Segments - by Disease Type (Wet AMD, Dry AMD, Diabetic Retinopathy, Retinal Vein Occlusion, Diabetic Macular Edema, Others), by Treatment Type (Surgical Treatments, Intraocular Implants, Pharmacological Treatments), by Drug Class (Anti-VEGF Agents, Retinoids, Corticosteroids, Gene Therapy), by End-user (Hospitals, Specialty Clinics, Ambulatory Surgical Centers, Others)
The global macular degeneration (AMD) and other retinal diseases market size was USD 8.9 billion in 2023 and is likely to reach USD 15.4 billion by 2032, expanding at a CAGR of 6.5% during 2024–2032. The market growth is attributed to home-based retinal monitoring and patient-centered care.
Age-related macular degeneration (AMD) and other retinal diseases are a group of vision-impairing conditions that affect the retina the light-sensitive tissue at the back of the eye. AMD primarily impacts the macula, which is responsible for central vision and fine detail, and it is categorized into wet (neovascular) and dry (atrophic). Other significant retinal diseases include diabetic retinopathy, retinal vein occlusion, and diabetic macular edema, all of which lead to progressive vision loss if untreated. These conditions are often linked to aging, diabetes, or vascular problems and require specialized medical management.
Home-based retinal monitoring is gaining traction as a key trend in the AMD and other retinal diseases market, especially with the rise of portable, easy-to-use devices for retinal imaging and monitoring. These devices enable patients to track their condition from the comfort of their homes, reducing the need for frequent in-person visits and enhancing treatment adherence. Additionally, the trend toward patient-centered care is reshaping how retinal diseases are managed. By focusing on personalized care plans, patient preferences, and improved communication between patients and healthcare providers, there is a greater emphasis on improving quality of life and outcomes. These trends are expected to drive efficient and accessible care, particularly for those with chronic or age-related retinal conditions.
The global rise in the aging population is one of the primary drivers of the AMD and other retinal diseases market, as these conditions are strongly age-related. As life expectancy increases worldwide, especially in developed and emerging economies, the number of individuals over the age of 60 continues to grow heightening the prevalence of age-related vision disorders such as macular degeneration. Older adults are susceptible to degenerative changes in the retina, leading to an expanding patient pool in need of ongoing ophthalmic care and therapeutic interventions.
Rapid innovations in retinal treatment technologies have significantly boosted market growth. Breakthroughs such as anti-VEGF injections, sustained-release intraocular implants, laser-based therapies, and emerging gene and cell therapies are transforming patient outcomes and clinical practices. These advancements allow for earlier detection, more effective disease management, and less frequent dosing, which improves patient compliance. Demand for novel and personalized treatment solutions continues to rise, attracting investment and driving competition among biotech and pharmaceutical companies.
The increasing global incidence of retinal diseases driven by factors such as diabetes, hypertension, and unhealthy lifestyles is contributing to the growing demand for retinal disease management. Diabetic retinopathy and diabetic macular edema, in particular, are on the rise due to the global diabetes epidemic. In addition, retinal vein occlusion and age-related macular degeneration are becoming common, leading to a surge in diagnosis rates and a greater need for long-term treatment. This rising burden has heightened awareness among healthcare providers and patients, further propelling market expansion.
The high cost associated with the diagnosis, treatment, and ongoing management of retinal diseases is a major barrier to wider market adoption, especially in lower-income populations. Anti-VEGF therapies, which are the standard of care for conditions such as wet AMD and diabetic macular edema, require frequent intravitreal injections often monthly leading to substantial cumulative expenses. Additionally, advanced surgical procedures and imaging diagnostics such as optical coherence tomography (OCT) add to the financial burden. For many patients, especially those without comprehensive insurance coverage, the cost is prohibitive, limiting treatment adherence and overall outcomes.
Limited access to quality eye care and advanced retinal treatments remains significantly limited in many developing and under-resourced regions. Factors such as inadequate healthcare infrastructure, shortage of trained ophthalmologists, and lack of awareness about retinal diseases contribute to delayed diagnosis and undertreatment. In rural areas, even basic screening services are unavailable, and logistical challenges further hinder regular follow-up care. This disparity in access prevents a large segment of the global population from benefiting from the latest therapeutic advancements, thereby restraining overall market growth in these regions.
Expansion in emerging markets such as India, China, Brazil, and parts of Southeast Asia and Africa offers significant growth potential due to improving healthcare infrastructure, rising disposable incomes, and growing awareness about eye health. As these countries invest in healthcare systems and universal insurance schemes, access to diagnostic services and advanced treatments is expected to increase. Furthermore, the large and aging populations in these regions create a vast, underserved patient base. Pharmaceutical companies are recognizing this opportunity and expanding their footprint through localized manufacturing, strategic partnerships, and affordable treatment models tailored to regional needs.
The development of gene and cell therapies presents a transformative opportunity in the treatment of retinal diseases, particularly for conditions such as inherited retinal dystrophies and advanced AMD that currently have limited or no cure. These therapies aim to address the root causes of disease at the genetic level or regenerate damaged retinal tissue, offering the possibility of long-term or permanent vision restoration. Recent FDA approvals and promising clinical trial results are accelerating interest and investment in this space. As research progresses and regulatory pathways become clearer, gene and cell therapies are expected to become a major growth driver in the coming decade.
The market report includes an assessment of the market trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes |
Details |
Report Title |
Macular Degeneration (AMD) and Other Retinal Diseases Market - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast |
Base Year |
2023 |
Historic Data |
2017 -2022 |
Forecast Period |
2024–2032 |
Segmentation |
Disease Type (Wet AMD, Dry AMD, Diabetic Retinopathy, Retinal Vein Occlusion, Diabetic Macular Edema, and Others), Treatment Type (Surgical Treatments, Intraocular Implants, and Pharmacological Treatments), Drug Class (Anti-VEGF Agents, Retinoids, Corticosteroids, and Gene Therapy), and End-user (Hospitals, Specialty Clinics, Ambulatory Surgical Centers, and Others) |
Regional Scope |
Asia Pacific, North America, Latin America, Europe, and Middle East & Africa |
Report Coverage |
Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, Market Trends, and Revenue Forecast |
Key Players Covered in the Report |
Regeneron Pharmaceuticals Inc., F. Hoffmann-La Roche Ltd, Novartis AG, Bayer AG, Pfizer Inc., Bausch Health Companies Inc., Apellis Pharmaceuticals, Santen Pharmaceutical Co., Ltd., Adverum Biotechnologies, Inc., and Allergan (AbbVie Inc.) |
North America holds the largest share of the AMD and other retinal diseases market, with the US being the dominant contributor. The prevalence of age-related macular degeneration (AMD) and other retinal diseases is notably high in this region due to the aging population. The US benefits from advanced healthcare infrastructure, widespread access to specialized ophthalmologists, and a strong focus on research and development, particularly in the areas of gene therapies and advanced biologics. Canada plays a significant role, with increasing awareness, government healthcare programs, and growing investments in ophthalmology innovations. Regulatory bodies such as the FDA have approved several novel treatments, including anti-VEGF therapies, which have further driven the market growth in this region.
Europe is a prominent region for the AMD and other retinal diseases market, led by Germany, the UK, and France. The aging population across European countries contributes to the rising demand for AMD treatments. Germany is one of the leading countries, with a strong healthcare system and high spending on retinal care. The UK and France exhibit substantial market growth due to their robust healthcare systems, ongoing clinical trials, and the availability of advanced treatments. European healthcare policy and reimbursement structures significantly influence the market, with increasing adoption of novel therapies and improved access to treatment in many countries. Thus, in turn, is expected to boost the market in the region.
Asia Pacific is expected to witness substantial growth in the AMD and other retinal diseases market in the coming years. Japan holds a significant share of the market, driven by its aging population and well-established healthcare system that supports the adoption of advanced treatments. China and India represent high-growth opportunities due to their large populations and rising prevalence of retinal conditions. These markets are witnessing significant investments in healthcare infrastructure, including the expansion of specialized eye care centers. The increasing economic power of these nations, combined with government healthcare initiatives, is driving the adoption of innovative treatments such as anti-VEGF agents. APAC, including countries such as South Korea and Australia, contributes to the region's growth due to improving healthcare access and a growing focus on retinal disease management.
Wet AMD is the dominant segment within the AMD and other retinal diseases market. This condition involves the growth of abnormal blood vessels beneath the retina, leading to rapid vision loss. The high prevalence of wet AMD among the aging population, coupled with its severe impact on vision, has driven significant demand for effective treatments. Therapeutic options such as anti-VEGF (vascular endothelial growth factor) therapies have been central to managing this condition. The continuous need for frequent injections and the associated healthcare costs have contributed to wet AMD's substantial market share.
Dry AMD is anticipated to experience the highest growth rate in the coming years. This form of AMD is characterized by the gradual breakdown of retinal cells, leading to vision impairment. The increasing global elderly population is a significant factor driving the rise in dry AMD cases. Recent advancements in research and development, along with the introduction of new therapies, are expected to enhance treatment outcomes and patient quality of life, thereby expanding the market share of dry AMD.
Pharmacological treatments dominated the AMD and other retinal diseases market, due to the widespread use of anti-VEGF (vascular endothelial growth factor) therapies such as Eylea (aflibercept), Lucentis (ranibizumab), and Beovu (brolucizumab). These injectable medications are considered the standard of care for conditions such as wet AMD, diabetic macular edema, and retinal vein occlusion. Their effectiveness in reducing retinal fluid accumulation and preserving vision has led to their extensive adoption across healthcare settings. However, challenges such as the high cost of branded drugs and the growing availability of biosimilars are influencing market dynamics.
Intraocular implants are anticipated to experience significant growth in the coming years. These implants offer sustained drug delivery, reducing the frequency of injections required for conditions such as wet AMD and diabetic macular edema. The development of innovative implants that provide long-term therapeutic effects is expected to enhance patient compliance and treatment outcomes, thereby driving the segment's expansion.
Anti-VEGF (vascular endothelial growth factor) agents dominated the AMD and other retinal diseases market. This dominance is attributed to the high efficacy of anti-VEGF therapies in treating conditions such as wet AMD, diabetic macular edema, and retinal vein occlusion. Medications such as aflibercept (Eylea), ranibizumab (Lucentis), and brolucizumab (Beovu) have become standard treatments due to their ability to inhibit abnormal blood vessel growth and leakage in the retina. The widespread adoption of these therapies has significantly contributed to their market leadership.
Gene therapy is projected to witness substantial growth during the forecast period. This innovative approach aims to provide long-term solutions by delivering genes that produce therapeutic proteins directly within the eye, reducing the need for frequent injections. Advancements in gene delivery technologies and promising clinical trial results are driving interest in this segment. The development of gene therapies targeting retinal diseases holds the potential to revolutionize treatment paradigms, offering sustained efficacy and improved patient compliance.
Hospitals held the largest share of the AMD and other retinal diseases market. This dominance is attributed to the comprehensive care hospitals provide, including advanced diagnostic tools, specialized ophthalmologists, and the ability to administer complex treatments such as intravitreal injections for wet AMD. The high prevalence of age-related macular degeneration (AMD) among the elderly population and the increasing number of hospital admissions for retinal conditions have further solidified hospitals' leading position in the market.
Specialty clinics are projected to experience significant growth in the coming years. These clinics offer focused expertise in retinal diseases, providing patients with personalized care and specialized treatments. The increasing demand for specialized services, coupled with advancements in diagnostic and therapeutic technologies, is driving the expansion of specialty clinics. Additionally, the convenience and accessibility of these clinics are attracting a growing patient base seeking targeted care for retinal conditions.
The macular degeneration (AMD) and other retinal diseases market has been segmented on the basis of
Key players competing in the global macular degeneration (AMD) and other retinal diseases market are Regeneron Pharmaceuticals Inc., F. Hoffmann-La Roche Ltd, Novartis AG, Bayer AG, Pfizer Inc., Bausch Health Companies Inc., Apellis Pharmaceuticals, Santen Pharmaceutical Co., Ltd., Adverum Biotechnologies, Inc., and Allergan (AbbVie Inc.)
These companies use development strategies including mergers, acquisitions, partnerships, collaboration, and product launches to expand their consumer base worldwide.