Report Description
The plasma fractionation market size was valued at USD 26 billion in 2021 and is projected to reach USD 36.9 billion by 2030, expanding at a CAGR of around 6% during the forecast period, 2022 – 2030. The growth of the market is attributed to the increased risk of contagious infections.
Fractionation is a method of separating a specific amount of a mixture. Moreover, plasma is the fluid component of blood that is segregated to produce immunoglobulins and albumin. These plasma derivatives have therapeutic properties and are used to treat a variety of blood plasma diseases. It is often used during surgical operations to prevent excessive blood loss. Immunoglobulins are also used to treat primary and secondary immunological deficits.
The COVID-19 pandemic has affected every industry in the world. The COVID-19 pandemic has resulted in a decline in the frequency of blood donations and plasma collections, which has hampered the market expansion due to a shortage of raw materials. In the early stages of nationwide lockdowns, a decrease in raw material supply was offset by a decrease in demand for plasma derivatives, elective surgical operations had to be postponed, and care for other medical disorders was also limited.
Market Trends, Drivers, Restraints, and Opportunities
- Increased usage of immunoglobulins in therapeutic applications is projected to drive the market.
- Rising prevalence of AATD and respiratory diseases is expected to fuel the market during the projected period.
- Increasing number of plasma collecting centers is estimated to boost the market in the coming years.
- High costs and limited reimbursement for plasma products, as well as the growing usage of recombinant alternatives, are anticipated to hinder the market growth.
- Increasing prevalence of bleeding illnesses is projected to create immense opportunities for the market players.
Scope of the Report
The report on the global plasma fractionation market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes
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Details
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Report Title
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Plasma Fractionation Market - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast
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Base Year
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2021
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Historic Data
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2019–2020
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Forecast Period
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2022 – 2030
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Segmentation
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Applications (Rheumatology, Hematology, Immunology, and Neurology), Products (PCC, von Willebrand Factor, Protease Inhibitors, Albumin, and Immunoglobulins), and End-users (Hospitals & Clinics and Clinical Research)
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Regional Scope
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Asia Pacific, North America, Latin America, Europe, and Middle East & Africa
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Report Coverage
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Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, and Trends, and Revenue Forecast
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Key Players Covered in the Report
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Hemarus Therapeutics Limited; Fusion Healthcare; Virchow Biotech Private Limited; PlasmaGen BioSciences Pvt. Ltd.; ADMA Biologics, Inc.; Centurion Pharma; KabaFusion; Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd.; SK Plasma; Bharat Serum Vaccines Limited; Intas Pharmaceuticals Ltd.; Shanghai Raas Blood Products Co., Ltd.; Emergent BioSolutions; Japan Blood Products Organization; Bio Products Ltd.; GC Pharma; China Biologic Products Holdings Inc.; Sanquin; Biotest AG; LFB; Kedrion S.P.A; Octapharma AG; Shire; Grifols, S.A.; and CSL
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Market Segment Insights
The immunoglobulins segment is projected to expand at a high CAGR during the forecast period
Based on products, the market is segregated into PCC, von Willebrand factor, protease inhibitors, albumin, and immunoglobulins. The immunology segment accounted for a major market share in 2021 and is projected to expand at a high CAGR during the forecast period. Off-label immunoglobulin indications and applications account for a major portion of this segment. Immunoglobulins are also used to fight the consequences of immunosenescence, or decreases in immunity that occur with age. Immunoglobulin use is projected to rise in the coming years as infections and illnesses become more common.
The neurology segment accounted for a major market share in 2021
On the basis of applications, the market is fragmented into rheumatology, hematology, immunology, and neurology. This is mostly due to the fact that IVIg produces a faster response than steroids or oral immunosuppressants. IVIg is beneficial for a variety of central nervous and peripheral system problems. IVIg is also being tested for other neurological diseases, such as Alzheimer's disease.
The hospitals & clinics segment is estimated to grow at a rapid pace during the forecast period
In terms of end-users, the market is divided into hospitals & clinics and clinical research. The hospitals & clinics segment is estimated to grow at a rapid pace during the forecast period as a result of improved infrastructure and hospital-based health-care services. In addition, hospitals are increasingly using plasma fractionation products off-label to treat a variety of disorders.
North America dominated the market in 2021
On the basis of regions, the market is classified as Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. North America dominated the market in 2021. Growth of the market in the region is attributed to increasing use of immunoglobulins in neurological and autoimmune illnesses. Autoimmune illnesses are on the rise, as is the use of preventative medications among those who have been diagnosed. Large number of registered hemophilic patients is also estimated to drive the market.

Segments
The global plasma fractionation market has been segmented on the basis of
Applications
- Rheumatology
- Hematology
- Immunology
- Neurology
Products
- PCC
- von Willebrand Factor
- Protease Inhibitors
- Albumin
- Immunoglobulins
End-users
- Hospitals & Clinics
- Clinical Research
Regions
- Asia Pacific
- North America
- Latin America
- Europe
- Middle East & Africa
Key Players
- Hemarus Therapeutics Limited
- Fusion Healthcare
- Virchow Biotech Private Limited
- PlasmaGen BioSciences Pvt. Ltd.
- ADMA Biologics, Inc.
- Centurion Pharma
- KabaFusion
- Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd.
- SK Plasma
- Bharat Serum Vaccines Limited
- Intas Pharmaceuticals Ltd.
- Shanghai Raas Blood Products Co., Ltd.
- Emergent BioSolutions
- Japan Blood Products Organization
- Bio Products Ltd.
- GC Pharma
- China Biologic Products Holdings Inc.
- Sanquin
- Biotest AG
- LFB
- Kedrion S.P.A
- Octapharma AG
- Shire
- Grifols, S.A.
- CSL
Competitive Landscape
Key players competing in the plasma fractionation market include Hemarus Therapeutics Limited; Fusion Healthcare; Virchow Biotech Private Limited; PlasmaGen BioSciences Pvt. Ltd.; ADMA Biologics, Inc.; Centurion Pharma; KabaFusion; Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd.; SK Plasma; Bharat Serum Vaccines Limited; Intas Pharmaceuticals Ltd.; Shanghai Raas Blood Products Co., Ltd.; Emergent BioSolutions; Japan Blood Products Organization; Bio Products Ltd.; GC Pharma; China Biologic Products Holdings Inc.; Sanquin; Biotest AG; LFB; Kedrion S.P.A; Octapharma AG; Shire; Grifols, S.A.; and CSL. Some of these players are using several business strategies including mergers, acquisitions, partnerships, collaborations, capacity expansion, and product launches to enhance their market shares. For instance,
- In January 2022, Permira, a multinational investment corporation, has declared its intention to buy Kedrion and merge it with BPL.
- In August 2021, CSL received FDA approval for the novel BERINERT Administration Kit, which will make it easier for patients to use.
Frequently Asked Questions
North America dominated the plasma fractionation market in 2021.
The plasma fractionation market size was valued at USD 26 billion in 2021.
The plasma fractionation market is projected to reach USD 36.9 billion by 2030.
The plasma fractionation market is projected to expand at a CAGR of around 6% during the forecast period, 2022 – 2030.
The immunoglobulins segment is projected to expand at a high CAGR during the forecast period.
Table Of Content
1. Executive Summary
2. Assumptions and Acronyms Used
3. Research Methodology
4. Plasma Fractionation Market Overview
4.1. Introduction
4.1.1. Market Taxonomy
4.1.2. Market Definition
4.2. Macro-Economic Factors
4.2.1. Industry Outlook
4.3. Plasma Fractionation Market Dynamics
4.3.1. Market Drivers
4.3.2. Market Restraints
4.3.3. Opportunity
4.3.4. Market Trends
4.4. Plasma Fractionation Market - Supply Chain
4.5. Global Plasma Fractionation Market Forecast
4.5.1. Plasma Fractionation Market Size (US$ Mn) and Y-o-Y Growth
4.5.2. Plasma Fractionation Market Size (000’ Units) and Y-o-Y Growth
4.5.3. Plasma Fractionation Market Absolute $ Opportunity
5. Global Plasma Fractionation Market Analysis and Forecast by Applications
5.1. Market Trends
5.2. Introduction
5.2.1. Basis Point Share (BPS) Analysis by Applications
5.2.2. Y-o-Y Growth Projections by Applications
5.3. Plasma Fractionation Market Size and Volume Forecast by Applications
5.3.1. Rheumatology
5.3.2.
Hematology
5.3.3.
Immunology
5.3.4.
Neurology
5.4. Absolute $ Opportunity Assessment by Applications
5.5. Market Attractiveness/Growth Potential Analysis by Applications
6. Global Plasma Fractionation Market Analysis and Forecast by End Users
6.1. Market Trends
6.2. Introduction
6.2.1. Basis Point Share (BPS) Analysis by End Users
6.2.2. Y-o-Y Growth Projections by End Users
6.3. Plasma Fractionation Market Size and Volume Forecast by End Users
6.3.1. Hospitals & Clinics
6.3.2.
Clinical Research
6.4. Absolute $ Opportunity Assessment by End Users
6.5. Market Attractiveness/Growth Potential Analysis by End Users
7. Global Plasma Fractionation Market Analysis and Forecast by Region
7.1. Market Trends
7.2. Introduction
7.2.1. Basis Point Share (BPS) Analysis by Region
7.2.2. Y-o-Y Growth Projections by Region
7.3. Plasma Fractionation Market Size and Volume Forecast by Region
7.3.1. North America
7.3.2. Latin America
7.3.3. Europe
7.3.4. Asia Pacific
7.3.5. Middle East and Africa (MEA)
7.4. Absolute $ Opportunity Assessment by Region
7.5. Market Attractiveness/Growth Potential Analysis by Region
7.6. Global Plasma Fractionation Demand Share Forecast, 2019-2026
8. North America Plasma Fractionation Market Analysis and Forecast
8.1. Introduction
8.1.1. Basis Point Share (BPS) Analysis by Country
8.1.2. Y-o-Y Growth Projections by Country
8.2. North America Plasma Fractionation Market Size and Volume Forecast by Country
8.2.1. U.S.
8.2.2. Canada
8.3. Absolute $ Opportunity Assessment by Country
8.4. North America Plasma Fractionation Market Size and Volume Forecast by Applications
8.4.1. Rheumatology
8.4.2.
Hematology
8.4.3.
Immunology
8.4.4.
Neurology
8.5. Basis Point Share (BPS) Analysis by Applications
8.6. Y-o-Y Growth Projections by Applications
8.7. North America Plasma Fractionation Market Size and Volume Forecast by End Users
8.7.1. Hospitals & Clinics
8.7.2.
Clinical Research
8.8. Basis Point Share (BPS) Analysis by End Users
8.9. Y-o-Y Growth Projections by End Users
8.10. Market Attractiveness/Growth Potential Analysis
8.10.1. By Country
8.10.2. By Product Type
8.10.3. By Application
8.11. North America Plasma Fractionation Demand Share Forecast, 2019-2026
9. Latin America Plasma Fractionation Market Analysis and Forecast
9.1. Introduction
9.1.1. Basis Point Share (BPS) Analysis by Country
9.1.2. Y-o-Y Growth Projections by Country
9.1.3. Latin America Average Pricing Analysis
9.2. Latin America Plasma Fractionation Market Size and Volume Forecast by Country
9.2.1. Brazil
9.2.2. Mexico
9.2.3. Rest of Latin America
9.3. Absolute $ Opportunity Assessment by Country
9.4. Latin America Plasma Fractionation Market Size and Volume Forecast by Applications
9.4.1. Rheumatology
9.4.2.
Hematology
9.4.3.
Immunology
9.4.4.
Neurology
9.5. Basis Point Share (BPS) Analysis by Applications
9.6. Y-o-Y Growth Projections by Applications
9.7. Latin America Plasma Fractionation Market Size and Volume Forecast by End Users
9.7.1. Hospitals & Clinics
9.7.2.
Clinical Research
9.8. Basis Point Share (BPS) Analysis by End Users
9.9. Y-o-Y Growth Projections by End Users
9.10. Market Attractiveness/Growth Potential Analysis
9.10.1. By Country
9.10.2. By Product Type
9.10.3. By Application
9.11. Latin America Plasma Fractionation Demand Share Forecast, 2019-2026
10. Europe Plasma Fractionation Market Analysis and Forecast
10.1. Introduction
10.1.1. Basis Point Share (BPS) Analysis by Country
10.1.2. Y-o-Y Growth Projections by Country
10.1.3. Europe Average Pricing Analysis
10.2. Europe Plasma Fractionation Market Size and Volume Forecast by Country
10.2.1. Germany
10.2.2. France
10.2.3. Italy
10.2.4. U.K.
10.2.5. Spain
10.2.6. Russia
10.2.7. Rest of Europe
10.3. Absolute $ Opportunity Assessment by Country
10.4. Europe Plasma Fractionation Market Size and Volume Forecast by Applications
10.4.1. Rheumatology
10.4.2.
Hematology
10.4.3.
Immunology
10.4.4.
Neurology
10.5. Basis Point Share (BPS) Analysis by Applications
10.6. Y-o-Y Growth Projections by Applications
10.7. Europe Plasma Fractionation Market Size and Volume Forecast by End Users
10.7.1. Hospitals & Clinics
10.7.2.
Clinical Research
10.8. Basis Point Share (BPS) Analysis by End Users
10.9. Y-o-Y Growth Projections by End Users
10.10. Market Attractiveness/Growth Potential Analysis
10.10.1. By Country
10.10.2. By Product Type
10.10.3. By Application
10.11. Europe Plasma Fractionation Demand Share Forecast, 2019-2026
11. Asia Pacific Plasma Fractionation Market Analysis and Forecast
11.1. Introduction
11.1.1. Basis Point Share (BPS) Analysis by Country
11.1.2. Y-o-Y Growth Projections by Country
11.1.3. Asia Pacific Average Pricing Analysis
11.2. Asia Pacific Plasma Fractionation Market Size and Volume Forecast by Country
11.2.1. China
11.2.2. Japan
11.2.3. South Korea
11.2.4. India
11.2.5. Australia
11.2.6. Rest of Asia Pacific (APAC)
11.3. Absolute $ Opportunity Assessment by Country
11.4. Asia Pacific Plasma Fractionation Market Size and Volume Forecast by Applications
11.4.1. Rheumatology
11.4.2.
Hematology
11.4.3.
Immunology
11.4.4.
Neurology
11.5. Basis Point Share (BPS) Analysis by Applications
11.6. Y-o-Y Growth Projections by Applications
11.7. Asia Pacific Plasma Fractionation Market Size and Volume Forecast by End Users
11.7.1. Hospitals & Clinics
11.7.2.
Clinical Research
11.8. Basis Point Share (BPS) Analysis by End Users
11.9. Y-o-Y Growth Projections by End Users
11.10. Market Attractiveness/Growth Potential Analysis
11.10.1. By Country
11.10.2. By Product Type
11.10.3. By Application
11.11. Asia Pacific Plasma Fractionation Demand Share Forecast, 2019-2026
12. Middle East & Africa Plasma Fractionation Market Analysis and Forecast
12.1. Introduction
12.1.1. Basis Point Share (BPS) Analysis by Country
12.1.2. Y-o-Y Growth Projections by Country
12.1.3. Middle East & Africa Average Pricing Analysis
12.2. Middle East & Africa Plasma Fractionation Market Size and Volume Forecast by Country
12.2.1. Saudi Arabia
12.2.2. South Africa
12.2.3. UAE
12.2.4. Rest of Middle East & Africa (MEA)
12.3. Absolute $ Opportunity Assessment by Country
12.4. Middle East & Africa Plasma Fractionation Market Size and Volume Forecast by Applications
12.4.1. Rheumatology
12.4.2.
Hematology
12.4.3.
Immunology
12.4.4.
Neurology
12.5. Basis Point Share (BPS) Analysis by Applications
12.6. Y-o-Y Growth Projections by Applications
12.7. Middle East & Africa Plasma Fractionation Market Size and Volume Forecast by End Users
12.7.1. Hospitals & Clinics
12.7.2.
Clinical Research
12.8. Basis Point Share (BPS) Analysis by End Users
12.9. Y-o-Y Growth Projections by End Users
12.10. Market Attractiveness/Growth Potential Analysis
12.10.1. By Country
12.10.2. By Product Type
12.10.3. By Application
12.11. Middle East & Africa Plasma Fractionation Demand Share Forecast, 2019-2026
13. Competition Landscape
13.1. Global Plasma Fractionation Market: Market Share Analysis
13.2. Plasma Fractionation Distributors and Customers
13.3. Plasma Fractionation Market: Competitive Dashboard
13.4. Company Profiles (Details: Overview, Financials, Developments, Strategy)
13.4.1. Hemarus Therapeutics Limited
13.4.2.
Fusion Healthcare
13.4.3.
Virchow Biotech Private Limited
13.4.4.
PlasmaGen BioSciences Pvt. Ltd.
13.4.5.
ADMA Biologics, Inc.
13.4.6.
Centurion Pharma
13.4.7.
KabaFusion
13.4.8.
Sich