Global Bacillus Subtilis Market by Forms, (Liquid, Powder, and Paste) by Product Types, (<100 billion CFU/g, 100–300 billion CFU/g, > 300 billion CFU/g), by End Use Industry (Pharmaceutical Industry, Food & Beverage Industry, Agriculture Industry, Livestock Industry, and Others), and by Regions (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast 2020 – 2027
Bacillus Subtilis Market Market Outlook:
The global bacillus subtilis market was valued at USD 71.2 Million in 2019 and is projected to reach USD 125.9 Million by 2027, expanding at a CAGR of 7.8% during the forecast period. Bacillus subtilis is a fast-growing gram-positive aerobic bacterium and is found in soil and water. The rod-shaped cells are usually 2–6 µm in length and slightly less than 1 µm in diameter.
The optimal growth temperature is between 30-35°C and the doubling time is only 20 minutes. Under certain growth conditions, cells tend to form long chains, which are connected by unbroken wall material. Under starvation conditions, cells undergo a complex process of cell differentiation, leading to the formation of endospores, which are released through cell membrane lysis, stem cell.
Vegetative cells are mobile. They form biofilms and "fruiting bodies" of spores. Bacillus subtilis releases a variety of enzymes to break down various substrates and enables bacteria to survive in a constantly changing environment. B. subtilis has a long history and was first described in the 19th century. This bacterium was originally called Vibrio subtilis and discovered in 1835 by Christian Gottfried Ehrenberg.
It is first described in detail and renamed in 1872 by Ferdinand Cohn. This bacterium is now known as Bacillus subtilis. Experiments in the late 1950s confirmed its position in the history of genetics and experiments showed that it used linear DNA for natural transformation.
Bacillus Subtilis Market Market Dynamics
Beneficial in combating infections
Bacteriocin from Bacillus subtilis inhibits the growth of various pathogens. Bacillus subtilis reduces the incidence of respiratory infections in the elderly. Bacillus subtilis, isolated from soil, shows antibacterial activity against pathogenic human Candida albicans.
Metabolites of bacillus subtilis reduce the resistance of pathogenic urogenital tract microbiota to antibiotics in patients with urinary tract infections, thereby speeding up their recovery. It reduces the symptoms of clostridium difficile infection in mice.
B. subtilis inhibits infection and enteropathy in suckling mice infected with C. rodentium. Hence, the benefits of bacillus subtills in combating infections in humans and animals is driving the market during the forecast period.
Increasing demand for Bacillus Subtilis due to its anti-oxidant properties
Bacillus subtilis has protective and anti-oxidant activity against DNA. A signal molecule from Bacillus subtilis induces the heat shock protein, Hsp27 in mammalian cells, which protects intestinal cells from oxidant-mediated tissue damage and loss of barrier function.
Anti-oxidant properties benefit humans undergoing stress-related activities. Hence, increasing demand for bacillus subtilis, due to its anti-oxidant properties, is driving the market during the forecast period.
Lack of awareness among consumers about the effectiveness of Bacillus Subtilis
Various beneficial properties are associated with bacillus subtilis, which have a positive impact on humans, animals, and plants. It helps in reducing stress levels, increases immunity, improves liver disorders, and reduces the risk of cancer in humans. It helps in preventing nausea, vomiting, abdominal pain, and diarrhea.
Most people do not know about these benefits, which reduces the demand for B. subtilis and adversely affects the sales. Hence, lack of consumer awareness about bacillus subtilis hampers the market growth during the forecast period.
Increasing Investments in Bacillus Subtilis-based product development
Companies are adopting various strategies to gain competitive advantages. Key players are focusing on product development, which increases the demand for bacillus subtilis. BASF SE launched a new product range, named Velondis, which is a biofungicide seed treatment agent, which was registered with the US Environmental Protection Agency (EPA) in January 2018.
Velondis incorporates a unique stain of Bacillus subtilis, which protects seedlings and plants from soil-borne diseases. Deerland Enzymes, Inc. introduced a new, more soluble probiotic strain, Bacillus subtilis DE111. This spore-forming probiotic is easily soluble in natural foods and used in hot beverages, functional drinks, and dietary supplements.
Bacillus subtilis has multiple health benefits for humans, animals, and plants and thus it is an attractive probiotic species for various clinical conditions. It is used as an important ingredient in many industries such as pharmaceutical, food & beverage, livestock, wastewater management, agriculture, and industrial chemical.
Governments around the globe have issued various rules and regulations for the registration, production, and use of bacillus subtilis. For production various precautionary measures are adopted to reduce the risk of adverse effects on the workers. Bacillus subtilis strains are used as antigen that carry bacterial vaccines and cells to produce antigens.
Bacillus Subtilis Market Segmental Outlook
By Type Segment
Based on forms, the global bacillus subtilis market is divided into liquid, powder, and paste. Liquid bacillus subtilis is used in the food & beverage industry, the pharmaceutical industry, and the bio-chemical industry. Bacillus subtilis powder is used in the agriculture industry and as cattle feeding. Bacillus subtilis paste is used in the bio-chemical industry.
By Product Types Segment
In terms of product types, the global bacillus subtilis market is classified into <100 billion CFU/g, 100–300 billion CFU/g, and > 300 billion CFU/g. The effectiveness of probiotics is expressed in CFU or colony-forming unit, which is a unit of measurement used in microbiology to estimate the number of bacteria that can divide and form colonies in a sample, although most positive clinical studies indicate a probiotic dose of 10 to 20 billion CFU per day is enough to maintain a healthy digestive system and immunity, and 50 to 100 billion CFU products are becoming more common. Bacillus subtilis products are measured in billion CFU/g.
By End Use Industry Segment
In terms of End Use Industry, the global bacillus subtilis market is classified into pharmaceutical, food & beverage, agriculture, livestock, and others. The food & beverage industry is expected to hold a significant market share during the forecast period owing to its various health benefits such as improved liver disorder, reduced risk of cancer, protection against infections and allergies, and decreased obesity.
Bacillus Subtilis Market Region Wise Outlook
Based on regions, the global bacillus subtilis market is fragmented into North America, Europe, Latin America, and Middle East & Africa. Growing demand for high-purity Bacillus subtilis in countries such as Japan, China, and India have led to the substantial growth of the Bacillus subtilis market in Asia Pacific.
Probiotic beverage formulations containing Bacillus subtilis are popular in South Korea and Japan. Latin America and the Middle East & Africa are expected to hold a significant share of the market during the forecast period.
The demand for Bacillus subtilis is expected to rise in key industries such as pharmaceuticals, food processing, and beverages in these regions. Increasing demand for non-toxic bacterial products and changes in consumer preferences that are estimated to fuel the demand for Bacillus subtilis in the near future.
Key Benefits for Industry Participants & Stakeholders
- In-depth Analysis of the Global Bacillus Subtilis Market
- Historical, Current and Projected Market Size in terms of Value
- Potential & Niche Segments and Regions Exhibiting Promising Growth Covered
- Industry Drivers, Restraints and Opportunities Covered in the Study
- Recent Industry Trends and Developments
- Competitive Landscape & Strategies of Key Players
- Neutral Perspective on Global Bacillus Subtilis Market Performance
Video Summary for Bacillus Subtilis Market Market :
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Chapter 2 Assumptions and Acronyms Used
Chapter 3 Research Methodology
Chapter 4 Bacillus Subtilis Market Overview
4.1 Introduction
4.1.1 Market Taxonomy
4.1.2 Market Definition
4.1.3 Macro-Economic Factors Impacting the Market Growth
4.2 Bacillus Subtilis Market Dynamics
4.2.1 Market Drivers
4.2.2 Market Restraints
4.2.3 Market Opportunity
4.3 Bacillus Subtilis Market - Supply Chain Analysis
4.3.1 List of Key Suppliers
4.3.2 List of Key Distributors
4.3.3 List of Key Consumers
4.4 Key Forces Shaping the Bacillus Subtilis Market
4.4.1 Bargaining Power of Suppliers
4.4.2 Bargaining Power of Buyers
4.4.3 Threat of Substitution
4.4.4 Threat of New Entrants
4.4.5 Competitive Rivalry
4.5 Global Bacillus Subtilis Market Size & Forecast, 2017-2027
4.5.1 Bacillus Subtilis Market Size and Y-o-Y Growth
4.5.2 Bacillus Subtilis Market Absolute $ Opportunity
4.6 Global Bacillus Subtilis Market: Impact Of Key Regulations
4.7 Technology Trends
Chapter 5 Global Bacillus Subtilis Market Analysis and Forecast By Form
5.1 Introduction
5.1.1 Key Market Trends & Growth Opportunities By Form
5.1.2 Basis Point Share (BPS) Analysis By Form
5.1.3 Absolute $ Opportunity Assessment By Form
5.2 Bacillus Subtilis Market Size Forecast By Form
5.2.1 Liquid
5.2.2 Powder
5.2.3 Paste
5.3 Market Attractiveness Analysis By Form
Chapter 6 Global Bacillus Subtilis Market Analysis and Forecast By Product Type
6.1 Introduction
6.1.1 Key Market Trends & Growth Opportunities By Product Type
6.1.2 Basis Point Share (BPS) Analysis By Product Type
6.1.3 Absolute $ Opportunity Assessment By Product Type
6.2 Bacillus Subtilis Market Size Forecast By Product Type
6.2.1 <100 billion CFU/g
6.2.2 100–300 billion CFU/g
6.2.3 > 300 billion CFU/g
6.3 Market Attractiveness Analysis By Product Type
Chapter 7 Global Bacillus Subtilis Market Analysis and Forecast By Application
7.1 Introduction
7.1.1 Key Market Trends & Growth Opportunities By Application
7.1.2 Basis Point Share (BPS) Analysis By Application
7.1.3 Absolute $ Opportunity Assessment By Application
7.2 Bacillus Subtilis Market Size Forecast By Application
7.2.1 Pharmaceutical Industry
7.2.2 Food & Beverage Industry
7.2.3 Agriculture Industry
7.2.4 Livestock Industry
7.2.5 Others
7.3 Market Attractiveness Analysis By Application
Chapter 8 Global Bacillus Subtilis Market Analysis and Forecast by Region
8.1 Introduction
8.1.1 Key Market Trends & Growth Opportunities by Region
8.1.2 Basis Point Share (BPS) Analysis by Region
8.1.3 Absolute $ Opportunity Assessment by Region
8.2 Bacillus Subtilis Market Size Forecast by Region
8.2.1 North America
8.2.2 Europe
8.2.3 Asia Pacific
8.2.4 Latin America
8.2.5 Middle East & Africa (MEA)
8.3 Market Attractiveness Analysis by Region
Chapter 9 Coronavirus Disease (COVID-19) Impact
9.1 Introduction
9.2 Current & Future Impact Analysis
9.3 Economic Impact Analysis
9.4 Government Policies
9.5 Investment Scenario
Chapter 10 North America Bacillus Subtilis Analysis and Forecast
10.1 Introduction
10.2 North America Bacillus Subtilis Market Size Forecast by Country
10.2.1 U.S.
10.2.2 Canada
10.3 Basis Point Share (BPS) Analysis by Country
10.4 Absolute $ Opportunity Assessment by Country
10.5 Market Attractiveness Analysis by Country
10.6 North America Bacillus Subtilis Market Size Forecast By Form
10.6.1 Liquid
10.6.2 Powder
10.6.3 Paste
10.7 Basis Point Share (BPS) Analysis By Form
10.8 Absolute $ Opportunity Assessment By Form
10.9 Market Attractiveness Analysis By Form
10.10 North America Bacillus Subtilis Market Size Forecast By Product Type
10.10.1 <100 billion CFU/g
10.10.2 100–300 billion CFU/g
10.10.3 > 300 billion CFU/g
10.11 Basis Point Share (BPS) Analysis By Product Type
10.12 Absolute $ Opportunity Assessment By Product Type
10.13 Market Attractiveness Analysis By Product Type
10.14 North America Bacillus Subtilis Market Size Forecast By Application
10.14.1 Pharmaceutical Industry
10.14.2 Food & Beverage Industry
10.14.3 Agriculture Industry
10.14.4 Livestock Industry
10.14.5 Others
10.15 Basis Point Share (BPS) Analysis By Application
10.16 Absolute $ Opportunity Assessment By Application
10.17 Market Attractiveness Analysis By Application
Chapter 11 Europe Bacillus Subtilis Analysis and Forecast
11.1 Introduction
11.2 Europe Bacillus Subtilis Market Size Forecast by Country
11.2.1 Germany
11.2.2 France
11.2.3 Italy
11.2.4 U.K.
11.2.5 Spain
11.2.6 Russia
11.2.7 Rest of Europe
11.3 Basis Point Share (BPS) Analysis by Country
11.4 Absolute $ Opportunity Assessment by Country
11.5 Market Attractiveness Analysis by Country
11.6 Europe Bacillus Subtilis Market Size Forecast By Form
11.6.1 Liquid
11.6.2 Powder
11.6.3 Paste
11.7 Basis Point Share (BPS) Analysis By Form
11.8 Absolute $ Opportunity Assessment By Form
11.9 Market Attractiveness Analysis By Form
11.10 Europe Bacillus Subtilis Market Size Forecast By Product Type
11.10.1 <100 billion CFU/g
11.10.2 100–300 billion CFU/g
11.10.3 > 300 billion CFU/g
11.11 Basis Point Share (BPS) Analysis By Product Type
11.12 Absolute $ Opportunity Assessment By Product Type
11.13 Market Attractiveness Analysis By Product Type
11.14 Europe Bacillus Subtilis Market Size Forecast By Application
11.14.1 Pharmaceutical Industry
11.14.2 Food & Beverage Industry
11.14.3 Agriculture Industry
11.14.4 Livestock Industry
11.14.5 Others
11.15 Basis Point Share (BPS) Analysis By Application
11.16 Absolute $ Opportunity Assessment By Application
11.17 Market Attractiveness Analysis By Application
Chapter 12 Asia Pacific Bacillus Subtilis Analysis and Forecast
12.1 Introduction
12.2 Asia Pacific Bacillus Subtilis Market Size Forecast by Country
12.2.1 China
12.2.2 Japan
12.2.3 South Korea
12.2.4 India
12.2.5 Australia
12.2.6 South East Asia (SEA)
12.2.7 Rest of Asia Pacific (APAC)
12.3 Basis Point Share (BPS) Analysis by Country
12.4 Absolute $ Opportunity Assessment by Country
12.5 Market Attractiveness Analysis by Country
12.6 Asia Pacific Bacillus Subtilis Market Size Forecast By Form
12.6.1 Liquid
12.6.2 Powder
12.6.3 Paste
12.7 Basis Point Share (BPS) Analysis By Form
12.8 Absolute $ Opportunity Assessment By Form
12.9 Market Attractiveness Analysis By Form
12.10 Asia Pacific Bacillus Subtilis Market Size Forecast By Product Type
12.10.1 <100 billion CFU/g
12.10.2 100–300 billion CFU/g
12.10.3 > 300 billion CFU/g
12.11 Basis Point Share (BPS) Analysis By Product Type
12.12 Absolute $ Opportunity Assessment By Product Type
12.13 Market Attractiveness Analysis By Product Type
12.14 Asia Pacific Bacillus Subtilis Market Size Forecast By Application
12.14.1 Pharmaceutical Industry
12.14.2 Food & Beverage Industry
12.14.3 Agriculture Industry
12.14.4 Livestock Industry
12.14.5 Others
12.15 Basis Point Share (BPS) Analysis By Application
12.16 Absolute $ Opportunity Assessment By Application
12.17 Market Attractiveness Analysis By Application
Chapter 13 Latin America Bacillus Subtilis Analysis and Forecast
13.1 Introduction
13.2 Latin America Bacillus Subtilis Market Size Forecast by Country
13.2.1 Brazil
13.2.2 Mexico
13.2.3 Rest of Latin America (LATAM)
13.3 Basis Point Share (BPS) Analysis by Country
13.4 Absolute $ Opportunity Assessment by Country
13.5 Market Attractiveness Analysis by Country
13.6 Latin America Bacillus Subtilis Market Size Forecast By Form
13.6.1 Liquid
13.6.2 Powder
13.6.3 Paste
13.7 Basis Point Share (BPS) Analysis By Form
13.8 Absolute $ Opportunity Assessment By Form
13.9 Market Attractiveness Analysis By Form
13.10 Latin America Bacillus Subtilis Market Size Forecast By Product Type
13.10.1 <100 billion CFU/g
13.10.2 100–300 billion CFU/g
13.10.3 > 300 billion CFU/g
13.11 Basis Point Share (BPS) Analysis By Product Type
13.12 Absolute $ Opportunity Assessment By Product Type
13.13 Market Attractiveness Analysis By Product Type
13.14 Latin America Bacillus Subtilis Market Size Forecast By Application
13.14.1 Pharmaceutical Industry
13.14.2 Food & Beverage Industry
13.14.3 Agriculture Industry
13.14.4 Livestock Industry
13.14.5 Others
13.15 Basis Point Share (BPS) Analysis By Application
13.16 Absolute $ Opportunity Assessment By Application
13.17 Market Attractiveness Analysis By Application
Chapter 14 Middle East & Africa (MEA) Bacillus Subtilis Analysis and Forecast
14.1 Introduction
14.2 Middle East & Africa (MEA) Bacillus Subtilis Market Size Forecast by Country
14.2.1 Saudi Arabia
14.2.2 South Africa
14.2.3 UAE
14.2.4 Rest of Middle East & Africa (MEA)
14.3 Basis Point Share (BPS) Analysis by Country
14.4 Absolute $ Opportunity Assessment by Country
14.5 Market Attractiveness Analysis by Country
14.6 Middle East & Africa (MEA) Bacillus Subtilis Market Size Forecast By Form
14.6.1 Liquid
14.6.2 Powder
14.6.3 Paste
14.7 Basis Point Share (BPS) Analysis By Form
14.8 Absolute $ Opportunity Assessment By Form
14.9 Market Attractiveness Analysis By Form
14.10 Middle East & Africa (MEA) Bacillus Subtilis Market Size Forecast By Product Type
14.10.1 <100 billion CFU/g
14.10.2 100–300 billion CFU/g
14.10.3 > 300 billion CFU/g
14.11 Basis Point Share (BPS) Analysis By Product Type
14.12 Absolute $ Opportunity Assessment By Product Type
14.13 Market Attractiveness Analysis By Product Type
14.14 Middle East & Africa (MEA) Bacillus Subtilis Market Size Forecast By Application
14.14.1 Pharmaceutical Industry
14.14.2 Food & Beverage Industry
14.14.3 Agriculture Industry
14.14.4 Livestock Industry
14.14.5 Others
14.15 Basis Point Share (BPS) Analysis By Application
14.16 Absolute $ Opportunity Assessment By Application
14.17 Market Attractiveness Analysis By Application
Chapter 15 Competition Landscape
15.1 Bacillus Subtilis Market: Competitive Dashboard
15.2 Global Bacillus Subtilis Market: Market Share Analysis, 2020
15.3 Company Profiles (Details – Overview, Financials, Developments, Strategy)
15.3.1 AgriLife
15.3.2 Anand Agro Care
15.3.3 Aumgene Biosciences
15.3.4 BASF SE
15.3.5 Bayer AG
15.3.6 Deerland Probiotics & Enzymes, Inc
15.3.7 Lonza
15.3.8 Manidharma Biotech Private Limited
15.3.9 Merck KGaA
15.3.10 Meteoric Biopharmaceuticals Pvt. Ltd.
15.3.11 Real IPM UK
15.3.12 Wuhan Kernel Bio-tech Co., Ltd.