Myelodysplastic Syndrome Drugs Market

Myelodysplastic Syndrome Drugs Market

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Author:

Raksha Sharma

Vineet

Fact-checked by:

Vineet Pandey

Shreyas

Editor:

Shreyas Tandon

Myelodysplastic Syndrome Drugs Market Outlook 2031

The global myelodysplastic syndrome drugs market size was valued at USD 2.27 Billion in 2022 and is expected to reach USD 5.22 Billion by 2031, expanding at a CAGR of 9.7% during the forecast period, 2023–2031. The growth of the market is attributed to the rising presence of novel therapeutics, improving healthcare services, and growing geriatric population. 

Myelodysplastic syndrome (MDS) is caused due to mutation of one or more genes which control the blood cells development. It is a common type of malignant hematological diseases. Every year it is affecting around five out of every 100,000 people in the US.

Myelodysplastic Syndrome Drugs Market Outlook

Around 60,000 people live with MDS in the U.S. and every year around 12,000-15,000 new cases are getting reported. Patients are present with clinical manifestations including anemia, thrombocytopenia, and neutropenia. There are some factors such as heavy metals (including mercury and lead) and exposure to chemicals (includes pesticides, tobacco, and benzene) are activating the disease onset.

Currently, demand of hypomethylating agents is rising because of approval and adoption of Vidaza and Dacogen. Huge pipeline including Aranesp is anticipated to aid the market in the coming years. Easy accessibility and availability of new treatments in developed countries gives opportunity to the market.

The non-profit health organization such as MDS International Foundation support psychologically along with funding for the treatment of the patients. 
Globally, increase in geriatric population as MDS is generally found in this population due to which disease remains incurable.

Therefore, substantial progress is made in MDS diagnosis by using sequencing technologies. Using this technology chromosomal abnormalities in MDS patients are identified. Available therapies are efficacious, but commonly they are not curative.

Due to high cost of therapeutics, several affordable healthcare measures were implemented across all key markets and affecting major market players. Currently, stem cell transplant is the only cure for myelodysplastic syndrome. But, it includes high risk and patients with medical complications are not eligible.

Myelodysplastic Syndrome Drugs Market Trends, Drivers, Restraints, and Opportunities

  • Growing prevalence of myelodysplastic syndrome and rising geriatric population are projected to drive the growth of the market over the forecast period.
  • Favorable government initiatives is expected to push the growth of the market over the forecast period.
  • Rising incidence of niche indications and improvement in healthcare services are anticipated to fuel the expansion of the market.
  • Increasing awareness about disease among people and easy reimbursement policies are estimated to boost the market expansion in the coming years.
  • Rising development of novel therapeutics is one of the major factor propelling the market expansion in the coming years.
  • High cost of drugs and several side effects are major factor responsible for hampering the market growth over the forecast period.

Scope of Myelodysplastic Syndrome Drugs Market Report

The report on the global myelodysplastic syndrome drugs market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.

Attributes

Details

Report Title

Myelodysplastic Syndrome Drugs Market - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast

Base Year

2022

Historic Data

2016–2021

Forecast Period

2023–2031

Segmentation

Therapeutic Classes (Hypomethylating Agents, Immunomodulatory Drugs, and Anti-anemics)

Regional Scope

Asia Pacific, North America, Latin America, Europe, and Middle East & Africa

Report Coverage

Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, and Trends, and Revenue Forecast

Key Players Covered in the Report

Celgene; Amgen; Otsuka; Mylan N.V.; Pfizer, Inc.; Takeda; AbbVie; Dr. Reddy's Laboratories; Accord Healthcare; Bristol-Myers Squibb; Sandoz, Inc.; and Novartis AG

Myelodysplastic Syndrome Drugs Market Segment Insights

Therapeutic Classes Segment Analysis

Based on therapeutic classes, the myelodysplastic syndrome drugs market is divided into hypomethylating agents, immunomodulatory drugs, and anti-anemics. The immunomodulatory drugs segment is expected to hold a key share of the market during the forecast period owing to lack of generic competition and increasing adoption of therapeutics.

Only one approved treatment for low-risk MDS is Revlimid (lenalidomide). 
On the other hand, the hypomethylating agents segment is anticipated to expand at a rapid pace during the forecast period. Hypomethylating agents includes Celgene’s Vidaza and Otsuka’s Dacogen, which are used as a first line of treatment for high-risk patients.

Also, anti-anemics drug segment is increasing at significant pace. Celgene’s luspatercept and Amgen’s Aranesp are under investigation in clinical trials of treatments. Usage of anti-anemics drug aids rising RBC count in the blood, hence decreases the requirement of frequent blood transfusions.

Myelodysplastic Syndrome Drugs Market Therapeutic Classes

Regional Outlook

On the basis of regions, the myelodysplastic syndrome drugs market is classified as Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. The market of North America is anticipated to dominate the market during the forecast period.

The regional market growth can be attributed to multiple product launches in the region. Moreover, rising adoption of novel therapies, high cost of treatment, and presence of a large cohort in the U.S. are expected to fuel the regional market growth.

Myelodysplastic Syndrome Drugs Market Region

Segments

The global myelodysplastic syndrome drugs market has been segmented on the basis of

Therapeutic classes

  • Hypomethylating Agents
  • Immunomodulatory Drugs
  • Anti-anemics

Regions

  • Asia Pacific
  • North America
  • Latin America
  • Europe
  • Middle East & Africa

Key Players

  • Celgene
  • Amgen
  • Otsuka
  • Mylan N.V.
  • Pfizer, Inc.
  • Takeda
  • AbbVie
  • Dr. Reddy's Laboratories
  • Accord Healthcare
  • Bristol-Myers Squibb
  • Sandoz, Inc.
  • Novartis AG

Competitive Landscape

Key players competing in the myelodysplastic syndrome drugs market include Celgene; Amgen; Otsuka; Mylan N.V.; Pfizer, Inc.; Takeda; AbbVie; Dr. Reddy's Laboratories; Accord Healthcare; Bristol-Myers Squibb; Sandoz, Inc.; and Novartis AG.

Major market player are adopting several market strategies such as mergers, acquisitions, partnerships, collaborations, capacity expansion, and product launches to enhance their market shares.

Myelodysplastic Syndrome Drugs Market Key Players

1. Executive Summary
2. Assumptions and Acronyms Used
3. Research Methodology
4. Myelodysplastic Syndrome Drugs Market Overview
  4.1. Introduction
     4.1.1. Market Taxonomy
     4.1.2. Market Definition
  4.2. Macro-Economic Factors
     4.2.1. Industry Outlook
  4.3. Myelodysplastic Syndrome Drugs Market Dynamics
     4.3.1. Market Drivers
     4.3.2. Market Restraints
     4.3.3. Opportunity
     4.3.4. Market Trends
  4.4. Myelodysplastic Syndrome Drugs Market - Supply Chain
  4.5. Global Myelodysplastic Syndrome Drugs Market Forecast
     4.5.1. Myelodysplastic Syndrome Drugs Market Size (US$ Mn) and Y-o-Y Growth
     4.5.2. Myelodysplastic Syndrome Drugs Market Size (000’ Units) and Y-o-Y Growth
     4.5.3. Myelodysplastic Syndrome Drugs Market Absolute $ Opportunity
5. Global Myelodysplastic Syndrome Drugs Market Analysis and Forecast by Region
  5.1. Market Trends
  5.2. Introduction
     5.2.1. Basis Point Share (BPS) Analysis by Region
     5.2.2. Y-o-Y Growth Projections by Region
  5.3. Myelodysplastic Syndrome Drugs Market Size and Volume Forecast by Region
     5.3.1. North America
     5.3.2. Latin America
     5.3.3. Europe
     5.3.4. Asia Pacific
     5.3.5. Middle East and Africa (MEA)
  5.4. Absolute $ Opportunity Assessment by Region
  5.5. Market Attractiveness/Growth Potential Analysis by Region
  5.6. Global Myelodysplastic Syndrome Drugs Demand Share Forecast, 2019-2026
6. North America Myelodysplastic Syndrome Drugs Market Analysis and Forecast
  6.1. Introduction
     6.1.1. Basis Point Share (BPS) Analysis by Country
     6.1.2. Y-o-Y Growth Projections by Country
  6.2. North America Myelodysplastic Syndrome Drugs Market Size and Volume Forecast by Country
     6.2.1. U.S.
     6.2.2. Canada
  6.3. Absolute $ Opportunity Assessment by Country
  6.4. Market Attractiveness/Growth Potential Analysis
     6.4.1. By Country
     6.4.2. By Product Type
     6.4.3. By Application
  6.5. North America Myelodysplastic Syndrome Drugs Demand Share Forecast, 2019-2026
7. Latin America Myelodysplastic Syndrome Drugs Market Analysis and Forecast
  7.1. Introduction
     7.1.1. Basis Point Share (BPS) Analysis by Country
     7.1.2. Y-o-Y Growth Projections by Country
     7.1.3. Latin America Average Pricing Analysis
  7.2. Latin America Myelodysplastic Syndrome Drugs Market Size and Volume Forecast by Country
      7.2.1. Brazil
      7.2.2. Mexico
      7.2.3. Rest of Latin America
   7.3. Absolute $ Opportunity Assessment by Country
  7.4. Market Attractiveness/Growth Potential Analysis
     7.4.1. By Country
     7.4.2. By Product Type
     7.4.3. By Application
  7.5. Latin America Myelodysplastic Syndrome Drugs Demand Share Forecast, 2019-2026
8. Europe Myelodysplastic Syndrome Drugs Market Analysis and Forecast
  8.1. Introduction
     8.1.1. Basis Point Share (BPS) Analysis by Country
     8.1.2. Y-o-Y Growth Projections by Country
     8.1.3. Europe Average Pricing Analysis
  8.2. Europe Myelodysplastic Syndrome Drugs Market Size and Volume Forecast by Country
     8.2.1. Germany
     8.2.2. France
     8.2.3. Italy
     8.2.4. U.K.
     8.2.5. Spain
     8.2.6. Russia
     8.2.7. Rest of Europe
  8.3. Absolute $ Opportunity Assessment by Country
  8.4. Market Attractiveness/Growth Potential Analysis
     8.4.1. By Country
     8.4.2. By Product Type
     8.4.3. By Application
  8.5. Europe Myelodysplastic Syndrome Drugs Demand Share Forecast, 2019-2026
9. Asia Pacific Myelodysplastic Syndrome Drugs Market Analysis and Forecast
  9.1. Introduction
     9.1.1. Basis Point Share (BPS) Analysis by Country
     9.1.2. Y-o-Y Growth Projections by Country
     9.1.3. Asia Pacific Average Pricing Analysis
  9.2. Asia Pacific Myelodysplastic Syndrome Drugs Market Size and Volume Forecast by Country
     9.2.1. China
     9.2.2. Japan
     9.2.3. South Korea
     9.2.4. India
     9.2.5. Australia
     9.2.6. Rest of Asia Pacific (APAC)
  9.3. Absolute $ Opportunity Assessment by Country
  9.4. Market Attractiveness/Growth Potential Analysis
     9.4.1. By Country
     9.4.2. By Product Type
     9.4.3. By Application
  9.5. Asia Pacific Myelodysplastic Syndrome Drugs Demand Share Forecast, 2019-2026
10. Middle East & Africa Myelodysplastic Syndrome Drugs Market Analysis and Forecast
  10.1. Introduction
     10.1.1. Basis Point Share (BPS) Analysis by Country
     10.1.2. Y-o-Y Growth Projections by Country
     10.1.3. Middle East & Africa Average Pricing Analysis
  10.2. Middle East & Africa Myelodysplastic Syndrome Drugs Market Size and Volume Forecast by Country
     10.2.1. Saudi Arabia
     10.2.2. South Africa
     10.2.3. UAE
     10.2.4. Rest of Middle East & Africa (MEA)
  10.3. Absolute $ Opportunity Assessment by Country
  10.4. Market Attractiveness/Growth Potential Analysis
     10.4.1. By Country
     10.4.2. By Product Type
     10.4.3. By Application
  10.5. Middle East & Africa Myelodysplastic Syndrome Drugs Demand Share Forecast, 2019-2026
11. Competition Landscape
  11.1. Global Myelodysplastic Syndrome Drugs Market: Market Share Analysis
  11.2. Myelodysplastic Syndrome Drugs Distributors and Customers
  11.3. Myelodysplastic Syndrome Drugs Market: Competitive Dashboard
  11.4. Company Profiles (Details: Overview, Financials, Developments, Strategy)
     11.4.1. Celgene
     11.4.2. Amgen
     11.4.3. Otsuka
     11.4.4. Mylan N.V.
     11.4.5. Pfizer, Inc.
     11.4.6. Takeda
     11.4.7. AbbVie
     11.4.8. Dr. Reddy's Laboratories
     11.4.9. Accord Healthcare
     11.4.10. Bristol-Myers Squibb
     11.4.11. Sandoz, Inc.

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