Superdisintegrants Market

The global superdisintegrants market size is anticipated to register a significant CAGR during the forecast period, 2021–2028. The growth of the market is attributed to the increasing pediatric & geriatric population, rising demand for generic medications, and development of new drugs in the market.

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Superdisintegrants are substances added to tablets to speed up the dissolving of the tablet into small fragments in aqueous circumstances, allowing the medicine to be released faster into the body. Superdisintegrants have been very popular in the pharmaceutical industry in recent years because they increase the solubility of active pharmaceutical ingredients in the body. The more is drug absorption, the better is bio-availability of medication. Moreover, natural compounds such as gellan gum, isapghula husk mucilage, locust bean gum, soy polysaccharide, and karaya gum are used as superdisintegrants in solid dosage forms.

On the other hand, as compared to the ordinary capsules and tablets, superdisintegrant tablets have a number of advantages such as quick action, precision dosing, palatability, cost- effective, greater patient compliance, and convenient in administration. In order to combat the COVID-19, pharmaceutical and biotech companies are partnering with governments for vaccine research and to overcome from medical supply chain obstacles all over the world. In addition, approximately 115 vaccine candidates and 155 compounds are currently being developed in medical institutes. Furthermore, regularly used drugs such as Hydroxychloroquine have seen a significant increase in demand for the treatment of the coronavirus.  

Market Trends, Drivers, Restraints, and Opportunities

• Increasing pharmaceutical consumption due to rising number of the global population and increasing prevalence of several infectious diseases is estimated to propel the demand for various superdisintegrants during the forecast period.
• Rising expenditure on healthcare infrastructure and ongoing awareness program conducted by different private & public organization are fueling the market growth.
• Less funding in the area of research and development related to superdisintegrants is expected to hamper the growth of the market.
• Unhealthy market competition by players leads to difficulty in maintaining the safety and quality of manufactured products. This is anticipated to be a major drawback of the market growth.
• Rules & regulations regarding the use of safer alternatives in synthetic substances in the pharmaceutical industry is anticipated to be an opportunity for the market to propel.

Scope of the Report

The report on the global superdisintegrants market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.

Market Segment Insights

Crospovidone segment is expected to grow at a rapid pace

Based on products, the global superdisintegrants market is segmented into ion exchange resin, crospovidone, sodium starch glycolate, croscarmellose sodium, and others. The crospovidone segment is expected to grow at a rapid pace during the forecast period owing to the ability to stabilize the amorphous condition of drugs causing to inhibition of drug recrystallization and quick solidification rate. Additionally, crospovidone is commonly used in the manufacturing of granules, tablets and capsules along with excellent disintegration and dissolving boosting effect. Another factor boosting the segment is its high hydrophilic nature, which instantly swells when it comes into contact with water, resulting in quick tablet disintegration. Modified natural products such as chitosan, chitin, xylem, cross-linked carbohydrate, and polymerized agar acrylamide are tested by researchers in order to come up with novel disintegrants.

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Tablet & capsules segment is projected to expand at a considerable CAGR

On the basis of dosages, the market is segregates as mouth-dissolving films, tablets & capsules, and others. The tablet & capsules segment is projected to expand at a considerable CAGR during the forecast period attributed to certain advantages such as the accurate dosing and cost effectiveness along with long shelf- life. Disintegrants are the most important excipients in tablet and capsule formulations as they are added to breakdown the tablet or capsule when it comes into contact with aqueous fluid. The US Food and Drug Administration (FDA) recognizes tablets and capsules as quick-dissolving dosage forms, and they are mentioned in authorized drug products with therapeutic equivalency evaluations. Hence, these factors are key drivers for boosting the segment growth.

The mouth-dissolving film segment, however, is expected to propel the market in coming years. Some of the major factors boosting the segment growth are accessibility of bigger surface area for quick disintegranting, termination in the oral cavity, and immediate action in the market.

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North America is anticipated to constitute a key market share

In terms of regions, the global superdisintegrants market is classified as Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. North America held a major revenue share of the market in 2020 and is anticipated to constitute a key market share during the forecast period. The segment growth is attributed to the better product innovation, rising demand for generic drugs, and improved production techniques of this substance. Furthermore, North America is home to some of the most important players in the superdisintegrants market.

The market of Asia Pacific, on the other hand, is projected to expand at considerable rate during the forecast period. Some of the key factors driving the regional market growth include increasing demand for outsourcing of excipients, manufacturing of new superdisintegrants, and adopting of novel technology.

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Segments

Segments Covered in the Report

The global superdisintegrants market has been segmented on the basis of

Products

• Ion Exchange Resin
• Crospovidone
• Sodium Starch Glycolate
• Croscarmellose Sodium
• Others

Dosages

• Mouth-dissolving Films
• Tablets & Capsules
• Others

Regions

• Asia Pacific
• North America
• Latin America
• Europe
• Middle East & Africa

Key Players

• Roquette Frères S.A.
• Ashland Global Holdings Inc.
• DFE Pharma
• FMC Corp.
• Huber Corp.
• BASF SE.
• Nippon Soda Co. Ltd.
• The Dow Chemical Co.

Competitive Landscape

Some of the key players competing in the global superdisintegrants market are Roquette Frères S.A.; Ashland Global Holdings Inc.; DFE Pharma; FMC Corp.; Huber Corp.; BASF SE.; Nippon Soda Co. Ltd.; and The Dow Chemical Co. These industry leaders are implementing marketing strategies such as mergers, acquisitions, and geographical expansion, merger & acquisition, collaborations, and new product launches to increase the market share during the forecast period.

Formulationbio announced the launch of disintegrant excipients for medical preparation in March 2021. DFE Pharma's supply chain of pharmaceutical excipients was effectively streamlined in July 2018. Furthermore, it has made significant investments in factory capabilities to meet the rising demand for high-quality excipients such as microcrystalline cellulose, and pharmaceutical grade lactose. In October, 2019, a new pharmaceutical R&D center and customer technical service facility has been started by Roquette Frères S.A. in Biopolis, Singapore for the development of new medications & application of products and preclinical research. Additionally, in March 2016, Roquette had been awarded the EXCiPACT certification for good industrial practices, consisting testing, manufacturing, and packaging of variety of excipients.