Segments - Ovarian Cancer Drugs Market by Therapeutic Class (PARP Inhibitors, Angiogenesis Inhibitors, and PD-L1 Inhibitors), and Regions (Asia Pacific, North America, Latin America, Europe, and Middle East & Africa) - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast 2023 – 2031
The Global Ovarian Cancer Drugs Market size was valued at USD 3.37 Billion in 2022 and is likely reach to USD 5.99 Billion by 2031, expanding at a CAGR of 6.6% during the forecast period, 2023–2031. The growth of the market is attributed to the rising prevalence of ovarian cancer due to an aging population and bad lifestyles.
The ovaries are two reproductive glands in females that generate ova, or eggs. They also make estrogen and progesterone, which are feminine hormones. When abnormal cells in the ovary begin to proliferate out of control and form a tumor, this is referred to as ovarian cancer. The tumor might spread to other regions of the body if it is not treated.
Metastatic ovarian cancer is the term for this type of malignancy. Warning indications of ovarian cancer are common, although the early symptoms are frequently vague and easy to dismiss. Ovarian cancer is identified at an early stage in 20% of cases. Ovarian cancer's specific cause is undetermined.
A family history of ovarian cancer, genetic abnormalities in ovarian cancer genes such as BRCA1 or BRCA2, a personal history of breast, uterine, or colon cancer, obesity, the use of certain fertility medications or hormone treatments, no history of pregnancy, and endometriosis can all raise patient’s risk.
Three types of cells make up the ovaries. Each cell has the potential to become a distinct form of tumor. Epithelial cancers develop in the outer layer of tissue of the ovaries. Epithelial tumors make up around 90% of ovarian malignancies. Stromal cancers develop in the cells that produce hormones.
Stromal tumors make up 7% of all ovarian malignancies. Germ cell cancers form in the cells that produce eggs. Germ cell cancers are extremely uncommon.
When doctor identifies ovarian cancer early on, it is significantly simpler to treat. It is, however, difficult to identify. The following tests may also be performed by the doctor. Transvaginal ultrasound (TVUS), CT scans of the abdomen and pelvis, blood tests to determine cancer antigen 125 (CA-125) levels, biopsies, and laparoscopies are all tests’ options for diagnosis.
It is crucial to remember that, while all of these tests can assist doctor in making a diagnosis, only a biopsy can confirm whether or not patients have ovarian cancer. The therapy is determined on the extent of the cancer's spread. Depending on your circumstances, a team of specialists will devise a treatment plan.
Chemotherapy, surgery to stage the disease and remove the tumor, targeted therapy, and hormone therapy are all likely to be part of the treatment plan. There are no established methods for completely removing your risk of ovarian cancer. There are, however, actions you may do to reduce your risk.
Taking oral birth control pills, nursing, pregnancy, and surgical operations on your reproductive organs have all been proven to reduce your chance of getting ovarian cancer (like a tubal ligation or hysterectomy). The most prevalent form of ovarian cancer is epithelial ovarian cancer.
Survival rates may vary depending on the kind of ovarian cancer, how far the disease has progressed, and how far therapies have progressed. Scientists are actively working on more refined and reliable methods of early detection of ovarian cancer. Treatment progresses, and with it, the prognosis for ovarian cancer improves.
Several Phase II and III clinical studies examining checkpoint inhibitors in combo regimens are under underway. Unmet needs in the ovarian cancer medication market offer a great potential to develop ground-breaking first-in-class treatments. The introduction of non-platinum-based PARP inhibitors and VEGF inhibitors in second and third-line ovarian cancer treatment is radically altering the therapeutic paradigm.
Companies are increasingly concentrating their efforts on the development of targeted medicines as innovative ovarian cancer treatment regimens. With many first-in-class breakthroughs, the future treatment market is likely to gain an assortment of novel targets and therapy types, extending the breadth of possible advantages for patients.
The report on the global ovarian cancer drugs market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes |
Details |
Report Title |
Ovarian Cancer Drugs Market - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast |
Base Year |
2022 |
Historic Data |
2016–2021 |
Forecast Period |
2023–2031 |
Segmentation |
Therapeutic Class (PARP Inhibitors, Angiogenesis Inhibitors, and PD-L1 Inhibitors) |
Regional Scope |
Asia Pacific, North America, Latin America, Europe, and Middle East & Africa |
Report Coverage |
Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, and Trends, and Revenue Forecast |
Key Players Covered in the Report |
AstraZeneca; Roche; Tesaro; Pfizer; AbbVie; ImmunoGen; Johnson & Johnson; Boehringer Ingelheim; Oasmia Pharmaceuticals; and Clovis Oncology |
Based on therapeutic class, the ovarian cancer drugs market is segmented into PARP inhibitors, angiogenesis inhibitors, and PD-L1 inhibitors. The PARP inhibitors and angiogenesis inhibitors segment is expected to account for a key share of the market during the forecast period owing to its increasing use.
Both Zejula and Rubraca, PARP inhibitors, have showed promising outcomes in early trials and compete directly with AstraZeneca's Lynparza.
The utilization of new therapies such as immunotherapy, targeted therapy, and, most critically, combination regimens is the focus of current ovarian cancer research. Immuno-oncologic drugs have showed encouraging outcomes in terms of increased lifespan and reduced toxicity.
However, the single-agent response rate of PD-1/PD-L1 drugs like Opdivo and Keytruda for the treatment of ovarian cancer is less than 20%.
Combination treatments, particularly those that include checkpoint inhibitors, are poised to be launched in the first-line context to address significant unmet requirements such as tumor resistance, progression-free survival, and quality of life.
On the basis of regions, the ovarian cancer drugs market is classified as Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. North America is anticipated to dominate the market during the forecast period.
The regional market growth can be attributed to new product releases, higher acceptance of innovative treatments, a large target population, and a rise in the incidence of ovarian cancer.
On the other hand, Asia Pacific is expected to exhibit a rapid growth rate in the coming years owing to increasing prevalence of ovarian cancer, positive healthcare reforms, growing health awareness, low-cost base, and absence of regulatory and cultural inhibitions in countries such as India and China.
Key players competing in the ovarian cancer drugs market includes AstraZeneca; Roche; Tesaro; Pfizer; AbbVie; ImmunoGen; Johnson & Johnson; Boehringer Ingelheim; Oasmia Pharmaceuticals; and Clovis Oncology. Avastin's market share is expected to be impacted by patent expiration and increased competition from PARP inhibitors.
In the second-line platinum-sensitive scenario, Roche's Tecentriq-based combination therapy is likely to gain momentum as the preferred treatment choice. For advanced-stage patients with BRCA mutations, PARP inhibitors are expected to become the primary maintenance treatment.
When compared to current standard-of-care chemotherapy, the medication class is expected to significantly enhance progression-free survival (PFS). Some of the key business strategies employed by companies includes mergers, acquisitions, partnerships, collaborations, capacity expansion, and product launches to increase their market shares.
For instance, in January 2019, GlaxoSmithKline (GSK), a UK-based pharmaceutical company purchased Tesaro. Tesaro was purchased by GlaxoSmithKline (GSK), a pharmaceutical firm located in the United Kingdom, in January of this year.
With Tesaro's Zejula, a PARP inhibitor, and other Tesaro products, GSK will be able to extend its product portfolio, as well as boost its pharmaceutical business by speeding the development of GSK's pipeline and commercial competence in cancer.