The global spinal fusion bone graft substitute market size is anticipated to expand at a substantial CAGR during the forecast period, 2021–2028. The growth of the market is attributed to the rising preference for minimal invasive surgeries, increasing old-age population, and growing number of diseases such as kyphosis, scoliosis, and degenerative disc disease (DDD).

Bone grafting is a technique that includes the surgical replacement of lost bone. Various types of bone grafts including allograft, autologous bone graft, and artificial bone graft are utilized for grafting methods. The fusion of a bone can be referred to as a method of envelopment and inter-digitation of the bone tissue from a donor by the new bone to the recipient. The most successful type of bone graft is natural bone graft and is anticipated to be the high standard for the replacement of bones. Bone grafts have an application in tumor filling, to fill the space occurred due to cysts and speedy healing of fractures.
Spinal fusion is a technique in which issues related to spinal bone are fixed by the use of a spinal bone graft. A research study of Ethicon Endo-Surgery Inc. states that the demand for minimally invasive procedures has increased tremendously by replacing the invasive surgery technique. The operation for scoliosis is a spinal fusion. Scoliosis surgeons improve curves with the help of tools and technology available today. However, spinal fusion is a major surgery performed under general anesthesia. It is recommended when a scoliosis curve measures over 50 degrees. Thus, scoliosis bracing, Mehta casting, bodyweight exercise, and traditional physical therapy treatment are suggested for those who do not need to have surgery on their spine.
The COVID-19 pandemic has negatively impacted the market. As the COVID-19 outbreak caused several restrictions and nation-wide lockdowns, it led to cancellation of many surgeries during the pandemic. Government policies to defer non-emergency surgeries and healthcare activities to reduce the burden of the healthcare sector is also a key factor for decline in the market growth during the pandemic widespread.
Market Trends, Drivers, Restraints, and Opportunities
- Presence of technologically advanced substitutes such as Grafton, nanOss loaded advanced bone graft substitute, and VITOSS is driving the market growth.
- Rising number of the surgeons and their awareness about the advantages of the allograft and autograft are propelling the market expansion.
- Increasing medical awareness and changing mindsets of people are key factors boosting the market growth.
- Various advantages of the non-invasive surgeries haves reduced number of post-surgery complications, relatively lesser number of hospital stays, increased patient satisfaction, and lower mortality rates. This is driving the market growth.
- Advancements in the technologies and high awareness among the population are likely to offer huge opportunities for the market development during the forecast period.
Scope of the Report
The report on the global spinal fusion bone graft substitute market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes
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Details
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Report Title
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Spinal Fusion Bone Graft Substitute Market - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast
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Base Year
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2020
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Historic Data
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2018–2019
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Forecast Period
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2021–2028
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Segmentation
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Processes (Demineralized Bone Matrix, Bone Morphogenetic Proteins, Synthetic Bone Graft Extenders, Stem Cell Therapy, and Visco Supplements)
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Regional Scope
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Asia Pacific, North America, Latin America, Europe, and Middle East & Africa
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Report Coverage
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Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, and Trends, and Revenue Forecast
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Key Players Covered in the Report
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DePuy Synthes; Stryker; MTF; AlloSource; Baxter; Wright Medical; Integra LifeSciences; Bacterin International; LifeNet Health; RTI Surgical; Alphatec Spine; Arthrex; Berkeley Advanced Biomaterials; Biomet; Osteogenics; and Etex Corporation.
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Market Segment Insights
Demineralized bone matrix segment is expected to grow at a rapid pace
Based on processes, the global spinal fusion bone graft substitute market is divided into synthetic bone graft extenders, demineralized bone matrix (DBM), bone morphogenetic proteins, stem cell therapy, and visco supplements. The demineralized bone matrix segment is expected to grow at a rapid pace during the projected period owing to the good results, osteoinductivity associated with it, and high prices.
The stem cell therapy segment, however, is anticipated to grow at significant pace in the coming years due to its high demand, great potential of regeneration that heals the bone quickly, and high effectiveness in terms of replacement of any tissue without the need of donor.

North America is anticipated to constitute a key market share
In terms of regions, the market is classified as Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. North America is anticipated to constitute a key market share in the coming years owing to the highly advanced healthcare facilities, presences of highly skilled professionals, and large scale funding from key market players in the region. Moreover, favorable government policies along with reimbursement facilities is driving the market in the region.
Meanwhile, the Asia Pacific market is anticipated to account for a major market share during the projected period due to the presence of high old age population, developing healthcare infrastructure, and rising disposable income of a large number of the regional population. Furthermore, presence of large untapped population and raised spending capacity of the people in the region are propelling the market expansion in the region.

Segments
The global spinal fusion bone graft substitute market has been segmented on the basis of
Processes
- Demineralized Bone Matrix
- Bone Morphogenetic Proteins
- Synthetic Bone Graft Extenders
- Stem Cell Therapy
- Visco Supplements
Regions
- Asia Pacific
- North America
- Latin America
- Europe
- Middle East & Africa
Key Players
- DePuy Synthes
- Stryker
- Integra LifeSciences
- AlloSource
- Baxter
- Wright Medical
- Alphatec Spine
- Bacterin International
- LifeNet Health
- Arthrex
- Berkeley Advanced Biomaterials
- Biomet
- RTI Surgical
- Osteogenics
- Etex Corporation
Competitive Landscape
The key players competing in the global spinal fusion bone graft substitute market are DePuy Synthes; Stryker; MTF; Integra LifeSciences; AlloSource; Baxter; Wright Medical; Alphatec Spine; Bacterin International; LifeNet Health; Arthrex; Berkeley Advanced Biomaterials; Biomet; RTI Surgical; Osteogenics; and Etex Corporation.
