Genome Editing Market by Technology (TALEN, ZFN, CRISPR, and Others), Application (Genetic Engineering, Drug Discovery, Gene-modified Cell Therapy, Diagnostics, Cell Line Engineering, and Others), End-user (Biotechnology & Pharma Companies, Contract Research Organization, Academics & Government Institutes, and Others), and Region (Asia Pacific, North America, Latin America, Europe, and Middle East & Africa) - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast 2023 – 2031
The global genome editing market size was USD 4,811.06 Mn in 2022 and is likely to reach USD 36,060.96 Mn by 2031, expanding at a CAGR of 22.31% during 2023–2031. Increasing number of genomics projects and rising production of genetically modified crops are anticipated to boost the market during the forecast period.
Genome editing is known as gene editing that involves group of technologies that allows researchers to change the DNA of an organism. This method allows alteration, addition, or removal of genes from specific locations of genome. It has application in cell line development in which cell lines are improved for considerable expression of therapeutic proteins with desired post translational modification. Furthermore, yeast cells were genetically modified to improve the production of biofuels. Crops and plants are genetically modified to enhance yield and harvest.
CRISPR-Cas9 is one of the advanced techniques used in genome editing. It is CRISPR-associated protein9 and short for regularly clustered regularly interspaced short palindrome repeats. Researcher believes that it is a rapid, cheap, and more efficient method compared to existing genome editing methods. Genome engineering has now become a potential transformative diagnostic tool, which is used by various government research centers for oncology studies.
The research report finds that the COVID-19 pandemic impacted the expansion of the genome editing market during the forecast period. Molecular biology tools including DETECTR, CARVER, PAC-MAN, ASO, CRISPR-Cas12/13-based SHERLOCK, ribozymes, aptamers, antisense peptide nucleic acids, and RNAi silencing therapies turn out to be more efficient than conventional treatment methods during the pandemic. Moreover, genome-wide association studies are new technique for discovering genes that are involved in human disease.
Genome Editing Market Dynamics
Major Drivers
Rising government funding is expected to drive the market in the coming years. Governments in several countries are investing in the field of genomics, which play a major role in the advancements of new technologies in genome editing. This investments and funding support the government institutes and academics to conduct various genome editing and engineering related projects. Genome editing technologies are helpful in managing rare diseases such as sickle-cell diseases and HIV.
In March 2020, the Ministry of Innovation, Science, and Industry (Science) invested USD 15 million for 11 genomic research projects in the agriculture, health, and environment sectors through Genome Canada. USD 29.7 million were invested by businesses, research partners, and regional government. These projects include the research on cervical and ovarian cancer.
Existing Restraints
High cost of genomic equipment and ethical concerns related to genetic research is projected to hamper the market expansion in the coming years. Genomic equipment has advanced functionalities and features, and thus the price of the equipment range between USD 10 to 20 million. High investments in multiple genomics instruments are not feasible for small and medium sized enterprises.
Emerging Opportunities
Increasing use of genome editing in personalized medicine is anticipated to create lucrative opportunities for market players. Medical practitioners identify medicine and treatment needs of patients with the help of personalized medicine. Personalized medicine is cost-effective and offers improved patient compliance, early detection of disease, and optimize various therapies.
Scope of the Genome Editing Market Report
The market report includes an assessment of the market trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes |
Details |
Report Title |
Genome Editing Market - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast |
Base Year |
2022 |
Historic Data |
2016–2021 |
Forecast Period |
2023–2031 |
Segmentation |
Technology (TALEN, ZFN, CRISPR, and Others), Application (Genetic Engineering, Drug Discovery, Gene-modified Cell Therapy, Diagnostics, Cell Line Engineering, and Others), and End-user (Biotechnology & Pharma Companies, Contract Research Organization, Academics & Government Institutes, and Others) |
Regional Scope |
Asia Pacific, North America, Latin America, Europe, and Middle East & Africa |
Report Coverage |
Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, Market Trends, and Revenue Forecast |
Key Players Covered in the Report |
Agilent Technologies; GenScript; Horizon Discovery Limited; Lonza; Merck and Thermo Fisher Scientific; CRISPR Therapeutics; Danaher; Integrated DNA Technologies, Inc.; Eurofins Scientific; and Editas Medicine |
Genome Editing Market Segment Insights
On the basis of technology, the genome editing market is segmented into TALEN, ZFN, CRISPR, and others. The CRISPR segment is projected to expand at a considerable CAGR during the forecast period, as it is used to generate chimeric antigen receptor T cells that are used to treat cancer. These T cells are extracted from patients and then treated to express chimeric antigen receptors before reinjecting into the body. Moreover, CRISPR/Cas9 treats thalassemia and sickle cell disease. The demand for CRISPR/Cas9 is increasing due to the enhanced efficiency of CRISPR/Cas9 in the identification and investigation of genetic disorders and drug discovery. The TALEN segment is anticipated to account for a major market share during the forecast period. TALEN is used to modify plant genomes to create cost-effective and nutritious food products.
Based on application, the market is divided into genetic engineering, drug discovery, gene-modified cell therapy, diagnostics, cell line engineering, and others. The gene-modified cell therapy segment is expected to hold a significant share of the market in the coming years, due to the increasing incidence of genetic disorders in several countries. Mutations and changes in the DNA sequence of an individual cause genetic diseases. Human genome editing methods are used on germline and somatic cells. Advanced genome editing techniques based on proteins include meganucleases, transcription activator-like effector nucleases (TALENs), and zinc-finger nucleases (ZFNs). The drug discovery segment accounts for a significant market share, owing to the rising technological advancements and high-grade equipment.
The cell line engineering segment is projected to register a considerable CAGR in the coming years, as it is used extensively in vaccine development, protein synthesis, drug development, and artificial tissue generation. Genetic mutations that cause diseases are corrected with the help of pluripotent stem cells (iPSCs) obtained through cell line engineering.
On the basis of end-user, the market is segregated into biotechnology & pharma companies, contract research organization, academics & government institutes, and others. The biotechnology & pharma companies segment is anticipated to expand at a substantial CAGR during the forecast period, due to the rising prevalence of infectious diseases and cancer. The biotech and pharma companies focused on producing genetically modified seeds and animals to maximize agricultural productivity. The academics & government institutes segment is expected to hold a significant share of the market in the coming years, owing to the increasing funding for genetic research.
In terms of region, the global genome editing market is classified as Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. North America is expected to dominate the global market during the forecast period, owing to rising use of genetically modified crops and presence of research grants in the region. The market in Asia Pacific is anticipated to expand at a rapid pace during the forecast period, due to the rising government initiatives and surging research and development activities on gene therapy in the region.
2. Assumptions and Acronyms Used
3. Research Methodology
4. Genome Editing Market Overview
4.1. Introduction
4.1.1. Market Taxonomy
4.1.2. Market Definition
4.2. Macro-Economic Factors
4.2.1. Industry Outlook
4.3. Genome Editing Market Dynamics
4.3.1. Market Drivers
4.3.2. Market Restraints
4.3.3. Opportunity
4.3.4. Market Trends
4.4. Genome Editing Market - Supply Chain
4.5. Global Genome Editing Market Forecast
4.5.1. Genome Editing Market Size (US$ Mn) and Y-o-Y Growth
4.5.2. Genome Editing Market Size (000’ Units) and Y-o-Y Growth
4.5.3. Genome Editing Market Absolute $ Opportunity
5. Global Genome Editing Market Analysis and Forecast by Applications
5.1. Market Trends
5.2. Introduction
5.2.1. Basis Point Share (BPS) Analysis by Applications
5.2.2. Y-o-Y Growth Projections by Applications
5.3. Genome Editing Market Size and Volume Forecast by Applications
5.3.1. Genetic Engineering
5.3.2. Drug Discovery
5.3.3. Gene-modified Cell Therapy
5.3.4. Diagnostics
5.3.5. Cell Line Engineering
5.3.6. Others
5.4. Absolute $ Opportunity Assessment by Applications
5.5. Market Attractiveness/Growth Potential Analysis by Applications
6. Global Genome Editing Market Analysis and Forecast by End Users
6.1. Market Trends
6.2. Introduction
6.2.1. Basis Point Share (BPS) Analysis by End Users
6.2.2. Y-o-Y Growth Projections by End Users
6.3. Genome Editing Market Size and Volume Forecast by End Users
6.3.1. Biotechnology & Pharma Companies
6.3.2. Contract Research Organization
6.3.3. Academics & Government Institutes
6.3.4. Others
6.4. Absolute $ Opportunity Assessment by End Users
6.5. Market Attractiveness/Growth Potential Analysis by End Users
7. Global Genome Editing Market Analysis and Forecast by Region
7.1. Market Trends
7.2. Introduction
7.2.1. Basis Point Share (BPS) Analysis by Region
7.2.2. Y-o-Y Growth Projections by Region
7.3. Genome Editing Market Size and Volume Forecast by Region
7.3.1. North America
7.3.2. Latin America
7.3.3. Europe
7.3.4. Asia Pacific
7.3.5. Middle East and Africa (MEA)
7.4. Absolute $ Opportunity Assessment by Region
7.5. Market Attractiveness/Growth Potential Analysis by Region
7.6. Global Genome Editing Demand Share Forecast, 2019-2026
8. North America Genome Editing Market Analysis and Forecast
8.1. Introduction
8.1.1. Basis Point Share (BPS) Analysis by Country
8.1.2. Y-o-Y Growth Projections by Country
8.2. North America Genome Editing Market Size and Volume Forecast by Country
8.2.1. U.S.
8.2.2. Canada
8.3. Absolute $ Opportunity Assessment by Country
8.4. North America Genome Editing Market Size and Volume Forecast by Applications
8.4.1. Genetic Engineering
8.4.2. Drug Discovery
8.4.3. Gene-modified Cell Therapy
8.4.4. Diagnostics
8.4.5. Cell Line Engineering
8.4.6. Others
8.5. Basis Point Share (BPS) Analysis by Applications
8.6. Y-o-Y Growth Projections by Applications
8.7. North America Genome Editing Market Size and Volume Forecast by End Users
8.7.1. Biotechnology & Pharma Companies
8.7.2. Contract Research Organization
8.7.3. Academics & Government Institutes
8.7.4. Others
8.8. Basis Point Share (BPS) Analysis by End Users
8.9. Y-o-Y Growth Projections by End Users
8.10. Market Attractiveness/Growth Potential Analysis
8.10.1. By Country
8.10.2. By Product Type
8.10.3. By Application
8.11. North America Genome Editing Demand Share Forecast, 2019-2026
9. Latin America Genome Editing Market Analysis and Forecast
9.1. Introduction
9.1.1. Basis Point Share (BPS) Analysis by Country
9.1.2. Y-o-Y Growth Projections by Country
9.1.3. Latin America Average Pricing Analysis
9.2. Latin America Genome Editing Market Size and Volume Forecast by Country
9.2.1. Brazil
9.2.2. Mexico
9.2.3. Rest of Latin America
9.3. Absolute $ Opportunity Assessment by Country
9.4. Latin America Genome Editing Market Size and Volume Forecast by Applications
9.4.1. Genetic Engineering
9.4.2. Drug Discovery
9.4.3. Gene-modified Cell Therapy
9.4.4. Diagnostics
9.4.5. Cell Line Engineering
9.4.6. Others
9.5. Basis Point Share (BPS) Analysis by Applications
9.6. Y-o-Y Growth Projections by Applications
9.7. Latin America Genome Editing Market Size and Volume Forecast by End Users
9.7.1. Biotechnology & Pharma Companies
9.7.2. Contract Research Organization
9.7.3. Academics & Government Institutes
9.7.4. Others
9.8. Basis Point Share (BPS) Analysis by End Users
9.9. Y-o-Y Growth Projections by End Users
9.10. Market Attractiveness/Growth Potential Analysis
9.10.1. By Country
9.10.2. By Product Type
9.10.3. By Application
9.11. Latin America Genome Editing Demand Share Forecast, 2019-2026
10. Europe Genome Editing Market Analysis and Forecast
10.1. Introduction
10.1.1. Basis Point Share (BPS) Analysis by Country
10.1.2. Y-o-Y Growth Projections by Country
10.1.3. Europe Average Pricing Analysis
10.2. Europe Genome Editing Market Size and Volume Forecast by Country
10.2.1. Germany
10.2.2. France
10.2.3. Italy
10.2.4. U.K.
10.2.5. Spain
10.2.6. Russia
10.2.7. Rest of Europe
10.3. Absolute $ Opportunity Assessment by Country
10.4. Europe Genome Editing Market Size and Volume Forecast by Applications
10.4.1. Genetic Engineering
10.4.2. Drug Discovery
10.4.3. Gene-modified Cell Therapy
10.4.4. Diagnostics
10.4.5. Cell Line Engineering
10.4.6. Others
10.5. Basis Point Share (BPS) Analysis by Applications
10.6. Y-o-Y Growth Projections by Applications
10.7. Europe Genome Editing Market Size and Volume Forecast by End Users
10.7.1. Biotechnology & Pharma Companies
10.7.2. Contract Research Organization
10.7.3. Academics & Government Institutes
10.7.4. Others
10.8. Basis Point Share (BPS) Analysis by End Users
10.9. Y-o-Y Growth Projections by End Users
10.10. Market Attractiveness/Growth Potential Analysis
10.10.1. By Country
10.10.2. By Product Type
10.10.3. By Application
10.11. Europe Genome Editing Demand Share Forecast, 2019-2026
11. Asia Pacific Genome Editing Market Analysis and Forecast
11.1. Introduction
11.1.1. Basis Point Share (BPS) Analysis by Country
11.1.2. Y-o-Y Growth Projections by Country
11.1.3. Asia Pacific Average Pricing Analysis
11.2. Asia Pacific Genome Editing Market Size and Volume Forecast by Country
11.2.1. China
11.2.2. Japan
11.2.3. South Korea
11.2.4. India
11.2.5. Australia
11.2.6. Rest of Asia Pacific (APAC)
11.3. Absolute $ Opportunity Assessment by Country
11.4. Asia Pacific Genome Editing Market Size and Volume Forecast by Applications
11.4.1. Genetic Engineering
11.4.2. Drug Discovery
11.4.3. Gene-modified Cell Therapy
11.4.4. Diagnostics
11.4.5. Cell Line Engineering
11.4.6. Others
11.5. Basis Point Share (BPS) Analysis by Applications
11.6. Y-o-Y Growth Projections by Applications
11.7. Asia Pacific Genome Editing Market Size and Volume Forecast by End Users
11.7.1. Biotechnology & Pharma Companies
11.7.2. Contract Research Organization
11.7.3. Academics & Government Institutes
11.7.4. Others
11.8. Basis Point Share (BPS) Analysis by End Users
11.9. Y-o-Y Growth Projections by End Users
11.10. Market Attractiveness/Growth Potential Analysis
11.10.1. By Country
11.10.2. By Product Type
11.10.3. By Application
11.11. Asia Pacific Genome Editing Demand Share Forecast, 2019-2026
12. Middle East & Africa Genome Editing Market Analysis and Forecast
12.1. Introduction
12.1.1. Basis Point Share (BPS) Analysis by Country
12.1.2. Y-o-Y Growth Projections by Country
12.1.3. Middle East & Africa Average Pricing Analysis
12.2. Middle East & Africa Genome Editing Market Size and Volume Forecast by Country
12.2.1. Saudi Arabia
12.2.2. South Africa
12.2.3. UAE
12.2.4. Rest of Middle East & Africa (MEA)
12.3. Absolute $ Opportunity Assessment by Country
12.4. Middle East & Africa Genome Editing Market Size and Volume Forecast by Applications
12.4.1. Genetic Engineering
12.4.2. Drug Discovery
12.4.3. Gene-modified Cell Therapy
12.4.4. Diagnostics
12.4.5. Cell Line Engineering
12.4.6. Others
12.5. Basis Point Share (BPS) Analysis by Applications
12.6. Y-o-Y Growth Projections by Applications
12.7. Middle East & Africa Genome Editing Market Size and Volume Forecast by End Users
12.7.1. Biotechnology & Pharma Companies
12.7.2. Contract Research Organization
12.7.3. Academics & Government Institutes
12.7.4. Others
12.8. Basis Point Share (BPS) Analysis by End Users
12.9. Y-o-Y Growth Projections by End Users
12.10. Market Attractiveness/Growth Potential Analysis
12.10.1. By Country
12.10.2. By Product Type
12.10.3. By Application
12.11. Middle East & Africa Genome Editing Demand Share Forecast, 2019-2026
13. Competition Landscape
13.1. Global Genome Editing Market: Market Share Analysis
13.2. Genome Editing Distributors and Customers
13.3. Genome Editing Market: Competitive Dashboard
13.4. Company Profiles (Details: Overview, Financials, Developments, Strategy)
13.4.1. Agilent Technologies
13.4.2. GenScript
13.4.3. Horizon Discovery Limited
13.4.4. Lonza
13.4.5. Merck and Thermo Fisher Scientific
13.4.6. CRISPR Therapeutics
13.4.7. Danaher
13.4.8. Eurofins Scientific
13.4.9. Editas Medicine