment Demand Share Forecast, 2019-2026
11. Middle East & Africa Alpha-1 Antitrypsin Deficiency Treatment Market Analysis and Forecast
11.1. Introduction
11.1.1. Basis Point Share (BPS) Analysis by Country
11.1.2. Y-o-Y Growth Projections by Country
11.1.3. Middle East & Africa Average Pricing Analysis
11.2. Middle East & Africa Alpha-1 Antitrypsin Deficiency Treatment Market Size and Volume Forecast by Country
11.2.1. Saudi Arabia
11.2.2. South Africa
11.2.3. UAE
11.2.4. Rest of Middle East & Africa (MEA)
11.3. Absolute $ Opportunity Assessment by Country
11.4. Middle East & Africa Alpha-1 Antitrypsin Deficiency Treatment Market Size and Volume Forecast by Types
11.4.1. Augmentation Therapy
11.4.2.
Bronchodilators
11.4.3.
Corticosteroids
11.4.4.
Oxygen Therapy
11.4.5.
Others
11.5. Basis Point Share (BPS) Analysis by Types
11.6. Y-o-Y Growth Projections by Types
11.7. Market Attractiveness/Growth Potential Analysis
11.7.1. By Country
11.7.2. By Product Type
11.7.3. By Application
11.8. Middle East & Africa Alpha-1 Antitrypsin Deficiency Treatment Demand Share Forecast, 2019-2026
12. Competition Landscape
12.1. Global Alpha-1 Antitrypsin Deficiency Treatment Market: Market Share Analysis
12.2. Alpha-1 Antitrypsin Deficiency Treatment Distributors and Customers
12.3. Alpha-1 Antitrypsin Deficiency Treatment Market: Competitive Dashboard
12.4. Company Profiles (Details: Overview, Financials, Developments, Strategy)
12.4.1. Grifols, S.A.
12.4.2.
Kamada Pharmaceuticals.
12.4.3.
CSL
12.4.4.
Arrowhead Pharmaceuticals, Inc.
12.4.5.
CHIESI Farmaceutici S.p.A.
12.4.6.
AstraZeneca
12.4.7.
Henry Schein, Inc.
12.4.8.
He