The global nattokinase market was valued at USD 29.5 Million in 2019 and is projected to reach USD 35.5 Million by 2027, expanding at a CAGR of 2.6% during the forecast period. Demand for nattokinase is driven by the surging number of chronic diseases due to changing lifestyles and lack of physical activity, rising consumer awareness regarding health, increasing demand for plant source supplements, and growing prevalence of cardiovascular diseases.
Nattokinase is a natural source enzyme found in natto, a soy-based traditional Japanese dish. Bacillus subtilis, a particular bacterium, produces this nattokinase enzyme during the fermentation process of natto. When bacteria are used to ferment soybeans, it activates nattokinase, which has a cheese-like flavor and contains various health benefits. Natto is a nutritious breakfast meal. It fulfills customer needs for a healthy product at a less cost, particularly in Japan. Nattokinase is only found in natto and is purchased as a supplement. Natto is high in vitamins, protein, and minerals. Nattokinase is as effective as natto food.
Nattokinase dissolves blood clots, which helps to preserve normal blood vessel structure, enhance blood flow, and reduce the risk of heart. It helps lower blood pressure, which reduces strain on the heart and reduces the risk of heart attacks. Nattokinase helps to maintain a healthy bacterial balance in the gut, generally known as microbiome. Poor gut health weakens the immune system and raises the risk of developing diabetes, obesity, rheumatoid arthritis, cancer, and heart disease, among other chronic conditions. Nattokinase's probiotic characteristics help to regulate and prevent metabolic problems including obesity and diabetes by boosting metabolism and reducing body fat.
Nattokinase is a food-based product that occurs naturally. Nattokinase are available in various forms such as liquid, and powder. It has a long-lasting effect and is proven to be effective without causing negative effects. It is used to treat pain, fibromyalgia, CFS, endometriosis, uterine fibroids, muscle spasms, infertility, cancer, and beriberi, which is a vitamin-deficient condition.
Increasing number of chronic diseases such as cancer, diabetes, and strokes, due to changing lifestyles and lack of physical exercise is expected to drive the market during the forecast period. Nattokinase is used as a dietary supplement and a functional food and helps to reduce cholesterol level in the body. Lack of physical activity leads to obesity, type 2 diabetes, some types of cancer, cardiovascular disease, and early death. Consumption of nattokinase helps reduce prevalence of chronic diseases.
Rising consumer awareness regarding health is anticipated to propel the market in the coming years. Population in developed and developing countries has several health concerns. Nattokinase is a natural supplement that is consumed orally, has a well-established safety profile, is cost-effective, and has specific advantages over other medicines. Consumers are becoming health-conscious and trying health and dietary supplements. Nattokinase is easily available in the form of tablets, powder, and liquid in various supermarkets as well as on e-commerce websites.
Increasing demand for plant-based supplements is expected to boost the nattokinase market during the forecast period. Rapid growth of vegan and vegetarian population across the world plays a major role in increasing the demand for plant-based supplements. Nattokinase is a plant-based supplement, as it is extracted from soybean-based dish, natto and is safe, effective, and low in cost for the treatment of heart and circulatory disease.
Increasing prevalence of cardiovascular diseases including hypertension, heart disease, stroke, high cholesterol, deep vein thrombosis (DVT), and chest pain (angina) are estimated to drive the market during the forecast period. In the treatment of cardiovascular diseases (CVD), nattokinase acts as a promising alternative. Nattokinase breaks blood clots, which aids in the maintenance of a healthy blood vessel structure, increases blood flow, and reduces the risk of heart diseases. Nattokinase supplements contain antihypertensive, anti-atherosclerotic, and lipid-lowering properties, as well as antiplatelet, and neuroprotective properties, which helps reduce the risk of cardiovascular diseases.
Special precautions/warning and side effects of nattokinase include its function as a "blood thinner" and bleeding issues. Blood pressure is expected to be reduced by nattokinase, which acts as a concern if blood pressure is already too low. Nattokinase is expected to raise concerns for pregnant women or while breastfeeding. Additionally, lack of credible information about nattokinase is expected to hinder the market growth during the forecast period.
Less research data on long-term effects of nattokinase is anticipated to restrain the growth of the market during the forecast period. Nattokinase is used for the treatment of many chronic diseases such as cancer, diabetes, seasonal allergies such as sinus infections, and blood clots, but there is limited research data related to effectiveness of nattokinase for all these diseases.
Governments of many countries are conducting various health awareness programmes related to consumption of plant-based supplements, which is expected to create opportunities in the coming years. Governments of several countries are expected to establish a plant system for large-scale production of nattokinase, which creates opportunities for key players.
Companies are adopting various strategies for development of nattokinase, which is anticipated to create huge prospects in the market. Fermentation of nattokinase is studied extensively using a variety of methods. Companies are using several strategies to use nattokinase in various applications such as snack bars, soft chews, or drinks.
The Coronavirus disease 2019 (COVID-19) pandemic highlighted global interdependence, economic disparities, and governance challenges. From a business point of view, COVID-19 is significantly limiting economic activities, especially in the consumer sector. Approximately 95 percent of people across the globe are on stay-at-home orders, due to COVID 19, which is reducing consumer spending across a wide range of categories. However, demand for health supplements increased, due to rising awareness about general health and wellbeing.
Manufacturing processes in various industries such as automotive, aerospace, and consumer electronics were not affected before COVID-19. Demand for nattokinase was growing at a rapid pace, while its supply chain was not hampered. The outbreak of COVID-19 put huge stress on the nattokinase market across the globe. The pandemic affected all businesses and GDP fell significantly.
People are concentrating on buying daily needs products, instead of health supplements, as per capita income reduced along with GDP. Demand for nattokinase is projected to depend on the rising demand for health supplements and consumer awareness regarding health. Post COVID-19 pandemic, the demand for nattokinase is anticipated to return to normality, which is expected to lead to the recovery of demand for nattokinase.
In terms of applications, the nattokinase market is divided into food, dietary supplement, and cosmetic. The food segment is expected to expand at a significant pace during the forecast period, due to rising consumer awareness associated with various health benefits of nattokinase food, as it helps in preventing bad cholesterol, improve immunity system, and helps to strengthen bones.
The dietary supplement segment is projected to grow at a rapid pace, owing to increasing prevalence of several cardiovascular diseases, including heart disease, stroke, hypertension, high cholesterol, deep vein thrombosis (DVT), and chest pain (angina). The working population across the globe is failing to reach daily nutrient requirements, due to hectic work schedules and changing lifestyles.
This is raising the demand for dietary supplements to meet nutrient requirements due to high convenience, which is anticipated to boost the market over the forecast period. Factors such as rising demand for natural and organic cosmetics and increasing concerns about health and safety are anticipated to drive the demand for the cosmetic segment.
Based on distribution channel, the nattokinase market is categorized as online and offline. The online segment is projected to expand at a considerable pace during the forecast period, due to rising number of internet users, increasing penetration of the internet across the globe, and favorable rules and regulations by the government to support online businesses. COVID-19 resulted in a surge in e-commerce amid slowing economic activity. Online shopping is the process where consumers buy goods, services, and other items directly from sellers through the Internet without the need for an intermediary provider.
Shoppers access web retailers from the comfort of their homes. Nattokinase food products and supplements are widely available on various e-commerce platforms in the form of powder, tablets, and liquid. Factors such as rising internet usage, increasing smartphone users, and rapid expansion of the e-commerce industry is expected to boost the market during the forecast period.
As lockdowns became the new normal, businesses and customers gradually went digital, providing and purchasing goods and services on the internet, increasing the share of world retail trade in e-commerce from 14% in 2019 to almost 17% in 2020. The offline segment is projected to grow at a significant pace in the coming years, due to increasing number of hypermarkets and supermarkets in developed and developing countries. Increasing sales through supermarkets/hypermarkets is attributed to availability of a wide range of products and high discounts on offline channels.
On the basis of regions, the global nattokinase market is fragmented into North America, Europe, Latin America, Asia Pacific, and Middle East & Africa. North America is expected to dominate the market during the forecast period, due to such as increasing hypertensive population and rising prevalence of chronic diseases, owing to changing lifestyles.
Moreover, increasing consumer awareness associated with the health benefits of nattokinase in this region, is expected to fuel the demand for nattokinase supplements in the region. The US holds a significant share of the market during the forecast period. Increasing prevalence of cardiovascular diseases, growing expenditure by key players, rising regulatory approvals, and increasing seasonal allergies such as blood clots and sinus are the major driving factors for the market in the country.
Europe holds a substantial share of the market during the forecast period, due to local presence of various leading companies. The market in Europe matured, due to increasing prevalence of cardiovascular diseases and increasing cases of stroke, leading to significant growth in the region in terms of revenue. Initiatives by governments to increase health awareness is expected to drive the market. Various manufacturers are currently offering different forms of nattokinase such as powder, and tablets which is further fueling the nattokinase market.
Key Benefits for Industry Participants & Stakeholders
- In-depth analysis of the global nattokinase market
- Historical, current, and projected market size in terms of value (USD million) and volume (tons)
- Potential & niche segments and regions exhibiting promising growth covered
- Industry drivers, restraints, and opportunities covered in the study
- Recent industry trends and developments
- Competitive landscape & strategies of key players
By Distribution Channel
- Dietary Supplement
Key Market Players Profiled in the Report
- North America
- Asia Pacific
- Latin America
- Middle East & Africa
- Infinita Biotech Private Limited.
- Japan Bio Science Laboratory
- Sungen Bioscience Co.,Ltd
- PHARMANAGER INGREDIENTS
- NutraCap Labs
- Contek Life Science Co., Ltd.
- BIOVEN INGREDIENTS
- RAJVI ENTERPRISE
- Belle Chemical
- GeneFerm Biotechnology Co., Ltd.
- Hexon Laboratories Private Limited
- Xi'an Herb Bio-Tech Co.Ltd
- Prominent manufacturers operating in the global nattokinase market include GeneFerm Biotechnology Co., Ltd., Japan Bio Science Laboratory CO. Ltd, Belle Chemical, Sungen Bioscience Co.,Ltd, Infinita Biotech Private Limited., PHARMANAGER INGREDIENTS, Contek Life Science Co., Ltd., BIOVEN INGREDIENTS, RAJVI ENTERPRISE, Hexon Laboratories Private Limited, Xi'an Herb Bio-Tech Co.Ltd, and NutraCap Labs.
- These companies are considered as key manufacturers of nattokinase based on their revenue, research & development (R&D) activities, regional presence, and supply chain management system. Moreover, these companies hold various certifications such as International Organization for Standardization, Halal India, Kosher Badatz Shatz, GMP Certification, ASI Food Safety, HACCP HXQC, and USDA Organic.
- In July 2020, Sungen Bioscience Co., Ltd and Shenyang Pharmaceutical University signed an agreement to develop a new form of biologic nattokinase oral preparation and injection.