Segments - by Type (Microbial Bioreactors/Fermenters, Cell Culture Bioreactors, Single-Use/Disposable Bioreactors, Bioreactors for Special Applications), by Capacity (Less than 10L, 11L-20 L, 21L-30L, More than 30L), by Application (Antibodies, Viral Vectors, Cell Therapies, Others), by End-user (Pharmaceutical and Biopharmaceutical Companies, Contract Development and Manufacturing Organizations (CDMOs))
The Global Stirred Tank Bioreactor Market was estimated at USD 1,962.5 Million in 2023 and is anticipated to reach USD 4,148.0 Million by 2032, expanding at a CAGR of 8.9% during the forecast period.
A Stirred Tank Bioreactor (STR), also called a mixing tank bioreactor, is a closed vessel designed to provide a controlled environment for cultivating biological materials such as cells, microorganisms, or tissues. STR offers a medium that provides nutrients for cells to grow in and delivers sufficient mixing and aeration to the culture to encourage growth.
The GDP growth rate of a country, the overall economic growth, and the stability of a country significantly impact the market across the globe. High GDP growth rates lead to increased spending and investments in product development. Emerging economies such as Russia, India, China, the UAE, and other countries in Southeast Asia and Latin America are key destinations for various industries. According to the International Monetary Fund, the economic growth of emerging countries is growing by about 6% annually, whereas countries with an already well-established economy report growth rates below 3%. Countries with high GDP growth rates tend to have high expenditures. Thus, rising GDPs of emerging countries play a crucial role in fuelling the market.
Research & development (R&D) plays a significant role in determining the growth and future advancements of a country or region. According to the National Science Foundation, the total global R&D spending in the biotechnology industry is registered at around USD 88.6 billion in 2021. R&D spending in the biotechnology industry doubled in the last five years, from 2018 to 2022. North America accounts for 59% of the global R&D spending, followed by Europe at 34%, and the Asia Pacific at 7% in 2022. R&D plays an enormous role from discovery to final approval and marketing, where regulatory bodies act as checkpoints. R&D has a major impact on the overall market.
Bioreactor systems are revolutionizing various industries by providing a controlled environment for cultivating cells, and microorganisms. They act as miniature ecosystems, mimicking the ideal conditions for specific biological processes. In the bio-pharmaceutical industry, bioreactors are used in the large-scale production of vaccines, insulin, antibiotics, and other life-saving drugs. Bioreactors enable the controlled growth of cells producing vital medications. In biofuels and biomaterials industries, these systems are used to cultivate microorganisms that produce biofuels as a sustainable alternative to fossil fuels. They are also used to create bioplastics and other biomaterials that have reduced environmental impact.
In tissue engineering applications, bioreactors hold potential in regenerative medicine by culturing specific cells. In food production, bioreactor systems are used for the fermentation of food products such as yogurt and beer. They also offer possibilities for cultivating alternative protein sources such as cultured meat. Thus, the growing adoption of bioreactor systems is projected to drive the market in the coming years.
Contract manufacturing organizations (CMOs) are specialized companies offering a range of services to pharmaceutical and biotechnology companies, including the development, manufacturing, and packaging of drugs and therapies. CMOs offer a cost-effective solution, as developing and maintaining in-house biomanufacturing capabilities are expensive. STRs help CMOs to scale production processes, from initial research to large-scale manufacturing, efficiently.
CMOs are expanding their global presence, particularly in regions with low manufacturing costs. This is expected to lead to the establishment of new CMO facilities, thus driving the demand for STRs. Thus, the expansion of CMOs is projected to drive the stirred tank bioreactors market in the coming years.
STRs are complex pieces of machinery with moving parts and sensitive components requiring regular maintenance and occasional repairs to ensure optimal performance. STRs require specialized facilities with controlled temperature, humidity, and air quality, which in turn, increases the operational costs. The ongoing costs accumulate, as bioprocessing necessitates a constant supply of consumables such as culture media, filters, and sterilization agents. Additionally, the cost of employing qualified personnel is significant, as operating and maintaining STRs requires skilled personnel with a deep understanding of bioprocessing principles and aseptic techniques.
Biopharmaceutical companies constantly seek ways to reduce production costs. High operational expenses associated with STRs prompt to exploration of alternative technologies. The high costs associated with STRs limit their adoption in developing countries thus, hindering the market.
The healthcare industry is shifting toward personalized medicine that involves tailoring treatments to individual patients. This necessitates research & development (R&D) efforts to develop novel therapies such as gene editing and cell therapies, often relying on stirred tank bioreactors for efficient cell cultivation.
R&D efforts are directed toward developing new drugs and therapies, due to the growing emphasis on addressing unmet medical needs in areas such as cancer, neurodegenerative diseases, and rare genetic disorders. R&D activities are crucial for exploring advancements and translating them into tangible applications in areas such as gene editing and synthetic biology. Furthermore, the demand for STRs from research institutions, biotechnology companies, and academic labs is expected to rise significantly in the coming years. Thus, the growing research & development is projected to create new growth opportunities during the forecast period.
The report on the global stirred tank bioreactor market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes |
Details |
Report Title |
Stirred Tank Bioreactor Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast |
Base Year |
2023 |
Historic Data |
2017–2022 |
Forecast Period |
2024–2032 |
Segmentation |
By Type (Microbial Bioreactors/Fermenters, Cell Culture Bioreactors, Single-Use/Disposable Bioreactors, Bioreactors for Special Applications), By Capacity (Less than 10L, 11L-20 L, 21L-30L, more than 30L), By Application (Antibodies, Viral Vectors, Cell Therapies, Others), By End-user (Pharmaceutical and Biopharmaceutical Companies, Contract Development and Manufacturing Organizations (CDMOs)) |
Regional Scope |
Regions (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) |
Report Coverage |
Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, and Trends, and Revenue Forecast |
Key Players Covered |
ABEC; Bailun Biotechnology Co.,Ltd; BRS Biotech OÜ; Danaher Corporation (Cytiva); Eppendorf SE; Esco VacciXcell; MDX Biotechnik International GmbH; Merck KGaA; Sartorius AG; Thermo Fisher Scientific Inc; and Other |
On the based-on Type, the stirred tank bioreactor market is segmented into microbial bioreactors/fermenters, cell culture bioreactors, single-use/disposable bioreactors, and bioreactors for special applications.
The microbial bioreactors/fermenters segment is expected to hold a significant share of 28.8% during the forecast period, as it is a key method for producing enzymes used in various industries, such as food processing and biocatalysis.
Based on capacity, the stirred tank bioreactor market is segmented into less than 10L, 11L-20 L, 21L-30L, and more than 30L.
The less than 10L segment register a substantial share of the market in the coming years, as it is widely used in universities, research institutions, and biotechnology companies. An increase in investments in life sciences research fuels the demand for benchtop models.
On the basis of application, the stirred tank bioreactor market is segregated into antibodies, viral vectors, cell therapies, and others.
The antibodies segment is expected to hold a significant share of the market during the forecast period, as STRs are widely used for antibody-based therapeutics. Monoclonal antibodies are used to treat various diseases such as cancer, autoimmune disorders, and infectious diseases.
In terms of end-user, the stirred tank bioreactor market is fragmented into pharmaceutical and biopharmaceutical companies and contract development and manufacturing organizations (CDMOs).
The pharmaceutical and biopharmaceutical companies segment is expected to grow at a substantial CAGR during the forecast period, due to the rising demand of STRs in pharmaceutical and biopharmaceutical companies. Pharmaceutical companies are constantly investing in the R&D of novel biopharmaceuticals, leading to a need for STRs for pilot-scale production and clinical trials.
Based on regions, the market is separated into namely, North America, Europe, Asia Pacific, Latin America, and Middle East & Africa.
The market in North America is estimated to expand at a CAGR of 8.8% during the forecast period, owing to the presence of a well-established biopharmaceutical industry, strong academic research institutions, and government support for biotechnology. North America has a robust regulatory framework ensuring the quality and safety of biopharmaceuticals produced using STRs.
Europe accounted for a 30.7% share of the market in 2023, due to rising demand for biopharmaceuticals, including vaccines, monoclonal antibodies, and gene therapies. Increased collaboration between academic institutions, biopharmaceutical companies, and STR manufacturers also accelerates innovation and optimizes bioprocessing efficiency. The growth of Contract Development and Manufacturing Organizations (CDMOs) in Europe increases the need for advanced STR infrastructure.
In-depth Analysis of the Global Stirred Tank Bioreactor Market
Historical, Current, and Projected Market Size in terms of Value
Potential & Niche Segments and Regions Exhibiting Promising Growth Covered
Industry Drivers, Restraints, and Opportunities Covered in the Study
Recent Industry Trends and Developments
Competitive Landscape & Strategies of Key Players
Neutral Perspective on Global Stirred Tank Bioreactor Market Performance
Manufacturers operating in the global Stirred Tank Bioreactor market are ABEC; Bailun Biotechnology Co., Ltd; BRS Biotech OÜ; Danaher Corporation (Cytiva); Eppendorf SE; Esco VacciXcell; MDX Biotechnik International GmbH; Merck KGaA; Sartorius AG; Thermo Fisher Scientific Inc; and Other.
Market Players are pursuing key strategies such as collaborations, mergers & acquisitions, and geographic expansion where a potential opportunity arises for the global Stirred Tank Bioreactor market.
Additional company profiles can be provided on request. For a discussion related to the above findings, click Speak to Analyst
Factors such as competitive strength and market positioning are key areas considered while selecting top companies to be profiled.
Increasing Adoption of Bioreactor Systems in Industrial Application, Expansion of Contract Manufacturing Organization (CMOs)are the factors expected to drive the market growth during the forecast period.
According to this Growth Market Reports report, the Global Stirred Tank Bioreactor Market is likely to register a CAGR of 8.9% during the forecast period 2024-2032, with a projected valuation of USD 4,148.0 million by the end of 2032.
Pharmaceutical and Biopharmaceutical Companies are the major end user of the global stirred tank bioreactor market.
Factors such as the rising GDP of emerging economies, governmental spending, and R&D activities are analyzed in the final report.
Major manufacturers include ABEC; Bailun Biotechnology Co., Ltd; BRS Biotech OÜ; Danaher Corporation (Cytiva); Eppendorf SE; Esco VacciXcell; MDX Biotechnik International GmbH; Merck KGaA; Sartorius AG; Thermo Fisher Scientific Inc; and Other.
The outbreak of Coronavirus disease in 2019 (COVID-19) hampered the global economy, created global interdependence, and challenged the governments of various nations. Numerous industries across the globe had significantly affected, due to the COVID-19 pandemic. The pandemic caused massive disruptions in supply chains, affecting the production and distribution of products.
In addition to market size (in US$ Million), Company Market Share (in % for the base year 2023), macroeconomic factors, and Market Dynamics.
The base year considered for the global stirred tank bioreactor market report is 2023. The complete analysis period is 2017 to 2032, wherein, 2017 to 2022 are the historic years, and the forecast is provided from 2023 to 2031.