Segments - Hereditary Angioedema Therapeutic Market by Drug Classes (C1-Esterase Inhibitor, Bradykinin B2 Receptor Antagonist, Kallikrein Inhibitor, and Others), Treatment Types (Prophylaxis and On-Demand), Routes of Administration (Intravenous, Subcutaneous, and Oral), and Regions (Asia Pacific, North America, Latin America, Europe and Middle East & Africa)- Global Industry Analysis, Growth, Share, Size, Trends, and Forecast 2023 – 2031
The Hereditary Angioedema Therapeutic Market size was USD 3.30 Billion in 2022 and is likely to reach USD 6.27 Billion by 2031, expanding at a CAGR of 7.4% during 2023–2031. The growth of the market is attributed to the increasing number of cases for hereditary angioedema.
Hereditary angioedema is a genetic disorder characterized from multiple recurring episodes of swelling known as angioedema. These swells happen in certain areas of the body such as the limbs, intestinal tract, airway, and face. Normally stress to minor trauma can trigger an attack, but swelling of the limbs can take place without known triggers.
The swelling in the airway is especially dangerous considering it can restrict the host’s breathing leading to life-threatening obstruction. Mutation in genes can cause hereditary angioedema which can vary upon individuals. People facing malnutrition or people with limited immunities are more susceptible to this disease over others.
According to the World Health Organization or the WHO and the National Organization for Rare Disorders or the NORD census report, about one in every nine people in any environment or condition can be affected by hereditary angioedema.
The COVID-19 pandemic has reduced the growth of the global hereditary angioedema therapeutic market initially. However, upon further studies, researchers and scientists found out that the coronavirus has the viral gene of accelerating illness of the hosts. Basically, a patient of hereditary angioedema was more susceptible to the COVID-19 virus than that of a healthy person. This steered to hospitals, clinics, and healthcare laboratories to focus more on hereditary angioedema therapies for the prevention and treatment of diseases and this led to its market growth in the later stages of this pandemic.
The report on the global hereditary angioedema therapeutic market size includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes |
Details |
Report Title |
Hereditary Angioedema Therapeutic Market Size - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast |
Base Year |
2022 |
Historic Data |
2016–2021 |
Forecast Period |
2023–2031 |
Segmentation |
Drug Classes (C1-Esterase Inhibitor, Bradykinin B2 Receptor Antagonist, Kallikrein Inhibitor, and Others), Treatment Types (Prophylaxis and On-Demand), Routes of Administration (Intravenous, Subcutaneous, and Oral) |
Regional Scope |
Asia Pacific, North America, Latin America, Europe, and Middle East & Africa |
Report Coverage |
Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, Trends, and Revenue Forecast |
Key Players Covered in the Report |
BioCryst Pharmaceuticals Inc; Ionis Pharmaceuticals Inc; Pharming Group N.V; CSL Limited; Shire Plc; Attune Pharmaceuticals Inc; Adverum Biotechnologies Inc; and KalVista Pharmaceuticals Inc |
Based on drug classes, the global hereditary angioedema therapeutic market is segmented into C1-esterase inhibitor, Bradykinin B2 receptor antagonist, Kallikrein inhibitor, and others. The C1-esterase inhibitor segment is expected to constitute the major share of the market in 2019 and is anticipated to grow with a significant CAGR during the forecast period, 2023-2031. The major reason attributed to the dominant share of this segment is the products used for this treatment which has both prophylactic & on-demand treatment for hereditary angioedema.
Based on treatment types, the global hereditary angioedema therapeutic market is bifurcated into prophylaxis and on-demand. The on-demand segment is expected to constitute the major share of the market in 2019 and is anticipated to grow with a significant CAGR during the forecast period, 2023-2031. The major reason for this segment growth is attributed to continuous usage of on-demand products for the management of acute & chronic hereditary angioedema attacks.
This method is also been preferred in almost all parts of the world and this segment is observing a geographical expansion.
Based on the routes of administration, the global hereditary angioedema therapeutic market is divided into intravenous, subcutaneous, and oral. The intravenous segment is expected to constitute the major share of the market in 2019. The major reason attributing to this market growth is that the existing therapies used for the treatment of hereditary angioedema have been mostly administered by intravenous methods.
Meanwhile the subcutaneous segment is anticipated to grow with a significant CAGR during the forecast period, 2023-2031. Patients have started to find difficulties to frequent intravenous methods causing hardships in their immunity levels. Subcutaneous have found superior advantages be it in time, money, efficiency, or efficacy.
On the basis of regions, the global hereditary angioedema therapeutic market is categorized as Asia Pacific, North America, Latin America, Europe and Middle East & Africa. The market in North America is expected to constitute the largest share in 2019. This regional market growth can be attributed to the growing research & development expenditure along with the rising in adoption of the latest technology.
The demand of hereditary angioedema therapies is increasing rapidly in this region due to the presence of the major market players in the market, an advantage no other region has. The cost of expenditure is significantly lower in North America than that of other economies. However, the market in Asia Pacific is anticipated to expand at a significant CAGR during the forecast period, 2023-2031, as they have prioritized the cost-efficiency perspective of hereditary angioedema therapies combined with their growing population.
The global hereditary angioedema therapeutic market size has been segmented in terms of
Major players competing in the global hereditary angioedema therapeutic market are BioCryst Pharmaceuticals Inc; Ionis Pharmaceuticals Inc; Pharming Group N.V; CSL Limited; Shire Plc; Attune Pharmaceuticals Inc; Adverum Biotechnologies Inc; and KalVista Pharmaceuticals Inc. These market players are involved in several business strategies such as mergers, acquisitions partnerships, collaborations, capacity expansion, and product launches to enhance their market shares.
Pharming Group N.V has appointed Inceptua Medicines Access to be their new business & distribution partner for the hereditary angioedema global access program in September 2019. This deal was aimed to help patients across geographies where hereditary angioedema is not available commercially so that every patient has access through ethical mechanisms and regulatory compliant to the products Pharming Group N.V provide.