Protein Sequencing Market Size, Share & Trends Growth [2031]

Report Description

Protein Sequencing Market Outlook

The Global Protein Sequencing Market was estimated at USD 1,143.0 Mn in 2022 and is anticipated to reach USD ~1,656.4 Mn by 2031, expanding at a CAGR of 4.4% during the forecast period. 

Protein sequencing: Protein sequencing refers to the process of determining the amino acid sequence of all or part of a protein or peptide. It serves to identify the protein or characterize its post-translational modifications. Typically, partial sequencing of a protein provides sufficient information (one or more sequence tags) to identify it with reference to databases of protein sequences derived from the conceptual translation of genes.

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Macro-economic Factors

Government Policies

Governments, including ministries of health and other related ministries and agencies, play a crucial role in the overall development of a strong healthcare system in a region. Stringent policies of government determine the growth and decline of a specific market in a particular country. These government policies differ from country to country or region to region.

In North America, the protein sequencing market is regulated by several government bodies, such as the US Food and Drug Administration (FDA) and Health Canada. They have enforced strict regulations to ensure the high quality and safety of protein sequencing technologies. Regulations cover various aspects, such as device functionality, effectiveness, labeling, production process, and post-market surveillance.

Protein Sequencing Market Dynamics

Market Driver- Rising Prevalence of Chronic Diseases Requiring Protein Sequencing

The global protein sequencing market is registering significant growth, due to the rising prevalence of chronic diseases, such as cancer, Alzheimer's, and Parkinson's. Protein sequencing is a crucial technique that is used to determine the amino acid sequence of proteins, which is essential for understanding their structure, function, and interaction with other molecules.

Increasing incidence of chronic diseases has led to a surge in demand for protein sequencing, as it helps in the identification of disease-causing mutations, development of targeted therapies, and personalized medicine.

Cancer is a leading cause of death worldwide, with an estimated 18.1 million new cancer cases and 9.6 million cancer-related deaths in 2020, according to the World Health Organization (WHO). Protein sequencing is used to identify genetic mutations that drive cancer growth and progression, as well as to develop targeted therapies that selectively kill cancer cells while sparing healthy cells.

Market Restraint- High Cost of Protein Sequencing Equipment and Procedures

High cost of protein sequencing equipment and procedures is restraining the protein sequencing market. The cost of mass spectrometry instruments, which are the primary tools used for protein sequencing, ranges from several hundred thousand to millions of dollars. This high cost makes it difficult for small research institutions and laboratories to invest in these technologies, limiting their access to the latest protein sequencing techniques.

Several companies are developing technologies that offer low costs and high throughput to address the high cost of protein sequencing equipment and procedures. For example, Thermo Fisher Scientific has developed its Orbitrap Fusion Lumos mass spectrometer, which offers higher sensitivity and resolution than traditional mass spectrometry instruments at a lower cost.

Similarly, Bruker Corporation has developed timsTOF Pro 96 mass spectrometer, which offers higher sensitivity and resolution than traditional mass spectrometry instruments at a lower cost per sample.

Market Opportunity- Expanding Pharmaceutical and Biotechnology Industry Globally

The expansion of the pharmaceutical and biotechnology industry globally is driving the market by several factors. Protein sequencing is a critical step in the development of drugs, diagnostics, and therapeutics, as it provides detailed information about the structure and function of proteins, which are essential for understanding their role in various biological processes.

One of the major factors driving the expansion of protein sequencing in the pharmaceutical and biotechnology industry is the increasing demand for personalized medicine. Protein sequencing allows for the identification of genetic variations that affect protein function, which is crucial for developing targeted therapies that are tailored to an individual's genetic makeup.

For instance, Thermo Fisher Scientific has been investing in R&D activities to develop mass spectrometry-based solutions for proteomics research, such as its Orbitrap Fusion Lumos mass spectrometer, which offers high sensitivity and resolution for protein identification and quantification. Similarly, Bruker Corporation has been developing technologies, such as its timsTOF Pro 96 mass spectrometer, which offers high sensitivity and resolution for protein sequencing applications.

Scope of Protein Sequencing Market Report            

The report on the global Protein Sequencing market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.

Protein Sequencing Market Segmental Outlook

Based on Products and Services, the market is segmented into instruments, reagents & consumables, and software & services. The instruments segment is expected to hold a considerable share of the market during the forecast, as instruments are widely used to characterize post-translational modifications.

Protein post-translational modifications (PTMs) increase the functional diversity of the proteome by the covalent addition of functional groups or proteins, proteolytic cleavage of regulatory subunits, or degradation of entire proteins.

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On the basis of Technology, the market is fragmented into sequencing-by-degradation, sequencing-by-transit, and sequencing-by-affinity. The sequencing-by-degradation held the significant share of the market in 2022. It is a well-known method for obtaining amino acid (AA) sequences from a peptide by sequential reactions that release the N-terminal AAs from the peptide as a phenylthiohydantoin (PTH) derivative.

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In terms of Application, the market is classified as biomarker discovery, protein engineering studies, biotherapeutics, and others. The biomarker discovery segment is anticipated to expand at a significant CAGR during the forecast period, as proteomics biomarker discovery is crucial in a variety of diseases, such as cancer, cardiovascular diseases, acquired immune deficiency syndrome (AIDS), renal diseases, and diabetes.

On the basis of End-user, the market is fragmented into academic institutes & research centers, pharmaceutical & biotechnology companies, contract research organizations, and others. The pharmaceutical & biotechnology companies held the significant share of the market in 2022, as these companies widely use protein sequencing in various ways, including drug discovery, target identification, and the development of personalized medicine.

Regional Outlook

Based on regions, the market is fragmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America accounted for a significant share of the market in 2022. The protein sequencing market in North America is influenced by several factors. The growth of the market in the region is attributed to the presence of well-established academic institutions and research centers in the region and increasing funding in R&D.

For instance, according to the National Center for Science and Engineering Statistics (NCSES), total research & experimental development (R&D)​ performed in the US totaled USD 717.0 billion in 2020.

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   Key Benefits for Industry Participants & Stakeholders

• In-depth Analysis of the Global Protein Sequencing Market

• Historical, Current, and Projected Market Size in Terms of Value

• Potential & Niche Segments and Regions Exhibiting Promising Growth Covered

• Industry Drivers, Restraints, and Opportunities Covered in the Study

• Recent Industry Trends and Developments

• Competitive Landscape & Strategies of Key Players