Dental Bone Graft Substitutes Market Trends, Industry | 2031

Report Description

The global dental bone graft substitutes market size was USD 0.75 Bn in 2022 and is likely to reach USD 1.4 Bn by 2031, expanding at a CAGR of 9.5% during 2023–2031. Increasing number of dental implant surgeries and rising incidence of bone diseases including bone tumors and infections are likely to boost the market.

Increasing popularity of dental implant surgeries due to their longevity and dependability is expected to boost the dental bone graft substitutes market. Advanced surgical techniques such as bone regeneration and bone graft are resulting in a higher success rate of dental implant surgeries. In addition, the growing prevalence of bone infections and bone tumors and the number of orthopedic surgeries across the world are expected to fuel the dental bone graft substitute market during the assessment period.

• According to the National Institutes of Health (NIH), nearly 5 million implant surgeries are performed in the US every year. The study suggests that around 90% to 95% is the success rate of implants over the last 10 years.

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The market report finds that the COVID-19 pandemic hampered the dental bone graft substitute market, owing to the decline in elective surgeries. People avoided visiting dental clinics and hospitals due to lockdown and movement restrictions, which decreased the market. As the healthcare sector was burdened by COVID-19, the non-essential care and dental clinics were closed, which considerably reduced dental surgeries and bone surgeries and significantly affected the market.

• On March 23, 2020, American Dental Association (ADA) Health Policy Institute survey stated that around 76% of dental clinics in the US were closed, however, emergency services were only allowed. Around 5% of dental clinics were open but operating on a lower volume of patients due to lockdowns.

Dental Bone Graft Substitutes Market Dynamics

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Major Drivers

Increasing prevalence of dental disorders is expected to boost the dental bone graft substitutes market. Oral diseases are a major health burden for several countries and affect people throughout their lifetime. Oral disorders can lead to significant discomfort, causing pain, disfigurement, and even death.

Dental caries (or tooth decay) in permanent teeth is the most common health condition. It occurs due to various risk factors common to noncommunicable diseases (NCDs), including poor hygiene, consumption of sugar, alcohol, tobacco, and their primary, social, and commercial determinants.

• As per the World Health Organization (WHO) Oral Health Status Report 2022, oral disease affects around 3.5 billion individuals worldwide, with 3 out of 4 people affected belonging to middle-income countries. The report further estimated that around 2 billion of the global population suffer from dental caries in permanent teeth and around 514 million children suffer from primary teeth dental caries.

Rising geriatric population suffering from dental-related disorders is anticipated to fuel the dental bone graft substitute market. Older adults are at bigger risk for root caries, due to the increasing use of medications that produce xerostomia and increased gingival recession that discloses root surfaces.

• According to the Centers for Disease Control and Prevention (CDC), approximately all adults (96%) aged 65 years and above have a cavity, and 1 in 5 have untreated tooth decay. Approximately 1 in 5 adults have lost all their teeth. Adults 75 years of age and older (26%) were likely to have complete tooth loss twice compared with adults aged 65 to 74 years (13%).

Existing Restraints

High cost of surgical treatments due to the higher price of graft materials, implants, membranes, and replacements hinders the dental bone graft substitute market. Dental implants, oral surgery, veneers, orthodontics, and dental crowns are the most expensive dental procedures. In addition, the lack of proper reimbursement policies is anticipated to hamper the market. Medical insurance policies do not cover dental procedures such as dental implants in various countries around the world.

Emerging Opportunities

Rising adoption of new technologies by several companies for the development of innovative bone graft substitutes is expected to create lucrative opportunities for the market players. The popularity of allografts is increasing, due to the requirement of a single incision for the implantation of allografts, which requires two incisions.

Rising demand for xenografts and synthetic bone grafts, owing to the benefits such as low chances of infection at the site and high stability is expected to boost the market in the coming years. Synthetic materials adoption is increasing among healthcare establishments in developed countries, owing to their chemical composition similar to human bone.

• On April 26, 2022, The Aspen Group announced a multi-year strategic partnership with ACE Surgical Group for bone grafting solutions. ACE surgical group supports the Aspen Group with a wide range of membrane and bone grafting solutions.

• On January 14, 2020, OrthoPediatrics Corp. introduced a bone graft substitute in the US called QucikPack. It is a fully bone graft substitute introducing a viscosity, calcium phosphate cement, which carefully mimics the mineral phase of natural bone.

Scope of Dental Bone Graft Substitutes Market Report

The market report includes an assessment of the market trends, market segments, and regional markets. Overview and dynamics have also been included in the report.

Dental Bone Graft Substitutes Market Segment Insights

Product Type Segment Analysis

Based on product type, the dental bone graft substitutes market is divided into allografts, xenografts, synthetic bone grafts, and others. The synthetic bone grafts segment is expected to expand at a significant pace during the projection period, due to the increasing technological advancements, rising prevalence of bone-related disorders, and high demand for synthetic products.

Synthetic bone grafts are made from a wide range of materials including ceramics, polymers, bioglasses, composites, and metals. Several key players in the market are focusing to develop new products, which have been precisely engineered with unique properties in bone formation, which is further expected to drive the market.

• On March 22, 2022, Molecular Matrix, Inc. launched Osteo-P Synthetic Bone Graft Substitute (BGS) for use in the musculoskeletal system. Osteo-P BGS is made from MMI’s hyper-crosslinked carbohydrate polymer (HCCP) technology, which can be engineered to enhance the microenvironment for bone regeneration and repair.

The xenografts segment is anticipated to hold a key share of the market in the coming years, owing to the reduced morbidity, easy availability, sterility, and long shelf life.  The most common xenograft source material in dentistry is deproteinized bovine bone. Several commercially available xenograft options are Bio-Oss Collagen, Bio-Oss, and Pepgen-P15, among others. Many key players in the market are developing new xenograft products, as it is the most affordable, which is propelling the segment growth.

• In March 2022, Fredun Pharmaceuticals Limited obtained approval from the Central Drugs Standard Control Organization (CDSCO) for developing Xenografts for several orthopedic and dental surgical appliances in India. The company aims to penetrate the Dental fraternity across India.

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Product Segment Analysis

On the basis of product, the global market is segregated into osteograft, Bio OSS, grafton, and others. The Bio OSS segment is projected to register a considerable CAGR during the forecast period, due to the high implant survival rates. Bio OSS is an allergic-free bone replacement material of bovine origin, equivalent to human bone. It is used to repair bone defects and to reconstruct ridge configurations. A deproteinized bovine bone is used in dentistry for bone extension procedures, owing to its osteoconductive properties.

Application Segment Analysis

Based on application, the dental bone graft substitutes market is segmented into ridge augmentation, socket preservation, periodontal defect regeneration, and others. The socket preservation segment is expected to register a robust growth rate during the forecast period, due to the increasing awareness about oral care and rising dental implant procedures. Socket preservation is a helpful treatment to prevent bone resorption after atraumatic extraction, with the use of appropriate biomaterials and membranes.

The ridge augmentation segment is anticipated to account for a major market share in the coming years, owing to the increasing demand for dental implant procedures. A ridge augmentation is performed in the area of missing teeth or tooth. It helps to recreate the shape of the jaw and reduces the possibility of the jawbone becoming deformed or misshapen. Ridge augmentation techniques have become more effective and minimally invasive. This, as a result, is increasing the demand for ridge augmentations with the help of new materials and techniques.

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Mechanism Segment Analysis

On the basis of mechanism, the global market is classified into osteoinduction, osteopromotion, osteoconduction, and osteogenesis. The osteoinduction segment is projected to expand at a significant growth rate during the projection period. The process of inducing osteogenesis is called osteoinduction, which is commonly observed during bone healing. Osteoinduction involves using immature cells to stimulate their growth into preosteoblasts.

End-user Segment Analysis

Based on end-user, the dental bone graft substitutes market is categorized as hospitals, dental clinics, research institutes, and others. The hospitals segment is expected to hold the dominant market share during the forecast period, owing to the increasing number of cosmetic dentistry procedures performed in hospitals. The segment growth is further attributed to the growing geriatric population and the rising number of patients visiting hospitals.

The dental clinics segment is anticipated to account for a significant market share in the coming years, owing to the easy availability of surgeons and the increasing number of dental graft surgeries. Private dental clinics or specialty clinics have a wider presence and primarily have skilled doctors specializing in bone grafting procedures. Emerging countries such as China and India, are focusing on developing medical facilities such as specialty clinics to accommodate a large patient pool. Such growth in the healthcare infrastructure is expected to boost the segment.

Regional Analysis

In terms of region, the global dental bone graft substitutes market is classified as Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. Europe is expected to dominate the market during the projection period, due to the supportive government regulations for product commercialization. The regional market growth is further attributed to the increasing geriatric population, rising governmental spending on oral healthcare, and increasing advancements in technology and materials. For instance,

• On November 29, 2022, Lithoz, an Austria-based company developed a new LithaBone HA 480, a highly enhanced ceramic material for 3D-printed bone replacements. It was developed in an intensive partnership with earlier Lithoz bone graft substitute users.

The market in North America is anticipated to expand at a rapid pace in the coming years, owing to the increasing number of visits to dental clinics, rising healthcare costs, and the availability of an advanced healthcare system. In addition, an increasing number of strategic initiatives such as acquisitions, product launches, mergers, and developments among the market key players are expected to boost the market in the region.

• According to the Centers for Disease Control and Prevention (CDC), among adolescents aged 12 to 19, around 57% of individuals have a cavity in their permanent teeth. Whereas, around 90% of adults aged 20 and above have at least one cavity. 1 in 4 adults between 20 and 64 years of age has at least one cavity.

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