Report Description
NTRK Fusion Gene Positive Advanced Solid Tumors Market Outlook 2031
The Global NTRK Fusion Gene Positive Advanced Solid Tumors Market size was valued at USD 120 million in 2022 and is likely to reach USD 220 million by 2031, expanding at a CAGR of 5.9% during 2023 – 2031. The growth of the market is attributed growing number of patients with NTRK fusion gene-positive tumors.
Increasing number of people affected by cancer is resulting in the growing demand for innovative and targeted treatments which further boosts the NTRK fusion gene-positive advanced solid tumors market. NTRK fusion gene-positive tumors represent a distinct subset of cancer with a specific genetic abnormality. These tumors are relatively rare but can occur in various parts of the body.
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According to a report published by the World Health Organization (WHO) on February 3, 2022, cancer is the leading cause of death globally. In 2020, it was responsible for nearly 10 million deaths, accounting for approximately one in six deaths worldwide. The most common types of cancer are lung, colon, breast, rectal, and prostate cancers.

NTRK fusion gene-positive advanced solid tumors refer to a specific type of cancer that is characterized by the presence of a genetic abnormality known as an NTRK fusion gene. These tumors have certain genes called NTRK genes that fused together leading to the production of abnormal proteins that increase the growth of cancer cells. These tumors occur in various organs and tissues in the body, such as the lungs, thyroid, and colon.
The research report finds that the COVID-19 pandemic hampered the market. The pandemic diverted healthcare resources and attention toward managing the immediate crisis. This has affected the diagnosis, treatment, and research related to NTRK fusion gene-positive tumors. Additionally, clinical trials and research in the field of oncology have been impacted by the pandemic, resulting in slowing down the development of new therapies and treatment strategies for these tumors.
Artificial Intelligence (AI) Impact on NTRK Fusion Gene Positive Advanced Solid Tumors Market
The emergence of artificial intelligence is boosting the market. AI-powered algorithms analyze medical images and genetic data with remarkable precision aiding in the early detection of NTRK fusion gene-positive tumors. Additionally, AI is accelerating research efforts by analyzing vast datasets and identifying patterns for the development of new tumor medicines.
NTRK Fusion Gene Positive Advanced Solid Tumors Market Dynamics
Major Drivers
Rising demand for personalized and tailored treatments is expected to drive the market. Changing lifestyles and environmental factors contribute to a high prevalence of cancer diagnoses, including NTRK fusion gene-positive tumors. This increase in cases drives the demand for specialized treatments tailored to these specific genetic subtypes fueling the market.
Existing Restraints
Lack of skilled laboratory technicians is expected to hamper the market. The shortage of skilled technicians leads to the delays in diagnosing patients with NTRK fusion gene-positive tumors. Additionally, limited awareness among healthcare providers and diagnostic challenges in identifying NTRK fusion gene-positive tumors hinders the market.
Emerging Opportunities
Ongoing innovations in genetic testing and cancer diagnostics technologies are expected to create immense opportunities for the players competing in the market. These advancements lead to early and accurate diagnoses, allowing for prompt initiation of targeted therapies and potentially improving patient outcomes. Furthermore, increasing investment of pharmaceutical companies toward clinical research and trials is propelling the market.

Scope of the NTRK Fusion Gene Positive Advanced Solid Tumors Market Report
The report on the market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes
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Details
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Report Title
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NTRK Fusion Gene Positive Advanced Solid Tumors Market- Global Industry Analysis, Growth, Share, Size, Trends, and Forecast
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Base Year
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2022
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Historic Data
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2016–2021
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Forecast Period
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2023–2031
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Segmentation
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Type (Diagnostics and Therapeutics) and Application (Cancer Centers, Hospitals, Clinics, and Others)
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Regional Scope
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Asia Pacific, North America, Latin America, Europe, and Middle East & Africa
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Report Coverage
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Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, and Trends, and Revenue Forecast
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Key Players Covered in the Report
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Bayer AG; DAIICHI SANKYO COMPANY, LIMITED; Deciphera Pharmaceuticals, Inc; F. Hoffmann-La Roche AG; Glaxosmithkline plc; Merck & Co., Inc.; Pfizer Inc.; and Plexxikon;
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NTRK Fusion Gene Positive Advanced Solid Tumors Market Segment Insights
Type Analysis
Based on type, the NTRK fusion gene positive advanced solid tumors market is divided into diagnostics and therapeutics. The diagnostics segment is expected to hold a major market revenue share of the market during the forecast period due to the increasing number of patients suffering from NTRK fusion gene-positive advanced solid tumors.
Diagnostics are crucial for identifying NTRK fusion gene-positive tumors, as these tumors have specific genetic alterations involving the fusion of NTRK genes. Moreover, diagnosing enables early-stage tumors detection for achieving favorable treatment outcomes, which further boosts the segment.

Application Analysis
On the basis of application, the market is classified as cancer centers, hospitals, clinics, and others. The hospitals segment is anticipated to register robust growth in the coming years, as they are equipped with advanced diagnostic facilities, including rare disease genetic testing and molecular diagnostics laboratories.
These facilities are essential for accurately identifying NTRK fusion gene-positive tumors. Furthermore, hospitals offer specialized treatments to cater to a wide range of solid tumors, which further fuels the segment.
Regional Outlook
In terms of region, the global NTRK fusion gene positive advanced solid tumors market is segmented into Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. North America is expected to dominate the market due to the presence of leading research institutions and pharmaceutical companies.
These companies are at the forefront of developing targeted therapies and conducting clinical trials for these specific tumors. Additionally, growing population suffering from solid tumor conditions propels the market in this region.
The market in Asia Pacific is anticipated to expand at a rapid pace in the coming years due to rising in cancer incidence, including NTRK fusion gene-positive tumors. Factors, such as lifestyle changes, increased life expectancy, and environmental factors fuel the market in the region. This larger patient pool creates a growing market for specialized treatments thrusting market growth.
Segments
The global NTRK fusion gene positive advanced solid tumors market has been segmented on the basis of
Type
Application
- Cancer Centers
- Hospitals
- Clinics
- Others
Region
- Asia Pacific
- North America
- Latin America
- Europe
- Middle East & Africa
Key Players
- Bayer AG
- DAIICHI SANKYO COMPANY, LIMITED
- Deciphera Pharmaceuticals, Inc
- F. Hoffmann-La Roche AG
- Glaxosmithkline plc
- Merck & Co., Inc.
- Pfizer Inc.
- Plexxikon
Competitive Landscape
Key players competing in the global NTRK fusion gene positive advanced solid tumors market are Bayer AG; DAIICHI SANKYO COMPANY, LIMITED; Deciphera Pharmaceuticals, Inc; F. Hoffmann-La Roche AG; Glaxosmithkline plc; Merck & Co., Inc.; Pfizer Inc.; and Plexxikon;
These companies are increasing their market share by adopting various strategies such as partnerships, mergers, reduction in production costs, launching new products, and implementing advanced technologies.
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On January 27th, 2023, Merck & Co., Inc., a multinational pharmaceutical company, announced that their drug KEYTRUDA had received FDA approval. The approval allows for the use of KEYTRUDA in patients who have undergone surgical resection and platinum-based chemotherapy. The treatment is intended for patients with T2a tumors that are larger than or equal to 4 centimeters in size.

Table Of Content
1. Executive Summary
2. Assumptions and Acronyms Used
3. Research Methodology
4. NTRK Fusion Gene Positive Advanced Solid Tumors Market Overview
4.1. Introduction
4.1.1. Market Taxonomy
4.1.2. Market Definition
4.2. Macro-Economic Factors
4.2.1. Industry Outlook
4.3. NTRK Fusion Gene Positive Advanced Solid Tumors Market Dynamics
4.3.1. Market Drivers
4.3.2. Market Restraints
4.3.3. Opportunity
4.3.4. Market Trends
4.4. NTRK Fusion Gene Positive Advanced Solid Tumors Market - Supply Chain
4.5. Global NTRK Fusion Gene Positive Advanced Solid Tumors Market Forecast
4.5.1. NTRK Fusion Gene Positive Advanced Solid Tumors Market Size (US$ Mn) and Y-o-Y Growth
4.5.2. NTRK Fusion Gene Positive Advanced Solid Tumors Market Size (000’ Units) and Y-o-Y Growth
4.5.3. NTRK Fusion Gene Positive Advanced Solid Tumors Market Absolute $ Opportunity
5. Global NTRK Fusion Gene Positive Advanced Solid Tumors Market Analysis and Forecast by Types
5.1. Market Trends
5.2. Introduction
5.2.1. Basis Point Share (BPS) Analysis by Types
5.2.2. Y-o-Y Growth Projections by Types
5.3. NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Types
5.3.1. Diagnostics
5.3.2.
Therapeutics
5.4. Absolute $ Opportunity Assessment by Types
5.5. Market Attractiveness/Growth Potential Analysis by Types
6. Global NTRK Fusion Gene Positive Advanced Solid Tumors Market Analysis and Forecast by Applications
6.1. Market Trends
6.2. Introduction
6.2.1. Basis Point Share (BPS) Analysis by Applications
6.2.2. Y-o-Y Growth Projections by Applications
6.3. NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Applications
6.3.1. Cancer Centers
6.3.2.
Hospitals
6.3.3.
Clinics
6.3.4.
Others
6.4. Absolute $ Opportunity Assessment by Applications
6.5. Market Attractiveness/Growth Potential Analysis by Applications
7. Global NTRK Fusion Gene Positive Advanced Solid Tumors Market Analysis and Forecast by Region
7.1. Market Trends
7.2. Introduction
7.2.1. Basis Point Share (BPS) Analysis by Region
7.2.2. Y-o-Y Growth Projections by Region
7.3. NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Region
7.3.1. North America
7.3.2. Latin America
7.3.3. Europe
7.3.4. Asia Pacific
7.3.5. Middle East and Africa (MEA)
7.4. Absolute $ Opportunity Assessment by Region
7.5. Market Attractiveness/Growth Potential Analysis by Region
7.6. Global NTRK Fusion Gene Positive Advanced Solid Tumors Demand Share Forecast, 2019-2026
8. North America NTRK Fusion Gene Positive Advanced Solid Tumors Market Analysis and Forecast
8.1. Introduction
8.1.1. Basis Point Share (BPS) Analysis by Country
8.1.2. Y-o-Y Growth Projections by Country
8.2. North America NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Country
8.2.1. U.S.
8.2.2. Canada
8.3. Absolute $ Opportunity Assessment by Country
8.4. North America NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Types
8.4.1. Diagnostics
8.4.2.
Therapeutics
8.5. Basis Point Share (BPS) Analysis by Types
8.6. Y-o-Y Growth Projections by Types
8.7. North America NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Applications
8.7.1. Cancer Centers
8.7.2.
Hospitals
8.7.3.
Clinics
8.7.4.
Others
8.8. Basis Point Share (BPS) Analysis by Applications
8.9. Y-o-Y Growth Projections by Applications
8.10. Market Attractiveness/Growth Potential Analysis
8.10.1. By Country
8.10.2. By Product Type
8.10.3. By Application
8.11. North America NTRK Fusion Gene Positive Advanced Solid Tumors Demand Share Forecast, 2019-2026
9. Latin America NTRK Fusion Gene Positive Advanced Solid Tumors Market Analysis and Forecast
9.1. Introduction
9.1.1. Basis Point Share (BPS) Analysis by Country
9.1.2. Y-o-Y Growth Projections by Country
9.1.3. Latin America Average Pricing Analysis
9.2. Latin America NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Country
9.2.1. Brazil
9.2.2. Mexico
9.2.3. Rest of Latin America
9.3. Absolute $ Opportunity Assessment by Country
9.4. Latin America NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Types
9.4.1. Diagnostics
9.4.2.
Therapeutics
9.5. Basis Point Share (BPS) Analysis by Types
9.6. Y-o-Y Growth Projections by Types
9.7. Latin America NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Applications
9.7.1. Cancer Centers
9.7.2.
Hospitals
9.7.3.
Clinics
9.7.4.
Others
9.8. Basis Point Share (BPS) Analysis by Applications
9.9. Y-o-Y Growth Projections by Applications
9.10. Market Attractiveness/Growth Potential Analysis
9.10.1. By Country
9.10.2. By Product Type
9.10.3. By Application
9.11. Latin America NTRK Fusion Gene Positive Advanced Solid Tumors Demand Share Forecast, 2019-2026
10. Europe NTRK Fusion Gene Positive Advanced Solid Tumors Market Analysis and Forecast
10.1. Introduction
10.1.1. Basis Point Share (BPS) Analysis by Country
10.1.2. Y-o-Y Growth Projections by Country
10.1.3. Europe Average Pricing Analysis
10.2. Europe NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Country
10.2.1. Germany
10.2.2. France
10.2.3. Italy
10.2.4. U.K.
10.2.5. Spain
10.2.6. Russia
10.2.7. Rest of Europe
10.3. Absolute $ Opportunity Assessment by Country
10.4. Europe NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Types
10.4.1. Diagnostics
10.4.2.
Therapeutics
10.5. Basis Point Share (BPS) Analysis by Types
10.6. Y-o-Y Growth Projections by Types
10.7. Europe NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Applications
10.7.1. Cancer Centers
10.7.2.
Hospitals
10.7.3.
Clinics
10.7.4.
Others
10.8. Basis Point Share (BPS) Analysis by Applications
10.9. Y-o-Y Growth Projections by Applications
10.10. Market Attractiveness/Growth Potential Analysis
10.10.1. By Country
10.10.2. By Product Type
10.10.3. By Application
10.11. Europe NTRK Fusion Gene Positive Advanced Solid Tumors Demand Share Forecast, 2019-2026
11. Asia Pacific NTRK Fusion Gene Positive Advanced Solid Tumors Market Analysis and Forecast
11.1. Introduction
11.1.1. Basis Point Share (BPS) Analysis by Country
11.1.2. Y-o-Y Growth Projections by Country
11.1.3. Asia Pacific Average Pricing Analysis
11.2. Asia Pacific NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Country
11.2.1. China
11.2.2. Japan
11.2.3. South Korea
11.2.4. India
11.2.5. Australia
11.2.6. Rest of Asia Pacific (APAC)
11.3. Absolute $ Opportunity Assessment by Country
11.4. Asia Pacific NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Types
11.4.1. Diagnostics
11.4.2.
Therapeutics
11.5. Basis Point Share (BPS) Analysis by Types
11.6. Y-o-Y Growth Projections by Types
11.7. Asia Pacific NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Applications
11.7.1. Cancer Centers
11.7.2.
Hospitals
11.7.3.
Clinics
11.7.4.
Others
11.8. Basis Point Share (BPS) Analysis by Applications
11.9. Y-o-Y Growth Projections by Applications
11.10. Market Attractiveness/Growth Potential Analysis
11.10.1. By Country
11.10.2. By Product Type
11.10.3. By Application
11.11. Asia Pacific NTRK Fusion Gene Positive Advanced Solid Tumors Demand Share Forecast, 2019-2026
12. Middle East & Africa NTRK Fusion Gene Positive Advanced Solid Tumors Market Analysis and Forecast
12.1. Introduction
12.1.1. Basis Point Share (BPS) Analysis by Country
12.1.2. Y-o-Y Growth Projections by Country
12.1.3. Middle East & Africa Average Pricing Analysis
12.2. Middle East & Africa NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Country
12.2.1. Saudi Arabia
12.2.2. South Africa
12.2.3. UAE
12.2.4. Rest of Middle East & Africa (MEA)
12.3. Absolute $ Opportunity Assessment by Country
12.4. Middle East & Africa NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Types
12.4.1. Diagnostics
12.4.2.
Therapeutics
12.5. Basis Point Share (BPS) Analysis by Types
12.6. Y-o-Y Growth Projections by Types
12.7. Middle East & Africa NTRK Fusion Gene Positive Advanced Solid Tumors Market Size and Volume Forecast by Applications
12.7.1. Cancer Centers
12.7.2.
Hospitals
12.7.3.
Clinics
12.7.4.
Others
12.8. Basis Point Share (BPS) Analysis by Applications
12.9. Y-o-Y Growth Projections by Applications
12.10. Market Attractiveness/Growth Potential Analysis
12.10.1. By Country
12.10.2. By Product Type
12.10.3. By Application
12.11. Middle East & Africa NTRK Fusion Gene Positive Advanced Solid Tumors Demand Share Forecast, 2019-2026
13. Competition Landscape
13.1. Global NTRK Fusion Gene Positive Advanced Solid Tumors Market: Market Share Analysis
13.2. NTRK Fusion Gene Positive Advanced Solid Tumors Distributors and Customers
13.3. NTRK Fusion Gene Positive Advanced Solid Tumors Market: Competitive Dashboard
13.4. Company Profiles (Details: Overview, Financials, Developments, Strategy)
13.4.1. Bayer AG
13.4.2.
DAIICHI SANKYO COMPANY, LIMITED
13.4.3.
Deciphera Pharmaceuticals, Inc
13.4.4.
F. Hoffmann-La Roche AG
13.4.5.
Glaxosmithkline plc
13.4.6.
Merck & Co., Inc.
13.4.7.
Pfizer Inc.
13.4.8.
Plexxikon