Two-Photon Microscopy Market

Global Two-Photon Microscopy Market By Product (Microscope, Software, and Accessories), By Type (In Vivo and In Vitro) By Application (Material Science, Nanotechnology, Life Science, Semiconductors, and Others) and Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa)

  • Report ID: HC-68
  • Author: Growth Market Reports
  • Rating: 4.8
  • Total Reviews: 15
  • No. Of Pages: 186
  • Format:
  • Pub. Date: 2020-10-12
  • Share:

Market Outlook:

The global two-photon microscopy market was valued at USD 127.2 Million in 2019 and is projected to reach USD 185.1 Million by 2027, expanding at a CAGR of 5.2% during the forecast period. Two-photon microscopy stated to as two-photon laser scanning microscopy, is an improvement of accuracy fluorescence microscopy. In confocal or epifluorescent microscopy, a single photon of light at a specified wavelength causes the fluorophore to release light. In two-photon microscopy, the fluorophore can be activated by efficiently absorbing two-photons concurrently. In this case, each photon itself has a wavelength that is double the normal wavelength of excitation, and has half the energy level per photon. Once the fluorophore consumes the two low-energy photons around the same moment, each adds half of the excitation energy required to communicate with the fluorophore, as it has been hit by a single photon of more energy and a short wavelength.

Global Two-Photon Microscopy Market Key Takeaways

Increasing emphasis on nanotechnology, favorable government policies, and funding are driving the growth of the two-photon microscopy market. Furthermore, technical advances, such as super-resolution microscopy and high-throughput techniques, are boosting the demand for two-photon microscopy. Conversely, high cost of multiphoton microscopes and the regulatory duty limits the development and the demand for multiphoton microscopes. Moreover, increasing funding, extended deadlines for clinical trial findings, rising number of R&D activities for two-photon microscopy is projected to fuel the market growth.

Major advantages of this microscopy is that the near-simultaneous advent of two-photons is an exceedingly unusual occurrence; therefore, excitement of fluorescence is confined to a small plane of focus within the specimen. This technique offers better images than conventional confocal microscopy, even in situations where relatively few fluorophores are involved and photons are released from the excited fluorophores located on the focal plane. Therefore, all the light that is produced can be stored. Fluorophores above and below the focal plane are not operated enough to create any fluorescent background.

Market Dynamics
Major established players dominate the market, thus creating hindrances for new players. The introduction of two-photon microscopy, helps companies cater to several consumers and increases their market presence. Opportunities for new players to enter the market are low due to high initial investment and strict regulation pertaining to two-photon microscopy manufacturing. Less availability of raw materials due to pandemic and increased R&D for manufacturing of two-photon microscopes are expected to increase the bargaining power of suppliers. Buyers have access to refurbished products, as most of the two-photon microscopes and their accessories can be reused; therefore, the bargaining power of buyers is moderate.

The exact substitution of two-photon is currently unavailable in the market; however, other microscopic techniques such as confocal and three-photon microscopy techniques are being used by several end-users. This, reduces the growth of two-photon microscopy among conventional end-users. The software of two-photon microscopy is trending among end-users due to their highly efficient outcomes with the requirement of less efforts and manpower.

Rising Focus on Nanotechnology
Nanomaterials provide lightweight and efficient components for applications in the automobile and building industries. Nanotechnology in coatings makes surface products durable, water-resistant, and stain-resistant, thus providing options for high street fashion and high-end athletic equipment in the clothing industry. Many high-performance electronic devices depend on nanotechnology, for example, Quantum Dot (QD) technology for LED displays and smartphones (QDs provide high quality and reliable color reproduction). Global investment in nanotechnology is expected to be equivalent to USD 4 trillion. Out of which China and the US together are spending more than USD 2 billion during the forecast period. Growing emphasis on nanotechnology research, which is heavily financed by private enterprises and governments, facilitates the procurement of sophisticated automated microscopes by numerous research institutes. This, in turn, is projected to boost the two-photon microscopy market rapidly during the forecast period.

Increasing Application Areas of Two-photon Microscopy
Scientists have been improving microscopes ever since the devices were invented in the late sixteenth century, and have accelerated significantly over the past decade. The infrared excitation light which is used in the two-photon microscopy is not as much harmful to the biological samples; with UV-excitable fluorophores than those utilizing UV light. Two-photon microscopy has allowed for a greater understanding of these processes within living cells. Technological advancements proven in current applications of the two-proton microscopy have led to faster imaging of embryos, comprising those of zebra fish and fruit flies while maintaining viability. Each microscope technique involves a compromise. Many advances have been made using these microscopy tools. The two-photon microscopy is used in many industrial applications such as automotive, machinery, and water treatment. Hence, increasing application of two-photon microscopy is estimated to boost the market during the forecast period.

Segmental Outlook

On the basis of products, the two-photon microscopy market is segmented into microscope, software, and accessories. The microscope segment is expected to hold a significant share of the market due to growing applications and high demand for technologically advanced magnification devices, while the accessories segment is projected to expand at a significant CAGR during the forecast period.

Global Two-Photon Microscopy Market By Product

Based on types, the two-photon microscopy market is bifurcated into in vivo and in vitro. The in vitro segment is projected to constitute 57.9% share of the market by 2027 and is anticipated to expand at a CAGR of 5.3%, as it is commonly preferred for high incidence chronic and infectious diseases drug production.

Global Two-Photon Microscopy Market By Type

In terms of applications, the two-photon microscopy market is classified as material science, nanotechnology, life science, semiconductors, and others. The life science segment holds a major share of the market and is projected to expand at a substantial CAGR during the forecast period, as a majority of two-photon microscopy is utilized by this segment. The nanotechnology segment is expected to drive the demand for two-photon microscopy owing to the increasing research in nanomaterials during the forecast period.

Regional Outlook

In terms of regions, the global two-photon microscopy market has been fragmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is a promising region for the market. The market is this region constituted 42.0% share of the global market in 2020. The market in Asia Pacific is projected to expand at a CAGR of 5.7% due to the increase in government spending, rising awareness about two-photon microscopy, and growing consumer base in the region.

Global Two-Photon Microscopy Market By Region

Competitive Landscape

  • Key players in the market include Bruker, Leica Microsystems, Nikon Instruments Inc., OLYMPUS CORPORATION, and ZEISS International. They are considered as key manufacturers in this market based on their investments in R&D, segmental revenue, regional presence, and supply chain management system.
  • The players are adopting key strategies such as acquisition, and geographical expansion where potential opportunity for the two-photon microscopy is added in the company’s capacity.
  • For instance, In November 2018, Bruker introduced next-generation wide-field, multi-photon microscope for opto-genetics. This New Ultima 2Pplus which delivers versatile and advanced 3d photo stimulation and full-field imaging for neurobiology.
  • In September 2020, Nikon Instruments Inc. has announced the launch of NIS-Elements Clarify.ai, a new addition to Nikon’s on the rise suite of artificial intelligence tools for microscopy.

Global Two-Photon Microscopy Market By Manufacturer

Key Benefits for Industry Participants & Stakeholders

  • In-depth Analysis of the Global Two-Photon Microscopy Market
  • Historical, Current and Projected Market Size in terms of Value
  • Potential & Niche Segments and Regions Exhibiting Promising Growth Covered
  • Industry Drivers, Restraints and Opportunities Covered in the Study
  • Recent Industry Trends and Developments
  • Competitive Landscape & Strategies of Key Players
  • Neutral Perspective on Global Two-Photon Microscopy Market Performance
Chapter 1 Executive Summary
Chapter 2 Assumptions and Acronyms Used
Chapter 3 Research Methodology
Chapter 4 Two-Photon Microscopy Market Overview
   4.1 Introduction
      4.1.1 Market Taxonomy
      4.1.2 Market Definition
   4.2 Macro-Economic Factors

      4.2.1 Industry Outlook
   4.3 Two-Photon Microscopy Market Dynamics
      4.3.1 Market Drivers
      4.3.2 Market Restraints
      4.3.3 Market Opportunity

      4.3.4 Market Trends
   4.4 Two-Photon Microscopy Market - Supply Chain Analysis
      4.4.1 List of Key Suppliers
      4.4.2 List of Key Distributors
      4.4.3 List of Key Consumers
   4.5 Global Two-Photon Microscopy Market Size & Forecast, 2017-2027
      4.5.1 Two-Photon Microscopy Market Size and Y-o-Y Growth
      4.5.2 Two-Photon Microscopy Market Absolute $ Opportunity
Chapter 5 Global Two-Photon Microscopy Market Analysis and Forecast By Product
   5.1 Introduction
      5.1.1 Key Market Trends & Growth Opportunities By Product
      5.1.2 Basis Point Share (BPS) Analysis By Product
      5.1.3 Absolute $ Opportunity Assessment By Product
   5.2 Two-Photon Microscopy Market Size Forecast By Product
      5.2.1 Microscope
      5.2.2 Software
      5.2.3 Accessories
   5.3 Market Attractiveness Analysis By Product
Chapter 6 Global Two-Photon Microscopy Market Analysis and Forecast By Type
   6.1 Introduction
      6.1.1 Key Market Trends & Growth Opportunities By Type
      6.1.2 Basis Point Share (BPS) Analysis By Type
      6.1.3 Absolute $ Opportunity Assessment By Type
   6.2 Two-Photon Microscopy Market Size Forecast By Type
      6.2.1 In Vivo
      6.2.2 In Vitro
   6.3 Market Attractiveness Analysis By Type
Chapter 7 Global Two-Photon Microscopy Market Analysis and Forecast By Application
   7.1 Introduction
      7.1.1 Key Market Trends & Growth Opportunities By Application
      7.1.2 Basis Point Share (BPS) Analysis By Application
      7.1.3 Absolute $ Opportunity Assessment By Application
   7.2 Two-Photon Microscopy Market Size Forecast By Application
      7.2.1 Material Science
      7.2.2 Nanotechnology
      7.2.3 Life Science
      7.2.4 Semiconductors
      7.2.5 Others
   7.3 Market Attractiveness Analysis By Application
Chapter 8 Global Two-Photon Microscopy Market Analysis and Forecast by Region
   8.1 Introduction
      8.1.1 Key Market Trends & Growth Opportunities by Region
      8.1.2 Basis Point Share (BPS) Analysis by Region
      8.1.3 Absolute $ Opportunity Assessment by Region
   8.2 Two-Photon Microscopy Market Size Forecast by Region
      8.2.1 North America
      8.2.2 Europe
      8.2.3 Asia Pacific
      8.2.4 Latin America
      8.2.5 Middle East & Africa (MEA)
   8.3 Market Attractiveness Analysis by Region
Chapter 9 North America Two-Photon Microscopy Analysis and Forecast
   9.1 Introduction
   9.2 North America Two-Photon Microscopy Market Size Forecast by Country
      9.2.1 U.S.
      9.2.2 Canada
   9.3 Basis Point Share (BPS) Analysis by Country
   9.4 Absolute $ Opportunity Assessment by Country
   9.5 Market Attractiveness Analysis by Country
   9.6 North America Two-Photon Microscopy Market Size Forecast By Product
      9.6.1 Microscope
      9.6.2 Software
      9.6.3 Accessories
   9.7 Basis Point Share (BPS) Analysis By Product
   9.8 Absolute $ Opportunity Assessment By Product
   9.9 Market Attractiveness Analysis By Product
   9.10 North America Two-Photon Microscopy Market Size Forecast By Type
      9.10.1 In Vivo
      9.10.2 In Vitro
   9.11 Basis Point Share (BPS) Analysis By Type
   9.12 Absolute $ Opportunity Assessment By Type
   9.13 Market Attractiveness Analysis By Type
   9.14 North America Two-Photon Microscopy Market Size Forecast By Application
      9.14.1 Material Science
      9.14.2 Nanotechnology
      9.14.3 Life Science
      9.14.4 Semiconductors
      9.14.5 Others
   9.15 Basis Point Share (BPS) Analysis By Application
   9.16 Absolute $ Opportunity Assessment By Application
   9.17 Market Attractiveness Analysis By Application
Chapter 10 Europe Two-Photon Microscopy Analysis and Forecast
   10.1 Introduction
   10.2 Europe Two-Photon Microscopy Market Size Forecast by Country
      10.2.1 Germany
      10.2.2 France
      10.2.3 Italy
      10.2.4 U.K.
      10.2.5 Spain
      10.2.6 Russia
      10.2.7 Rest of Europe
   10.3 Basis Point Share (BPS) Analysis by Country
   10.4 Absolute $ Opportunity Assessment by Country
   10.5 Market Attractiveness Analysis by Country
   10.6 Europe Two-Photon Microscopy Market Size Forecast By Product
      10.6.1 Microscope
      10.6.2 Software
      10.6.3 Accessories
   10.7 Basis Point Share (BPS) Analysis By Product
   10.8 Absolute $ Opportunity Assessment By Product
   10.9 Market Attractiveness Analysis By Product
   10.9 Europe Two-Photon Microscopy Market Size Forecast By Type
      10.9.1 In Vivo
      10.9.2 In Vitro
   10.11 Basis Point Share (BPS) Analysis By Type
   10.12 Absolute $ Opportunity Assessment By Type
   10.13 Market Attractiveness Analysis By Type
   10.14 Europe Two-Photon Microscopy Market Size Forecast By Application
      10.14.1 Material Science
      10.14.2 Nanotechnology
      10.14.3 Life Science
      10.14.4 Semiconductors
      10.14.5 Others
   10.15 Basis Point Share (BPS) Analysis By Application
   10.16 Absolute $ Opportunity Assessment By Application
   10.17 Market Attractiveness Analysis By Application
Chapter 11 Asia Pacific Two-Photon Microscopy Analysis and Forecast
   11.1 Introduction
   11.2 Asia Pacific Two-Photon Microscopy Market Size Forecast by Country
      11.2.1 China
      11.2.2 Japan
      11.2.3 South Korea
      11.2.4 India
      11.2.5 Australia
      11.2.6 South East Asia (SEA)
      11.2.7 Rest of Asia Pacific (APAC)
   11.3 Basis Point Share (BPS) Analysis by Country
   11.4 Absolute $ Opportunity Assessment by Country
   11.5 Market Attractiveness Analysis by Country
   11.6 Asia Pacific Two-Photon Microscopy Market Size Forecast By Product
      11.6.1 Microscope
      11.6.2 Software
      11.6.3 Accessories
   11.7 Basis Point Share (BPS) Analysis By Product
   11.8 Absolute $ Opportunity Assessment By Product
   11.9 Market Attractiveness Analysis By Product
   11.9 Asia Pacific Two-Photon Microscopy Market Size Forecast By Type
      11.9.1 In Vivo
      11.9.2 In Vitro
   11.11 Basis Point Share (BPS) Analysis By Type
   11.12 Absolute $ Opportunity Assessment By Type
   11.13 Market Attractiveness Analysis By Type
   11.14 Asia Pacific Two-Photon Microscopy Market Size Forecast By Application
      11.14.1 Material Science
      11.14.2 Nanotechnology
      11.14.3 Life Science
      11.14.4 Semiconductors
      11.14.5 Others
   11.15 Basis Point Share (BPS) Analysis By Application
   11.16 Absolute $ Opportunity Assessment By Application
   11.17 Market Attractiveness Analysis By Application
Chapter 12 Latin America Two-Photon Microscopy Analysis and Forecast
   12.1 Introduction
   12.2 Latin America Two-Photon Microscopy Market Size Forecast by Country
      12.2.1 Brazil
      12.2.2 Mexico
      12.2.3 Rest of Latin America (LATAM)
   12.3 Basis Point Share (BPS) Analysis by Country
   12.4 Absolute $ Opportunity Assessment by Country
   12.5 Market Attractiveness Analysis by Country
   12.6 Latin America Two-Photon Microscopy Market Size Forecast By Product
      12.6.1 Microscope
      12.6.2 Software
      12.6.3 Accessories
   12.7 Basis Point Share (BPS) Analysis By Product
   12.8 Absolute $ Opportunity Assessment By Product
   12.9 Market Attractiveness Analysis By Product
   12.9 Latin America Two-Photon Microscopy Market Size Forecast By Type
      12.9.1 In Vivo
      12.9.2 In Vitro
   12.11 Basis Point Share (BPS) Analysis By Type
   12.12 Absolute $ Opportunity Assessment By Type
   12.13 Market Attractiveness Analysis By Type
   12.14 Latin America Two-Photon Microscopy Market Size Forecast By Application
      12.14.1 Material Science
      12.14.2 Nanotechnology
      12.14.3 Life Science
      12.14.4 Semiconductors
      12.14.5 Others
   12.15 Basis Point Share (BPS) Analysis By Application
   12.16 Absolute $ Opportunity Assessment By Application
   12.17 Market Attractiveness Analysis By Application
Chapter 13 Middle East & Africa (MEA) Two-Photon Microscopy Analysis and Forecast
   13.1 Introduction
   13.2 Middle East & Africa (MEA) Two-Photon Microscopy Market Size Forecast by Country
      13.2.1 Saudi Arabia
      13.2.2 South Africa
      13.2.3 UAE
      13.2.4 Rest of Middle East & Africa (MEA)
   13.3 Basis Point Share (BPS) Analysis by Country
   13.4 Absolute $ Opportunity Assessment by Country
   13.5 Market Attractiveness Analysis by Country
   13.6 Middle East & Africa (MEA) Two-Photon Microscopy Market Size Forecast By Product
      13.6.1 Microscope
      13.6.2 Software
      13.6.3 Accessories
   13.7 Basis Point Share (BPS) Analysis By Product
   13.8 Absolute $ Opportunity Assessment By Product
   13.9 Market Attractiveness Analysis By Product
   13.9 Middle East & Africa (MEA) Two-Photon Microscopy Market Size Forecast By Type
      13.9.1 In Vivo
      13.9.2 In Vitro
   13.11 Basis Point Share (BPS) Analysis By Type
   13.12 Absolute $ Opportunity Assessment By Type
   13.13 Market Attractiveness Analysis By Type
   13.14 Middle East & Africa (MEA) Two-Photon Microscopy Market Size Forecast By Application
      13.14.1 Material Science
      13.14.2 Nanotechnology
      13.14.3 Life Science
      13.14.4 Semiconductors
      13.14.5 Others
   13.15 Basis Point Share (BPS) Analysis By Application
   13.16 Absolute $ Opportunity Assessment By Application
   13.17 Market Attractiveness Analysis By Application
Chapter 14 Competition Landscape
   14.1 Two-Photon Microscopy Market: Competitive Dashboard
   14.2 Global Two-Photon Microscopy Market: Market Share Analysis, 2019
   14.3 Company Profiles (Details – Overview, Financials, Developments, Strategy)
      14.3.1 Bruker
      14.3.2 Femtonics Ltd. 
      14.3.3 LaVision BioTec GmbH
      14.3.4 Leica Microsystems
      14.3.5 Nikon Instruments Inc.
      14.3.6 OLYMPUS CORPORATION
      14.3.7 ZEISS International

      14.3.8 Judges Scientific plc
      14.3.9 Sutter Instrument Company
Key Segments Covered
By Product
  • Microscope
  • Software
  • Accessories
By Type
  • In Vivo
  • In Vitro
By Application
  • Material Science
  • Nanotechnology
  • Life Science
  • Semiconductors
  • Others
By Region
  • North America
    • U.S.
    • Canada
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Europe
    • Germany
    • France
    • Italy
    • U.K.
    • Spain
    • Russia
    • Rest of the Europe
  • Asia Pacific
    • China
    • Japan
    • South Korea
    • India
    • Australia
    • South East Asia (SEA)
    • Rest of Asia Pacific
  • Middle East & Africa (MEA)
    • Saudi Arabia
    • South Africa
    • UAE
    • Rest of MEA

Key Market Players Profiled in the Report
  • Bruker
  • Femtonics Ltd.
  • LaVision BioTec GmbH
  • Leica Microsystems
  • Nikon Instruments Inc.
  • OLYMPUS CORPORATION
  • ZEISS International
  • Judges Scientific plc
  • Sutter Instrument Company

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FAQ Section

Some frequently asked quetions about this report!

Additional company profiles can be provided on request.

Yes, the report covers product specific information such as microscope, software, and accessories.

According to this Growth Market Reports report, the market from two-photon microscopy market shall probably to register a CAGR of 5.2% during forecast period 2020-2027, with an anticipated valuation of USD 185.1 million by the end of the 2027.

In addition to market size (in US$ Million) and Company Market Share (in % for base year 2019), other data such as impact of COVID-19 is available in the final report.

Material Science, Nanotechnology, Life Science, Semiconductors, and Others are the key applications that are driving the two-photon microscopy market.

The market is driven by factors such as increasing investments in life science research applications, rising focus on nanotechnology, growing demand for non-invasive microscopy technique, and rising emphasis on regenerative medicine.

Factors such as competitive strength and market positioning are key areas considered while selecting top companies to be profiled.

The market is expected to witness decrease of over 2.3% between 2019 and 2020 owing to the impact of COVID-19 pandemic on the two-photon microscopy market. The advances in imaging and rising demand for the two-photon microscopy is expected to grow the production two-photon microscopy market during the forecast period.

The base year considered for the global two-photon microscopy market report is 2019. The complete analysis period is 2017 to 2027, wherein, 2017 & 2018 are the historic years and the forecast is provided from 2020 to 2027.

Major Manufactures include Bruker, Leica Microsystems, Nikon Instruments Inc., OLYMPUS CORPORATION, and ZEISS International.