Orthopedic Navigation Systems Market

Orthopedic Navigation Systems Market

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Raksha Sharma

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Vishal Golekar

The global orthopedic navigation software market size was USD 2.41 Bn in 2022 and is likely to reach USD 6.24 Bn by 2031, expanding at a CAGR of 14.5% during 2023 – 2031. The growth of the market is attributed to the increasing prevalence of orthopedic disorders and the rising demand for minimum-invasive surgeries.

Orthopedic navigation systems are advanced medical devices used in orthopedic surgeries to assist surgeons in achieving precise and accurate placement of implants and instruments. The primary purpose of the orthopedic navigation system is to enhance the overall accuracy and effectiveness of surgical procedures by providing detailed and continuous information about the patient’s anatomy. This system is used in various orthopedic surgeries, including joint and hip replacements, spinal procedures, and fracture fixations.

Orthopedic Navigation Systems Market Outlook

The rapid increase in the joint and hip replacement procedure resulting in the high utilization of orthopedic navigation systems during medical surgeries. For instance, as per the report published by the National Library of Medicine, over 1 million hip and knee replacements procedures performed each year in the US.

The COVID-19 pandemic negatively impacted the orthopedic navigation systems market. The outbreak of the pandemic created numerous challenges in the healthcare sector. The primary focus of hospitals and healthcare providers shifted toward COVID-19 patients, which led to the postponement or cancellation of non-essential surgeries. This sudden reduction in surgical volume directly affected the demand for orthopedic navigation systems, as the utilization of these systems is primarily associated with surgical procedures.

Orthopedic Navigation Systems Market Dynamics

Orthopedic Navigation Systems Market Dynamics

Major Drivers

Increasing prevalence of orthopedic disorders among the geriatric population is expected to drive the market during the projected period. Musculoskeletal conditions such as osteoporosis and back pain are the most commonly occurring orthopedic conditions among the elderly population. Furthermore, rising joint replacements and spinal surgeries boost the demand for the orthopedic navigation system, as it improves surgical accuracy and outcomes in surgical procedures.

  • According to the report published by WHO on July 14, 2022, globally around 1.71 billion people are suffering from musculoskeletal conditions. This condition is the leading cause of increasing disability worldwide. Moreover, lower back pain is one of the main contributors to disability among the population of 160 countries. 


The rising demand for minimally invasive orthopedic surgeries is another key driver in the orthopedic navigation system market. The orthopedic device plays a vital role in facilitating minimally invasive procedures by providing real-time visualization and guidance during the surgery. It enables surgeons to make smaller incisions, reduce tissue damage, and enhance the overall efficiency of the surgical process.

Existing Restraints

The high cost associated with implementing an orthopedic navigation system is expected to hinder the market. These systems require high investment in terms of equipment, software, and training. The initial capital expenditure and ongoing maintenance costs can be a barrier for healthcare providers, especially in regions with limited healthcare budgets. The cost factor may limit the widespread adoption of navigation systems, particularly in smaller hospitals and clinics.

Emerging Opportunities

Increasing research activities and the development of advanced technologies are likely to create favorable opportunities for the key players competing in the market. Manufacturers are focusing on developing advanced tracking algorithms, improved visualization techniques, and integration with other surgical technologies such as robotics and artificial intelligence. These navigation systems offer cutting-edge solutions, which allow market players to differentiate themselves and gain a competitive edge in the market.

  • For instance, on March 08, 2023, Augmedics, a pioneer in augmented reality surgical navigation, launched FDA-cleared features in xvision Spine System. These advanced features include artificial intelligence (AI) and customizable view capabilities, which allow surgeons to see patients’ anatomy and accurately navigate instruments during spine procedures.

Scope of Orthopedic Navigation Systems Market Report

The report on the market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.

Attributes

Details

Report Title

Orthopedic Navigation Systems Market - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast

Base Year

2022

Historic Data

2016–2021

Forecast Period

2023–2031

Segmentation

Type (Electromagnetic Localizers, Optical tracking, Fluoroscopy, Magnetic resonance imaging, and Others), Application (Knee Surgery, Spine Surgery, Hip Surgery, Replacement Surgeries, and Others), and End User (Hospitals, Ambulatory Surgical Centers, and Others)

Regional Scope

Asia Pacific, North America, Latin America, Europe, and Middle East & Africa

Report Coverage

Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, and Trends, and Revenue Forecast

Key Players Covered in the Report

Amplitude SAS; Amplitude Surgical; B. Braun SE; Brainlab AG; Medical Device Business Services, Inc. (Depuy Synthes); Fiagon GmbH; GE HealthCare.; Globus Medical; Heal Force; Intellijoint Surgical.; KARL STORZ SE & Co. KG; Kinamed® Incorporated. ; Medtronic; MASMEC S.p.A.; MicroPort Scientific Corporation. ; NuVasive®, Inc.; OrthAlign. ; Orthokey italia SRL; Siemens Healthcare Private Limited ; Smith & Nephew plc; Parsiss Co. ; Stryker; Shenzhen Anke High-tech Co.; and Zimmer Biomet

Orthopedic Navigation Systems Market Segment Insights

Type Segment Analysis

Based on type, the orthopedic navigation systems market is divided into electromagnetic localizers, optical tracking, fluoroscopy, magnetic resonance imaging (MRI), and others. The optical tracking segment is expected to hold a major market share during the projected period, owing to its high accuracy, non-invasive nature, and real-time visualization capabilities.

Optical tracking technology utilizes cameras and infrared markers to track the position and movement of surgical instruments and anatomical landmarks during a procedure. This type of navigation system provides high accuracy and precision in real-time tracking. The cameras capture the movement of markers placed on instruments and patient anatomy, which enables the navigation system to precisely track their position and orientation. This level of accuracy is crucial in orthopedic surgeries where precise instrument placement and alignment are important for successful outcomes.

The magnetic resonance imaging (MRI) segment is anticipated to grow at a significant pace during the projected period, as they provide better imaging of soft tissues contrast than any other imaging technology. This improved imaging solution helps healthcare professionals to differentiate fat, water, muscle, and other soft tissues for accurate diagnosis of various diseases and medical conditions. 

The fluoroscopy is majorly utilized to assists during orthopedic surgery. It has the ability to find out the cause of health problems such as intestinal or heart disease. On the other hand, electromagnetic localizers use magnetic fields to track the surgical tools’ location, which helpful for performing intricate surgical procedures. All these factors are further contributing to market expansion.

Orthopedic Navigation Systems Market Type

Application Segment Analysis

In terms of application, the market is segregated into knee surgery, spine surgery, hip surgery, replacement surgeries, and others. Knee surgery is anticipated to register a robust growth rate during the forecast period, due to the growing number of knee replacement procedures and the rising complexity in knee-related surgeries.

Knee surgeries such as total knee arthroplasty (TKA) or knee replacement are complex procedures that demand high precision and accuracy. Orthopedic navigation systems provide assistance to surgeons in achieving optimal alignment and implant positioning during surgeries. These systems offer real-time feedback and guidance to ensure proper fit, stability, and alignment of the artificial knee components. It further improves patient outcomes and long-term success of the surgery.

  • As per the American Joint Replacement Registry Annual Report 2021, around 2,244,587 primary and revision hip and knee arthroplasties are performed between 2012 to 2020.  

Orthopedic Navigation Systems Market Application

End-user Segment Analysis

Based on end-user, the market is fragmented into hospitals, ambulatory centers, and others. The hospital segment is expected to expand at a high CAGR in the coming years, owing to the availability of specialized orthopedic departments and dedicated surgical units. These departments cater to a large volume of orthopedic patients including those requiring joint replacements, spine surgeries, trauma surgeries, and sports medicine procedures.

Hospitals perform a wide range of orthopedic surgeries, which boosts the demand for advanced navigation systems to support precise surgical planning, execution, and patient care. The collaborative nature of hospitals enables the effective utilization of navigation systems throughout the surgical workflow.

Regional Analysis

In terms of region, the global orthopedic software market is segmented into Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. North America is expected to dominate the market during the projection period, due to the well-established healthcare sector with a strong emphasis on technological advancements and increasing number of knee and hip replacement surgeries. For instance, around 2.2 million surgeries are performed for hip and knee replacements in the US by the end of 2020.

The hospitals and healthcare providers in the region have state-of-the-art infrastructure and the financial capacity to invest in cutting-edge medical technologies. This favorable environment allows for the widespread adoption and utilization of orthopedic navigation systems. Furthermore, the presence of leading players in medical technology and the rising geriatric population at a rapid pace are likely to fuel the market.

The market in Asia Pacific is anticipated to expand at a rapid pace in the coming years, owing to the increasing healthcare spending and the rising prevalence of orthopedic disorders. The growing aging population gives rise to various orthopedic disorders such as osteoarthritis, fractures, and joint degeneration. This demographic trend drives the demand for orthopedic surgeries and subsequently the need for navigation systems to enhance surgical precision and outcomes.

Orthopedic Navigation Systems Market Region

Segments

The global orthopedic software market has been segmented on the basis of

Type

  • Electromagnetic Localizers
  • Optical tracking
  • Fluoroscopy
  • MRI
  • Others

Application

  • Knee Surgery
  • Spine Surgery
  • Hip Surgery
  • Replacement Surgeries
  • Others

End-user

  • Hospitals
  • Ambulatory Surgical Centers
  • Others

Region

  • Asia Pacific
  • North America
  • Latin America
  • Europe
  • Middle East & Africa

Key Players

  • Amplitude SAS
  • Amplitude Surgical
  • B. Braun SE
  • Brainlab AG
  • Medical Device Business Services, Inc. (Depuy Synthes)
  • Fiagon GmbH
  • GE HealthCare.
  • Globus Medical
  • Heal Force
  • Intellijoint Surgical.
  • KARL STORZ SE & Co. KG
  • Kinamed® Incorporated.
  • Medtronic
  • MASMEC S.p.A.
  • MicroPort Scientific Corporation.
  • NuVasive®, Inc.
  • OrthAlign.
  • Orthokey italia SRL
  • Siemens Healthcare Private Limited
  • Smith & Nephew plc
  • Parsiss Co.
  • Stryker
  • Shenzhen Anke High-tech Co.
  • Zimmer Biomet

Competitive Landscape

Key players competing in the global orthopedic software market are Amplitude SAS; Amplitude Surgical; B. Braun SE; Brainlab AG; Medical Device Business Services, Inc. (Depuy Synthes); Fiagon GmbH; GE HealthCare.; Globus Medical; Heal Force; Intellijoint Surgical.; KARL STORZ SE & Co. KG; Kinamed® Incorporated. ; Medtronic; MASMEC S.p.A.; MicroPort Scientific Corporation. ; NuVasive®, Inc.; OrthAlign. ; Orthokey italia SRL; Siemens Healthcare Private Limited ; Smith & Nephew plc; Parsiss Co. ; Stryker; Shenzhen Anke High-tech Co.; and Zimmer Biomet

These companies are boosting their market share by adopting various strategies such as partnerships, mergers, reduction in production costs, launching new products, and implementing advanced technologies.

  • On February 21, 2022, Smith+Nephew, a British multinational medical equipment manufacturing company, launched CORI surgical navigation system. The CORI is a next-generation handheld robotic platform to perform knee arthroplasty with high accuracy, which further improves surgical outcomes. This system is compact and designed to fit in today's crowded operation theaters.

Orthopedic Navigation Systems Market Key Players

1. Executive Summary
2. Assumptions and Acronyms Used
3. Research Methodology
4. Orthopedic Navigation Systems Market Overview
  4.1. Introduction
     4.1.1. Market Taxonomy
     4.1.2. Market Definition
  4.2. Macro-Economic Factors
     4.2.1. Industry Outlook
  4.3. Orthopedic Navigation Systems Market Dynamics
     4.3.1. Market Drivers
     4.3.2. Market Restraints
     4.3.3. Opportunity
     4.3.4. Market Trends
  4.4. Orthopedic Navigation Systems Market - Supply Chain
  4.5. Global Orthopedic Navigation Systems Market Forecast
     4.5.1. Orthopedic Navigation Systems Market Size (US$ Mn) and Y-o-Y Growth
     4.5.2. Orthopedic Navigation Systems Market Size (000’ Units) and Y-o-Y Growth
     4.5.3. Orthopedic Navigation Systems Market Absolute $ Opportunity
5. Global Orthopedic Navigation Systems Market Analysis and Forecast by Types
  5.1. Market Trends
  5.2. Introduction
     5.2.1. Basis Point Share (BPS) Analysis by Types
     5.2.2. Y-o-Y Growth Projections by Types
  5.3. Orthopedic Navigation Systems Market Size and Volume Forecast by Types
     5.3.1. Electromagnetic Localizers
     5.3.2. Optical tracking
     5.3.3. Fluoroscopy
     5.3.4. MRI
     5.3.5. Others
  5.4. Absolute $ Opportunity Assessment by Types
  5.5. Market Attractiveness/Growth Potential Analysis by Types
6. Global Orthopedic Navigation Systems Market Analysis and Forecast by Applications
  6.1. Market Trends
  6.2. Introduction
     6.2.1. Basis Point Share (BPS) Analysis by Applications
     6.2.2. Y-o-Y Growth Projections by Applications
  6.3. Orthopedic Navigation Systems Market Size and Volume Forecast by Applications
     6.3.1. Knee Surgery
     6.3.2. Spine Surgery
     6.3.3. Hip Surgery
     6.3.4. Replacement Surgeries
     6.3.5. Others
  6.4. Absolute $ Opportunity Assessment by Applications
  6.5. Market Attractiveness/Growth Potential Analysis by Applications
7. Global Orthopedic Navigation Systems Market Analysis and Forecast by End Users
  7.1. Market Trends
  7.2. Introduction
     7.2.1. Basis Point Share (BPS) Analysis by End Users
     7.2.2. Y-o-Y Growth Projections by End Users
  7.3. Orthopedic Navigation Systems Market Size and Volume Forecast by End Users
     7.3.1. Hospitals
     7.3.2. Ambulatory Surgical Centers
     7.3.3. Others
  7.4. Absolute $ Opportunity Assessment by End Users
  7.5. Market Attractiveness/Growth Potential Analysis by End Users
8. Global Orthopedic Navigation Systems Market Analysis and Forecast by Region
  8.1. Market Trends
  8.2. Introduction
     8.2.1. Basis Point Share (BPS) Analysis by Region
     8.2.2. Y-o-Y Growth Projections by Region
  8.3. Orthopedic Navigation Systems Market Size and Volume Forecast by Region
     8.3.1. North America
     8.3.2. Latin America
     8.3.3. Europe
     8.3.4. Asia Pacific
     8.3.5. Middle East and Africa (MEA)
  8.4. Absolute $ Opportunity Assessment by Region
  8.5. Market Attractiveness/Growth Potential Analysis by Region
  8.6. Global Orthopedic Navigation Systems Demand Share Forecast, 2019-2026
9. North America Orthopedic Navigation Systems Market Analysis and Forecast
  9.1. Introduction
     9.1.1. Basis Point Share (BPS) Analysis by Country
     9.1.2. Y-o-Y Growth Projections by Country
  9.2. North America Orthopedic Navigation Systems Market Size and Volume Forecast by Country
     9.2.1. U.S.
     9.2.2. Canada
  9.3. Absolute $ Opportunity Assessment by Country
  9.4. North America Orthopedic Navigation Systems Market Size and Volume Forecast by Types
     9.4.1. Electromagnetic Localizers
     9.4.2. Optical tracking
     9.4.3. Fluoroscopy
     9.4.4. MRI
     9.4.5. Others
  9.5. Basis Point Share (BPS) Analysis by Types
  9.6. Y-o-Y Growth Projections by Types
  9.7. North America Orthopedic Navigation Systems Market Size and Volume Forecast by Applications
     9.7.1. Knee Surgery
     9.7.2. Spine Surgery
     9.7.3. Hip Surgery
     9.7.4. Replacement Surgeries
     9.7.5. Others
  9.8. Basis Point Share (BPS) Analysis by Applications
  9.9. Y-o-Y Growth Projections by Applications
  9.10. North America Orthopedic Navigation Systems Market Size and Volume Forecast by End Users
     9.10.1. Hospitals
     9.10.2. Ambulatory Surgical Centers
     9.10.3. Others
  9.11. Basis Point Share (BPS) Analysis by End Users
  9.12. Y-o-Y Growth Projections by End Users
  9.13. Market Attractiveness/Growth Potential Analysis
     9.13.1. By Country
     9.13.2. By Product Type
     9.13.3. By Application
  9.14. North America Orthopedic Navigation Systems Demand Share Forecast, 2019-2026
10. Latin America Orthopedic Navigation Systems Market Analysis and Forecast
  10.1. Introduction
     10.1.1. Basis Point Share (BPS) Analysis by Country
     10.1.2. Y-o-Y Growth Projections by Country
     10.1.3. Latin America Average Pricing Analysis
  10.2. Latin America Orthopedic Navigation Systems Market Size and Volume Forecast by Country
      10.2.1. Brazil
      10.2.2. Mexico
      10.2.3. Rest of Latin America
   10.3. Absolute $ Opportunity Assessment by Country
  10.4. Latin America Orthopedic Navigation Systems Market Size and Volume Forecast by Types
     10.4.1. Electromagnetic Localizers
     10.4.2. Optical tracking
     10.4.3. Fluoroscopy
     10.4.4. MRI
     10.4.5. Others
  10.5. Basis Point Share (BPS) Analysis by Types
  10.6. Y-o-Y Growth Projections by Types
  10.7. Latin America Orthopedic Navigation Systems Market Size and Volume Forecast by Applications
     10.7.1. Knee Surgery
     10.7.2. Spine Surgery
     10.7.3. Hip Surgery
     10.7.4. Replacement Surgeries
     10.7.5. Others
  10.8. Basis Point Share (BPS) Analysis by Applications
  10.9. Y-o-Y Growth Projections by Applications
  10.10. Latin America Orthopedic Navigation Systems Market Size and Volume Forecast by End Users
     10.10.1. Hospitals
     10.10.2. Ambulatory Surgical Centers
     10.10.3. Others
  10.11. Basis Point Share (BPS) Analysis by End Users
  10.12. Y-o-Y Growth Projections by End Users
  10.13. Market Attractiveness/Growth Potential Analysis
     10.13.1. By Country
     10.13.2. By Product Type
     10.13.3. By Application
  10.14. Latin America Orthopedic Navigation Systems Demand Share Forecast, 2019-2026
11. Europe Orthopedic Navigation Systems Market Analysis and Forecast
  11.1. Introduction
     11.1.1. Basis Point Share (BPS) Analysis by Country
     11.1.2. Y-o-Y Growth Projections by Country
     11.1.3. Europe Average Pricing Analysis
  11.2. Europe Orthopedic Navigation Systems Market Size and Volume Forecast by Country
     11.2.1. Germany
     11.2.2. France
     11.2.3. Italy
     11.2.4. U.K.
     11.2.5. Spain
     11.2.6. Russia
     11.2.7. Rest of Europe
  11.3. Absolute $ Opportunity Assessment by Country
  11.4. Europe Orthopedic Navigation Systems Market Size and Volume Forecast by Types
     11.4.1. Electromagnetic Localizers
     11.4.2. Optical tracking
     11.4.3. Fluoroscopy
     11.4.4. MRI
     11.4.5. Others
  11.5. Basis Point Share (BPS) Analysis by Types
  11.6. Y-o-Y Growth Projections by Types
  11.7. Europe Orthopedic Navigation Systems Market Size and Volume Forecast by Applications
     11.7.1. Knee Surgery
     11.7.2. Spine Surgery
     11.7.3. Hip Surgery
     11.7.4. Replacement Surgeries
     11.7.5. Others
  11.8. Basis Point Share (BPS) Analysis by Applications
  11.9. Y-o-Y Growth Projections by Applications
  11.10. Europe Orthopedic Navigation Systems Market Size and Volume Forecast by End Users
     11.10.1. Hospitals
     11.10.2. Ambulatory Surgical Centers
     11.10.3. Others
  11.11. Basis Point Share (BPS) Analysis by End Users
  11.12. Y-o-Y Growth Projections by End Users
  11.13. Market Attractiveness/Growth Potential Analysis
     11.13.1. By Country
     11.13.2. By Product Type
     11.13.3. By Application
  11.14. Europe Orthopedic Navigation Systems Demand Share Forecast, 2019-2026
12. Asia Pacific Orthopedic Navigation Systems Market Analysis and Forecast
  12.1. Introduction
     12.1.1. Basis Point Share (BPS) Analysis by Country
     12.1.2. Y-o-Y Growth Projections by Country
     12.1.3. Asia Pacific Average Pricing Analysis
  12.2. Asia Pacific Orthopedic Navigation Systems Market Size and Volume Forecast by Country
     12.2.1. China
     12.2.2. Japan
     12.2.3. South Korea
     12.2.4. India
     12.2.5. Australia
     12.2.6. Rest of Asia Pacific (APAC)
  12.3. Absolute $ Opportunity Assessment by Country
  12.4. Asia Pacific Orthopedic Navigation Systems Market Size and Volume Forecast by Types
     12.4.1. Electromagnetic Localizers
     12.4.2. Optical tracking
     12.4.3. Fluoroscopy
     12.4.4. MRI
     12.4.5. Others
  12.5. Basis Point Share (BPS) Analysis by Types
  12.6. Y-o-Y Growth Projections by Types
  12.7. Asia Pacific Orthopedic Navigation Systems Market Size and Volume Forecast by Applications
     12.7.1. Knee Surgery
     12.7.2. Spine Surgery
     12.7.3. Hip Surgery
     12.7.4. Replacement Surgeries
     12.7.5. Others
  12.8. Basis Point Share (BPS) Analysis by Applications
  12.9. Y-o-Y Growth Projections by Applications
  12.10. Asia Pacific Orthopedic Navigation Systems Market Size and Volume Forecast by End Users
     12.10.1. Hospitals
     12.10.2. Ambulatory Surgical Centers
     12.10.3. Others
  12.11. Basis Point Share (BPS) Analysis by End Users
  12.12. Y-o-Y Growth Projections by End Users
  12.13. Market Attractiveness/Growth Potential Analysis
     12.13.1. By Country
     12.13.2. By Product Type
     12.13.3. By Application
  12.14. Asia Pacific Orthopedic Navigation Systems Demand Share Forecast, 2019-2026
13. Middle East & Africa Orthopedic Navigation Systems Market Analysis and Forecast
  13.1. Introduction
     13.1.1. Basis Point Share (BPS) Analysis by Country
     13.1.2. Y-o-Y Growth Projections by Country
     13.1.3. Middle East & Africa Average Pricing Analysis
  13.2. Middle East & Africa Orthopedic Navigation Systems Market Size and Volume Forecast by Country
     13.2.1. Saudi Arabia
     13.2.2. South Africa
     13.2.3. UAE
     13.2.4. Rest of Middle East & Africa (MEA)
  13.3. Absolute $ Opportunity Assessment by Country
  13.4. Middle East & Africa Orthopedic Navigation Systems Market Size and Volume Forecast by Types
     13.4.1. Electromagnetic Localizers
     13.4.2. Optical tracking
     13.4.3. Fluoroscopy
     13.4.4. MRI
     13.4.5. Others
  13.5. Basis Point Share (BPS) Analysis by Types
  13.6. Y-o-Y Growth Projections by Types
  13.7. Middle East & Africa Orthopedic Navigation Systems Market Size and Volume Forecast by Applications
     13.7.1. Knee Surgery
     13.7.2. Spine Surgery
     13.7.3. Hip Surgery
     13.7.4. Replacement Surgeries
     13.7.5. Others
  13.8. Basis Point Share (BPS) Analysis by Applications
  13.9. Y-o-Y Growth Projections by Applications
  13.10. Middle East & Africa Orthopedic Navigation Systems Market Size and Volume Forecast by End Users
     13.10.1. Hospitals
     13.10.2. Ambulatory Surgical Centers
     13.10.3. Others
  13.11. Basis Point Share (BPS) Analysis by End Users
  13.12. Y-o-Y Growth Projections by End Users
  13.13. Market Attractiveness/Growth Potential Analysis
     13.13.1. By Country
     13.13.2. By Product Type
     13.13.3. By Application
  13.14. Middle East & Africa Orthopedic Navigation Systems Demand Share Forecast, 2019-2026
14. Competition Landscape
  14.1. Global Orthopedic Navigation Systems Market: Market Share Analysis
  14.2. Orthopedic Navigation Systems Distributors and Customers
  14.3. Orthopedic Navigation Systems Market: Competitive Dashboard
  14.4. Company Profiles (Details: Overview, Financials, Developments, Strategy)
     14.4.1. Amplitude SAS
     14.4.2. Amplitude Surgical
     14.4.3. B. Braun SE
     14.4.4. Brainlab AG
     14.4.5. Medical Device Business Services, Inc. (Depuy Synthes)
     14.4.6. Fiagon GmbH
     14.4.7. GE HealthCare.
     14.4.8. Globus Medical
     14.4.9. Heal Force
     14.4.10. Intellijoint Surgical.
     14.4.11. KARL STORZ SE & Co. KG
     14.4.12. Kinamed® Incorporated.
     14.4.13. Medtronic
     14.4.14. MASMEC S.p.A.
     14.4.15. MicroPort Scientific Corporation.
     14.4.16. NuVasive®, Inc.
     14.4.17. OrthAlign.
     14.4.18. Orthokey italia SRL
     14.4.19. Siemens Healthcare Private Limited
     14.4.20. Smith & Nephew plc
     14.4.21. Parsiss Co.
     14.4.22. Stryker
     14.4.23. Shenzhen Anke High-tech Co.
     14.4.24. Zimmer Biomet

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