Proteomics Market Size, Share, Analysis & Forecast [2031]

Report Description

Proteomics Market Outlook 2031

The global proteomics market size was USD 25.67 Billion in 2022 and is likely to reach USD 70.57 Billion by 2031, expanding at a CAGR of 13.5% during 2023–2031. The market growth is attributed to the increasing prevalence of chronic diseases and the high demand for nano proteomics.

Increasing prominence of nanoproteomics is expected to drive the proteomics market in the coming years. The rise of micro and nanoflow in proteomics has led to the development of nanoproteomics. Nanoscale samples are generated by innovative techniques such as laser capture micro-dissection (LCM), fluorescence-activated cell sorting (FACs), and miniaturized lab-on-chip microfluidic devices.
 

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Increasing prevalence of chronic diseases such as cancer, respiratory disease, cardiovascular diseases, and others is expected to fuel the market. Proteomic-based technologies enable the identification of protein expression patterns and potential biomarkers that are used to access tumor classification, tumor prognosis, and prediction, and identify potential responders for specific therapies.

• According to the American Cancer Society, in the US, it is estimated that around 1.9 million new cancer cases were diagnosed and 609,360 cancer deaths occurred in 2022.

The market report finds that the COVID-19 pandemic hampered the market, due to the increasing demand for proteomics services. Mass spectrometry (MS) based proteomics is recognized as an ideal technique for detecting infection-related changes in proteins.

MS techniques are widely used to explore several aspects of viral and host infection during the pandemic. Several companies and research institutes were temporarily shut down during the pandemic. Strict regulations were imposed by the government during the pandemic, which hampered the proteomics market.

Impact of Artificial Intelligence in the Proteomics Market

Artificial intelligence (AI) technologies are expected to boost the market during the forecast period. AI is used in proteomics to accelerate research through comprehensive peptide and protein identification and qualification. AI-based search algorithms offer an opportunity to rethink the analysis of tandem mass spectra, enhancing coverage and efficacy in proteomic research.

Machine learning (ML) techniques are applied in two ways, such as directly on the mass spectral peaks or on the proteins identified by sequence database searching.

• In January 2023, Quantum-Si Incorporated partnered with Biovista to offer customers with greater proteomic insights beyond their protein sequence output. Biovista leverages AI in numerous formats to examine massive data repositories and visualize non-obvious networks and associations between diseases, proteins, and drug mechanisms of action. The partnership improves Quantium-Si Incorporated’s offering by making proteomic-to-drug workflows efficient for researchers.

Proteomics Market Dynamics

Major Drivers

Increasing demand for personalized medicine is expected to boost the proteomics market during the forecast period. Proteomics plays an important role in personalized medicine, as it provides information about physiological differences between biological samples that are based on protein abundance levels.

The adoption of precision medicine is increasing, owing to improved healthcare efficiency and better patient outcomes, which is expected to fuel the proteomics market.

Existing Restraints

High cost of proteomics instruments is expected to hamper the proteomics market. The use of proteomics research expands from the discovery of vaccines, novel drugs, and clinical targets to the classification of protein-based products and toxicology.

It involves the use of various types of instruments and platforms, and laboratory documentation systems, databases, and software, which contribute to the high cost of protein analytics. This, in turn, is expected to hamper the proteomics market.

Emerging Opportunities

Technological advancements in the market are expected to create lucrative opportunities for the market players. Technological advancements such as next-generation sequencing, protein microarrays, and mass spectrometry improve the speed, sensitivity, and accuracy of proteomics analysis.

Several companies are increasing their investments to develop technologies in proteomics, which is expected to boost the market during the forecast period.

• In June 2021, Bruker launched timsTOF instruments, as they advance and enable new applications and methods in unbiased proteomics, deep multiomic biomarker discovery, epi proteomics/PTM characterization, and others, for instance, in cancer liquid biopsy research. Bruker is making major progress in unbiased single-cell proteomics, phosphoproteomics, and plasma proteomics, leveraging the speed, sensitivity, and dynamic range of large-scale CCS-enabled 4DpProteomics and 4D-epiproteomics.

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Scope of Proteomics Market Report

The market report includes an assessment of the market trends, market segments, and regional markets. Overview and dynamics have also been included in the report.

Proteomics Market Segment Insights

Reagent Segment Analysis

Based on reagent, the proteomics market is divided into spectroscopy, immunoassay, electrophoresis, chromatography, protein fractionation, and others. The immunoassay segment is expected to expand at a significant pace during the projection period, owing to the increasing need for reliable, specific, and fast detection of diseases and the availability of a wide range of reagents.

The segment growth is further attributed to the increasing number of applications of immunoassay, including drug discovery & development, clinical diagnostics, and others; high usage of proteomics in drug discovery; and high demand for personalized medicine.

High usage of reagents & consumables, chemicals, kits, and strips for the examination of several biological samples in research labs, academic institutions, and others boosts the segment.

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Instrumentation Technology Segment Analysis

In terms of instrumentation technology, the global market is segregated into spectroscopy, electrophoresis, chromatography, protein microarrays, protein fractionation, and others. The spectroscopy segment is further segmented into NMR spectroscopy, mass spectroscopy, and CD spectroscopy.

The electrophoresis segment is further divided into capillary and gel. The chromatography segment is further segregated into ion chromatography, HPLC, affinity, and superficial. The protein microarrays segment is further bifurcated into microarray instruments and biochips.

The protein microarrays segment is projected to expand at a considerable CAGR during the forecast period. Protein microarrays determine the functions of proteins and monitor their interactions. The structure of the arrays allows for numerous proteins, which are tracked in parallel.

It has the ability to simultaneously measure multiple proteins in a single experiment as compared with traditional methods, thereby increasing the adoption of protein microarrays in the market. The segment growth is further attributed to the growing need for high-throughout technologies and high demand for personalized medicines.

The spectroscopy segment is anticipated to account for a major market share in the coming years, due to the increasing demand for mass spectroscopy. In proteomics, mass spectroscopy gives information on the protein identity, its chemical modifications, and its structure.

Yhe segment growth is further attributed to the high demand for spectroscopy techniques in research and drug discovery and the increasing number of laboratories for proteomics.

Software & Services Segment Analysis

On the basis of software & services, the proteomics market is segmented into bioinformatics and core proteomics services. The core proteomics services segment is expected to register robust growth during the forecast period, as it provides global proteomic profiling of samples.

The proteomics core provides a complete characterization of antibodies, including intact deglycosylated mass, intact exact mass, deglycosylated subunit analysis, subunit analysis, and glycopeptide analysis with glycoform maps and peptide sequencing.

Application Segment Analysis

In terms of application, the global market is segregated into clinical diagnostics, drug discovery & development, and others. The clinical diagnostics segment is anticipated to hold a key share of the market in the coming years, due to the rising need for accurate and early disease diagnosis and the high demand for personalized medicine.

The segment growth is further attributed to the increasing adoption of protein analysis among clinical researchers to identify disease biomarkers for the early detection of diseases and identifying individual risk factors.

The drug discovery segment is anticipated to account for a major market share in the coming years, due to the development of structure-based drug design and high emphasis on making personalized drugs.

Proteomics technologies provide a way to get a head start on a drug discovery program, saving pharmaceutical corporations significant amounts of capital and ultimately benefiting patients as well as the healthcare systems.

• In February 2023, Biognosys introduced that its TrueTarget platform is now powered by an improved version of its proprietary Limited Proteolysis Mass Spectrometry (LiP-MS) technology. The new and improved LiP-MS workflow searches the proteome broadly and characterizes peptides accurately to provide high likelihood of success and level of confidence for the identification of drug targets.

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End-user Segment Analysis

Based on end-user, the global proteomics market is segmented into clinical laboratories, hospitals, academic research laboratories, and others. The hospitals segment is projected to hold a large market share in the coming years, as it allows healthcare providers to measure and track patient health risks historically and in real-time.

Several proteomics techniques are used to detect biomarkers in cancer, such as cancer immunomics, nano-proteomics, aptamer-based molecular probes, and antibody microarrays. This, in turn, is expected to increase the demand for proteomics in hospitals.

Regional Analysis

In terms of region, the global proteomics market is classified as Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. North America is expected to dominate the market during the projection period, due to the increasing demand for high-quality research tools for data reproducibility and rising investments in the development of structure-based drug design.

The regional market growth is further attributed to the rapid growth in omics research, development of tailored treatments, and increasing partnerships and collaborations among several key players.

• In March 2022, Thermo Fisher Scientific announced the continuation of its collaboration with Symphogen to provide biopharmaceutical discovery as well as offer development laboratories with innovative tools and streamlined workflows for the efficient characterization of complex therapeutic proteins.

The market in Asia Pacific is anticipated to expand at a rapid pace in the coming years, owing to the increasing prevalence of target diseases on account of the aging population and favorable government regulations.

The regional market growth is further attributed to the increasing funding for the research & development of proteomics studies and high-adoption of proteomics in emerging countries such as China and India.

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