Hereditary Angioedema Therapeutic Market Research Report 2033

Hereditary Angioedema Therapeutic Market Research Report 2033

Segments - by Drug Class (C1 Esterase Inhibitors, Kallikrein Inhibitors, Bradykinin Receptor Antagonists, Others), by Route Of Administration (Oral, Intravenous, Subcutaneous), by Treatment Type (On-Demand, Prophylaxis), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies)

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Report Description


Hereditary Angioedema Therapeutics Market Outlook

As per our latest research, the global hereditary angioedema therapeutics market size reached USD 2.38 billion in 2024, driven by increasing disease awareness, novel drug approvals, and expanding therapeutic options. The market is anticipated to grow at a robust CAGR of 8.7% through the forecast period, reaching a projected value of USD 5.01 billion by 2033. This sustained growth is primarily attributed to the rising prevalence of hereditary angioedema (HAE), greater patient access to advanced treatments, and ongoing innovation in targeted therapies.

The hereditary angioedema therapeutics market is experiencing significant momentum due to a confluence of factors, the most notable being the increasing diagnosis rates of HAE worldwide. Historically, HAE has been underdiagnosed due to its rarity and symptom overlap with other conditions. However, improved genetic screening, heightened physician awareness, and patient education campaigns have led to earlier and more accurate diagnoses. This, in turn, has driven up demand for effective therapies that can both manage acute attacks and provide long-term prophylaxis. Additionally, the development and approval of new drug classes, such as kallikrein inhibitors and bradykinin receptor antagonists, have expanded the therapeutic arsenal, offering patients more individualized and effective treatment options.

Another pivotal growth driver for the hereditary angioedema therapeutics market is the increasing focus on patient-centric care and convenience in drug administration. Pharmaceutical companies are investing heavily in the development of therapies that can be self-administered, such as subcutaneous formulations and oral medications, minimizing the need for hospital visits and improving patient quality of life. The shift from intravenous to subcutaneous and oral routes has not only enhanced therapeutic compliance but also broadened the patient pool eligible for treatment. Furthermore, advancements in biotechnology and the introduction of recombinant therapies have improved the safety and efficacy profiles of HAE drugs, further propelling market growth.

The market's expansion is also fueled by favorable reimbursement policies and growing healthcare expenditure, particularly in developed regions such as North America and Europe. Governments and private insurers are increasingly recognizing the burden of HAE and the cost-effectiveness of early intervention and prophylactic treatment. This has led to broader insurance coverage for HAE therapies, reducing out-of-pocket expenses for patients and boosting market uptake. Moreover, the entry of biosimilars and generic versions of established drugs is expected to enhance competition, drive down costs, and increase accessibility in emerging markets, thereby sustaining the market's upward trajectory.

From a regional perspective, North America currently dominates the hereditary angioedema therapeutics market, accounting for the largest share in 2024, followed by Europe and Asia Pacific. The United States, in particular, benefits from a well-established healthcare infrastructure, high disease awareness, and rapid adoption of novel therapies. Europe also holds a significant market share, supported by strong regulatory frameworks and comprehensive healthcare systems. Meanwhile, Asia Pacific is emerging as a high-growth region, fueled by increasing healthcare investments, rising patient awareness, and expanding pharmaceutical distribution networks. These regional dynamics are expected to shape the market landscape over the coming decade.

Global Hereditary Angioedema Therapeutic Industry Outlook

Drug Class Analysis

The hereditary angioedema therapeutics market is segmented by drug class into C1 esterase inhibitors, kallikrein inhibitors, bradykinin receptor antagonists, and others. Among these, C1 esterase inhibitors represent the longest-standing and most widely used class, accounting for a significant portion of the market revenue in 2024. These inhibitors, available in both plasma-derived and recombinant forms, play a crucial role in both acute attack management and long-term prophylaxis. Their efficacy, safety profile, and diverse administration options have made them the mainstay of HAE therapy for decades. However, the market is witnessing a gradual shift towards newer drug classes as patients and physicians seek alternatives with improved convenience and fewer side effects.

Kallikrein inhibitors have emerged as a transformative class within the hereditary angioedema therapeutics market. By targeting plasma kallikrein, these drugs effectively prevent the generation of bradykinin, the primary mediator of HAE attacks. The introduction of subcutaneous and oral kallikrein inhibitors has revolutionized prophylactic therapy, offering patients greater flexibility and ease of use compared to traditional intravenous treatments. Products such as lanadelumab and berotralstat have gained rapid market acceptance, particularly among patients seeking to minimize the frequency and severity of attacks. The strong clinical performance and patient preference for these agents are expected to drive continued growth in this segment.

Bradykinin receptor antagonists constitute another important drug class, specifically indicated for on-demand treatment of acute HAE attacks. These agents, such as icatibant, work by blocking the effects of bradykinin at the receptor level, providing rapid symptom relief. While their use is primarily limited to acute settings, the high efficacy and favorable safety profile of bradykinin receptor antagonists have cemented their role in HAE management. Ongoing research into next-generation antagonists and combination therapies holds promise for further expanding this segment's clinical utility and market share in the coming years.

The "others" category in the drug class segment encompasses emerging therapies and adjunctive treatments that do not fall within the traditional classifications. This includes investigational agents targeting novel pathways, gene therapies, and supportive medications used in conjunction with standard HAE treatments. The pipeline for hereditary angioedema therapeutics is robust, with several candidates in various stages of clinical development. These innovations are expected to diversify the treatment landscape, address unmet medical needs, and contribute to the overall growth and dynamism of the market.

Report Scope

Attributes Details
Report Title Hereditary Angioedema Therapeutic Market Research Report 2033
By Drug Class C1 Esterase Inhibitors, Kallikrein Inhibitors, Bradykinin Receptor Antagonists, Others
By Route Of Administration Oral, Intravenous, Subcutaneous
By Treatment Type On-Demand, Prophylaxis
By Distribution Channel Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
Regions Covered North America, Europe, APAC, Latin America, MEA
Base Year 2024
Historic Data 2018-2023
Forecast Period 2025-2033
Number of Pages 255
Number of Tables & Figures 334
Customization Available Yes, the report can be customized as per your need.

Route of Administration Analysis

The route of administration is a critical factor influencing patient preference, adherence, and overall treatment outcomes in the hereditary angioedema therapeutics market. The market is segmented into oral, intravenous (IV), and subcutaneous (SC) routes. Traditionally, intravenous administration dominated the HAE treatment paradigm, particularly for C1 esterase inhibitors and some acute therapies. IV administration offers rapid onset of action and precise dosing, making it suitable for severe or life-threatening attacks. However, it requires healthcare professional supervision and is associated with inconvenience, risk of infection, and vascular access complications, limiting its appeal for long-term prophylaxis.

The advent of subcutaneous therapies has significantly altered the treatment landscape, providing patients with a more convenient and less invasive option. Subcutaneous administration is now widely adopted for both prophylactic and on-demand therapies, enabling self-administration and reducing the need for frequent hospital visits. Products such as subcutaneous C1 esterase inhibitors and kallikrein inhibitors have demonstrated strong efficacy and safety, leading to rapid uptake and high patient satisfaction. The shift towards subcutaneous formulations is expected to continue, driven by ongoing innovation and patient demand for improved quality of life.

Oral therapies represent the latest frontier in hereditary angioedema treatment, offering unparalleled convenience and accessibility. The approval of oral kallikrein inhibitors has marked a significant milestone, allowing patients to manage their condition with simple daily dosing. Oral treatments eliminate the need for injections, enhance adherence, and are particularly attractive for pediatric and elderly populations. While still a relatively small segment, the oral route is poised for substantial growth as more agents receive regulatory approval and as long-term safety and efficacy data accumulate.

The evolving landscape of administration routes reflects broader trends in patient-centered care and pharmaceutical innovation. Companies are increasingly focused on developing therapies that align with patient lifestyles, minimize treatment burden, and optimize clinical outcomes. The growing diversity of administration options is expected to expand the addressable patient population, improve overall disease management, and drive sustained growth in the hereditary angioedema therapeutics market.

Treatment Type Analysis

The hereditary angioedema therapeutics market is bifurcated by treatment type into on-demand and prophylaxis. On-demand therapies are designed for the acute management of HAE attacks, providing rapid symptom relief and preventing complications. These treatments are essential for patients experiencing unpredictable and potentially life-threatening episodes of angioedema. The on-demand segment is well-established, with a range of effective options including C1 esterase inhibitors and bradykinin receptor antagonists. The availability of fast-acting, self-administered formulations has further enhanced the utility and accessibility of on-demand therapies.

Prophylactic treatments are gaining increasing prominence as the focus shifts towards long-term disease control and prevention. Prophylaxis aims to reduce the frequency, severity, and impact of HAE attacks, thereby improving patient quality of life and reducing healthcare utilization. Advances in prophylactic options, particularly the introduction of subcutaneous and oral therapies, have transformed the management paradigm for many patients. These treatments offer sustained protection, greater convenience, and fewer side effects compared to traditional intravenous regimens. As a result, the prophylaxis segment is expected to outpace on-demand therapies in terms of growth over the forecast period.

The choice between on-demand and prophylactic treatment is highly individualized, depending on factors such as attack frequency, severity, patient preference, and comorbidities. Many patients utilize a combination of both approaches, using prophylaxis for baseline control and on-demand therapies for breakthrough attacks. This integrated strategy underscores the need for a diverse therapeutic toolkit and highlights the importance of personalized medicine in HAE management. The growing emphasis on patient education, shared decision-making, and regular monitoring is expected to further refine treatment selection and optimize outcomes.

Ongoing research and clinical trials are exploring new agents and combination regimens that may blur the traditional lines between on-demand and prophylactic therapy. The development of long-acting, dual-action drugs and gene-based treatments holds promise for further improving disease control and reducing treatment burden. As the therapeutic landscape evolves, the market is likely to see increased segmentation, greater competition, and enhanced value for patients and healthcare systems alike.

Distribution Channel Analysis

The distribution channel segment of the hereditary angioedema therapeutics market includes hospital pharmacies, retail pharmacies, and online pharmacies. Hospital pharmacies have traditionally held the largest share, particularly for intravenous and acute therapies that require professional administration and monitoring. Hospitals are often the first point of care for patients experiencing severe HAE attacks, making them a critical distribution node. The presence of specialized healthcare providers and access to emergency services further reinforce the dominance of hospital pharmacies in the acute treatment segment.

Retail pharmacies have gained traction as the market shifts towards self-administered and maintenance therapies. The increasing availability of subcutaneous and oral treatments has enabled patients to obtain their medications through community-based pharmacies, enhancing convenience and accessibility. Retail pharmacies play a vital role in chronic disease management, offering counseling, support services, and medication adherence programs. As more HAE therapies receive approval for home use, the retail pharmacy segment is expected to capture a growing share of the market.

Online pharmacies represent a rapidly expanding distribution channel, driven by the digitalization of healthcare and changing consumer preferences. The convenience of home delivery, competitive pricing, and discreet service have made online pharmacies an attractive option for many HAE patients, particularly those in remote or underserved areas. Regulatory changes and the COVID-19 pandemic have accelerated the adoption of online pharmacy services, with many pharmaceutical companies partnering with digital platforms to expand their reach. While still a smaller segment compared to traditional channels, online pharmacies are expected to experience robust growth in the coming years.

The evolving distribution landscape reflects broader shifts towards patient empowerment, decentralized care, and digital health. Pharmaceutical companies and distributors are investing in integrated supply chain solutions, telemedicine partnerships, and patient support programs to enhance the overall treatment experience. The increasing diversity of distribution channels is expected to improve medication access, reduce barriers to care, and support the continued expansion of the hereditary angioedema therapeutics market.

Opportunities & Threats

The hereditary angioedema therapeutics market presents a wealth of opportunities for stakeholders across the pharmaceutical value chain. One of the most significant opportunities lies in the development and commercialization of next-generation therapies, including gene editing, RNA-based treatments, and long-acting biologics. These innovations have the potential to address unmet medical needs, improve patient outcomes, and capture premium pricing. Additionally, expanding into emerging markets with rising healthcare investments and increasing disease awareness offers substantial growth potential. Strategic partnerships, licensing agreements, and mergers and acquisitions are expected to accelerate product development, enhance market penetration, and foster innovation across the sector.

Another key opportunity is the integration of digital health solutions and personalized medicine approaches in HAE management. The use of remote monitoring, telemedicine, and mobile health applications can enhance patient engagement, facilitate early intervention, and optimize treatment regimens. Pharmaceutical companies can leverage real-world data and artificial intelligence to identify patient subgroups, predict treatment response, and tailor therapies accordingly. Furthermore, ongoing education and advocacy efforts aimed at healthcare professionals, patients, and policymakers can drive earlier diagnosis, reduce stigma, and increase treatment uptake. These multifaceted opportunities are expected to shape the future trajectory of the hereditary angioedema therapeutics market.

Despite the positive outlook, the market faces several restraining factors that could impede growth. Chief among these is the high cost of HAE therapies, which can pose significant financial barriers for patients and healthcare systems, particularly in low- and middle-income countries. Limited reimbursement, stringent regulatory requirements, and the complexity of biologic drug manufacturing further exacerbate access challenges. Additionally, competition from biosimilars and generic drugs may erode pricing power and profit margins for established players. Addressing these threats will require concerted efforts from industry stakeholders, policymakers, and advocacy groups to ensure equitable access, affordability, and sustainability in the hereditary angioedema therapeutics market.

Regional Outlook

North America continues to lead the global hereditary angioedema therapeutics market, accounting for approximately USD 1.12 billion in revenue in 2024. The region's dominance is underpinned by a combination of high disease awareness, advanced healthcare infrastructure, and rapid adoption of innovative therapies. The United States, in particular, boasts a strong pipeline of HAE drugs, robust clinical research activity, and favorable reimbursement policies. The presence of leading pharmaceutical companies and advocacy organizations further supports market growth. Over the forecast period, North America is expected to maintain its leadership position, supported by a CAGR of 7.9%.

Europe represents the second-largest market, with revenue reaching USD 0.78 billion in 2024. The region benefits from comprehensive healthcare systems, strong regulatory oversight, and increasing patient access to advanced therapies. Key markets such as Germany, the United Kingdom, and France have implemented national HAE treatment guidelines, facilitating early diagnosis and standardized care. The European Union's emphasis on rare disease research and cross-border collaboration has also contributed to market expansion. As biosimilars and generics gain traction, Europe is poised for steady, albeit moderate, growth over the coming years.

The Asia Pacific region is emerging as a high-growth market for hereditary angioedema therapeutics, with revenue estimated at USD 0.28 billion in 2024. Rising healthcare expenditure, increasing disease awareness, and expanding pharmaceutical distribution networks are driving market uptake in countries such as Japan, China, and South Korea. The region's large population base and improving access to genetic testing offer significant untapped potential. However, challenges related to affordability, reimbursement, and healthcare infrastructure persist. Targeted investments in education, diagnostics, and market access strategies are expected to unlock new opportunities and accelerate growth in Asia Pacific.

Hereditary Angioedema Therapeutic Market Statistics

Competitor Outlook

The hereditary angioedema therapeutics market is characterized by intense competition, ongoing innovation, and a dynamic landscape of established and emerging players. Leading pharmaceutical companies are investing heavily in research and development to expand their product portfolios, improve therapeutic efficacy, and differentiate their offerings. The market has witnessed a wave of novel drug approvals, particularly in the kallikrein inhibitor and bradykinin receptor antagonist segments, intensifying competition and driving rapid market evolution. Companies are also pursuing strategic collaborations, licensing agreements, and acquisitions to enhance their capabilities, access new technologies, and accelerate time-to-market for new therapies.

Product differentiation is a key competitive strategy, with companies focusing on improving administration routes, extending dosing intervals, and enhancing safety profiles. The shift towards patient-centric care has prompted the development of self-administered, subcutaneous, and oral therapies, which are rapidly gaining market share. Additionally, firms are investing in patient support programs, digital health solutions, and real-world evidence generation to strengthen their value propositions and foster brand loyalty. The growing emphasis on rare disease advocacy and patient engagement has further intensified competition, as companies seek to build strong relationships with patient communities and healthcare providers.

The entry of biosimilars and generic drugs is reshaping the competitive landscape, particularly in mature markets such as North America and Europe. While these products offer cost advantages and expand patient access, they also exert downward pressure on pricing and margins for originator companies. To maintain their competitive edge, leading players are focusing on lifecycle management strategies, including indication expansions, combination therapies, and next-generation formulations. The rapid pace of scientific and technological advancement is expected to drive ongoing market disruption, creating both challenges and opportunities for industry participants.

Major companies operating in the hereditary angioedema therapeutics market include Takeda Pharmaceutical Company Limited, CSL Behring, Pharming Group N.V., BioCryst Pharmaceuticals, Inc., and Shire (now part of Takeda). Takeda, through its acquisition of Shire, has established a dominant position in the market with a broad portfolio of C1 esterase inhibitors and innovative prophylactic therapies. CSL Behring is recognized for its expertise in plasma-derived therapies and ongoing investment in research and development. Pharming Group N.V. has carved out a niche with its recombinant C1 esterase inhibitor, while BioCryst Pharmaceuticals has been at the forefront of oral kallikrein inhibitor development. These companies are actively pursuing new indications, geographic expansion, and strategic partnerships to sustain growth and maintain their leadership positions.

In addition to these major players, a number of emerging biotechnology firms and specialty pharmaceutical companies are contributing to the vibrancy and competitiveness of the market. Many are focused on developing next-generation therapies, including gene editing and RNA-based treatments, that have the potential to transform the standard of care for hereditary angioedema. The competitive intensity is expected to remain high as new entrants challenge established players, regulatory pathways evolve, and patient expectations continue to rise. Overall, the hereditary angioedema therapeutics market offers a dynamic and rapidly evolving landscape, with significant opportunities for innovation, growth, and value creation.

Key Players

  • Takeda Pharmaceutical Company Limited
  • CSL Behring
  • Pharming Group NV
  • BioCryst Pharmaceuticals, Inc.
  • Shire (now part of Takeda)
  • KalVista Pharmaceuticals, Inc.
  • Ionis Pharmaceuticals, Inc.
  • Attune Pharmaceuticals, Inc.
  • Adverum Biotechnologies, Inc.
  • Pharvaris NV
  • Sanofi
  • Grifols S.A.
  • Octapharma AG
  • Bausch Health Companies Inc.
  • Alnylam Pharmaceuticals, Inc.
  • Intellia Therapeutics, Inc.
  • Regeneron Pharmaceuticals, Inc.
  • Vertex Pharmaceuticals Incorporated
  • Roche Holding AG
  • Amgen Inc.
Hereditary Angioedema Therapeutic Market Overview

Segments

The Hereditary Angioedema Therapeutic market has been segmented on the basis of

Drug Class

  • C1 Esterase Inhibitors
  • Kallikrein Inhibitors
  • Bradykinin Receptor Antagonists
  • Others

Route Of Administration

  • Oral
  • Intravenous
  • Subcutaneous

Treatment Type

  • On-Demand
  • Prophylaxis

Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Competitive Landscape

Major players competing in the global hereditary angioedema therapeutic market are BioCryst Pharmaceuticals Inc; Ionis Pharmaceuticals Inc; Pharming Group N.V; CSL Limited; Shire Plc; Attune Pharmaceuticals Inc; Adverum Biotechnologies Inc; and KalVista Pharmaceuticals Inc. These market players are involved in several business strategies such as mergers, acquisitions partnerships, collaborations, capacity expansion, and product launches to enhance their market shares.

Pharming Group N.V has appointed Inceptua Medicines Access to be their new business & distribution partner for the hereditary angioedema global access program in September 2019. This deal was aimed to help patients across geographies where hereditary angioedema is not available commercially so that every patient has access through ethical mechanisms and regulatory compliant to the products Pharming Group N.V provide.

Hereditary Angioedema Therapeutic Market Key Players

Table Of Content

Chapter 1 Executive Summary
Chapter 2 Assumptions and Acronyms Used
Chapter 3 Research Methodology
Chapter 4 Hereditary Angioedema Therapeutic Market Overview
   4.1 Introduction
      4.1.1 Market Taxonomy
      4.1.2 Market Definition
      4.1.3 Macro-Economic Factors Impacting the Market Growth
   4.2 Hereditary Angioedema Therapeutic Market Dynamics
      4.2.1 Market Drivers
      4.2.2 Market Restraints
      4.2.3 Market Opportunity
   4.3 Hereditary Angioedema Therapeutic Market - Supply Chain Analysis
      4.3.1 List of Key Suppliers
      4.3.2 List of Key Distributors
      4.3.3 List of Key Consumers
   4.4 Key Forces Shaping the Hereditary Angioedema Therapeutic Market
      4.4.1 Bargaining Power of Suppliers
      4.4.2 Bargaining Power of Buyers
      4.4.3 Threat of Substitution
      4.4.4 Threat of New Entrants
      4.4.5 Competitive Rivalry
   4.5 Global Hereditary Angioedema Therapeutic Market Size & Forecast, 2023-2032
      4.5.1 Hereditary Angioedema Therapeutic Market Size and Y-o-Y Growth
      4.5.2 Hereditary Angioedema Therapeutic Market Absolute $ Opportunity

Chapter 5 Global Hereditary Angioedema Therapeutic Market Analysis and Forecast By Drug Class
   5.1 Introduction
      5.1.1 Key Market Trends & Growth Opportunities By Drug Class
      5.1.2 Basis Point Share (BPS) Analysis By Drug Class
      5.1.3 Absolute $ Opportunity Assessment By Drug Class
   5.2 Hereditary Angioedema Therapeutic Market Size Forecast By Drug Class
      5.2.1 C1 Esterase Inhibitors
      5.2.2 Kallikrein Inhibitors
      5.2.3 Bradykinin Receptor Antagonists
      5.2.4 Others
   5.3 Market Attractiveness Analysis By Drug Class

Chapter 6 Global Hereditary Angioedema Therapeutic Market Analysis and Forecast By Route Of Administration
   6.1 Introduction
      6.1.1 Key Market Trends & Growth Opportunities By Route Of Administration
      6.1.2 Basis Point Share (BPS) Analysis By Route Of Administration
      6.1.3 Absolute $ Opportunity Assessment By Route Of Administration
   6.2 Hereditary Angioedema Therapeutic Market Size Forecast By Route Of Administration
      6.2.1 Oral
      6.2.2 Intravenous
      6.2.3 Subcutaneous
   6.3 Market Attractiveness Analysis By Route Of Administration

Chapter 7 Global Hereditary Angioedema Therapeutic Market Analysis and Forecast By Treatment Type
   7.1 Introduction
      7.1.1 Key Market Trends & Growth Opportunities By Treatment Type
      7.1.2 Basis Point Share (BPS) Analysis By Treatment Type
      7.1.3 Absolute $ Opportunity Assessment By Treatment Type
   7.2 Hereditary Angioedema Therapeutic Market Size Forecast By Treatment Type
      7.2.1 On-Demand
      7.2.2 Prophylaxis
   7.3 Market Attractiveness Analysis By Treatment Type

Chapter 8 Global Hereditary Angioedema Therapeutic Market Analysis and Forecast By Distribution Channel
   8.1 Introduction
      8.1.1 Key Market Trends & Growth Opportunities By Distribution Channel
      8.1.2 Basis Point Share (BPS) Analysis By Distribution Channel
      8.1.3 Absolute $ Opportunity Assessment By Distribution Channel
   8.2 Hereditary Angioedema Therapeutic Market Size Forecast By Distribution Channel
      8.2.1 Hospital Pharmacies
      8.2.2 Retail Pharmacies
      8.2.3 Online Pharmacies
   8.3 Market Attractiveness Analysis By Distribution Channel

Chapter 9 Global Hereditary Angioedema Therapeutic Market Analysis and Forecast by Region
   9.1 Introduction
      9.1.1 Key Market Trends & Growth Opportunities By Region
      9.1.2 Basis Point Share (BPS) Analysis By Region
      9.1.3 Absolute $ Opportunity Assessment By Region
   9.2 Hereditary Angioedema Therapeutic Market Size Forecast By Region
      9.2.1 North America
      9.2.2 Europe
      9.2.3 Asia Pacific
      9.2.4 Latin America
      9.2.5 Middle East & Africa (MEA)
   9.3 Market Attractiveness Analysis By Region

Chapter 10 Coronavirus Disease (COVID-19) Impact 
   10.1 Introduction 
   10.2 Current & Future Impact Analysis 
   10.3 Economic Impact Analysis 
   10.4 Government Policies 
   10.5 Investment Scenario

Chapter 11 North America Hereditary Angioedema Therapeutic Analysis and Forecast
   11.1 Introduction
   11.2 North America Hereditary Angioedema Therapeutic Market Size Forecast by Country
      11.2.1 U.S.
      11.2.2 Canada
   11.3 Basis Point Share (BPS) Analysis by Country
   11.4 Absolute $ Opportunity Assessment by Country
   11.5 Market Attractiveness Analysis by Country
   11.6 North America Hereditary Angioedema Therapeutic Market Size Forecast By Drug Class
      11.6.1 C1 Esterase Inhibitors
      11.6.2 Kallikrein Inhibitors
      11.6.3 Bradykinin Receptor Antagonists
      11.6.4 Others
   11.7 Basis Point Share (BPS) Analysis By Drug Class 
   11.8 Absolute $ Opportunity Assessment By Drug Class 
   11.9 Market Attractiveness Analysis By Drug Class
   11.10 North America Hereditary Angioedema Therapeutic Market Size Forecast By Route Of Administration
      11.10.1 Oral
      11.10.2 Intravenous
      11.10.3 Subcutaneous
   11.11 Basis Point Share (BPS) Analysis By Route Of Administration 
   11.12 Absolute $ Opportunity Assessment By Route Of Administration 
   11.13 Market Attractiveness Analysis By Route Of Administration
   11.14 North America Hereditary Angioedema Therapeutic Market Size Forecast By Treatment Type
      11.14.1 On-Demand
      11.14.2 Prophylaxis
   11.15 Basis Point Share (BPS) Analysis By Treatment Type 
   11.16 Absolute $ Opportunity Assessment By Treatment Type 
   11.17 Market Attractiveness Analysis By Treatment Type
   11.18 North America Hereditary Angioedema Therapeutic Market Size Forecast By Distribution Channel
      11.18.1 Hospital Pharmacies
      11.18.2 Retail Pharmacies
      11.18.3 Online Pharmacies
   11.19 Basis Point Share (BPS) Analysis By Distribution Channel 
   11.20 Absolute $ Opportunity Assessment By Distribution Channel 
   11.21 Market Attractiveness Analysis By Distribution Channel

Chapter 12 Europe Hereditary Angioedema Therapeutic Analysis and Forecast
   12.1 Introduction
   12.2 Europe Hereditary Angioedema Therapeutic Market Size Forecast by Country
      12.2.1 Germany
      12.2.2 France
      12.2.3 Italy
      12.2.4 U.K.
      12.2.5 Spain
      12.2.6 Russia
      12.2.7 Rest of Europe
   12.3 Basis Point Share (BPS) Analysis by Country
   12.4 Absolute $ Opportunity Assessment by Country
   12.5 Market Attractiveness Analysis by Country
   12.6 Europe Hereditary Angioedema Therapeutic Market Size Forecast By Drug Class
      12.6.1 C1 Esterase Inhibitors
      12.6.2 Kallikrein Inhibitors
      12.6.3 Bradykinin Receptor Antagonists
      12.6.4 Others
   12.7 Basis Point Share (BPS) Analysis By Drug Class 
   12.8 Absolute $ Opportunity Assessment By Drug Class 
   12.9 Market Attractiveness Analysis By Drug Class
   12.10 Europe Hereditary Angioedema Therapeutic Market Size Forecast By Route Of Administration
      12.10.1 Oral
      12.10.2 Intravenous
      12.10.3 Subcutaneous
   12.11 Basis Point Share (BPS) Analysis By Route Of Administration 
   12.12 Absolute $ Opportunity Assessment By Route Of Administration 
   12.13 Market Attractiveness Analysis By Route Of Administration
   12.14 Europe Hereditary Angioedema Therapeutic Market Size Forecast By Treatment Type
      12.14.1 On-Demand
      12.14.2 Prophylaxis
   12.15 Basis Point Share (BPS) Analysis By Treatment Type 
   12.16 Absolute $ Opportunity Assessment By Treatment Type 
   12.17 Market Attractiveness Analysis By Treatment Type
   12.18 Europe Hereditary Angioedema Therapeutic Market Size Forecast By Distribution Channel
      12.18.1 Hospital Pharmacies
      12.18.2 Retail Pharmacies
      12.18.3 Online Pharmacies
   12.19 Basis Point Share (BPS) Analysis By Distribution Channel 
   12.20 Absolute $ Opportunity Assessment By Distribution Channel 
   12.21 Market Attractiveness Analysis By Distribution Channel

Chapter 13 Asia Pacific Hereditary Angioedema Therapeutic Analysis and Forecast
   13.1 Introduction
   13.2 Asia Pacific Hereditary Angioedema Therapeutic Market Size Forecast by Country
      13.2.1 China
      13.2.2 Japan
      13.2.3 South Korea
      13.2.4 India
      13.2.5 Australia
      13.2.6 South East Asia (SEA)
      13.2.7 Rest of Asia Pacific (APAC)
   13.3 Basis Point Share (BPS) Analysis by Country
   13.4 Absolute $ Opportunity Assessment by Country
   13.5 Market Attractiveness Analysis by Country
   13.6 Asia Pacific Hereditary Angioedema Therapeutic Market Size Forecast By Drug Class
      13.6.1 C1 Esterase Inhibitors
      13.6.2 Kallikrein Inhibitors
      13.6.3 Bradykinin Receptor Antagonists
      13.6.4 Others
   13.7 Basis Point Share (BPS) Analysis By Drug Class 
   13.8 Absolute $ Opportunity Assessment By Drug Class 
   13.9 Market Attractiveness Analysis By Drug Class
   13.10 Asia Pacific Hereditary Angioedema Therapeutic Market Size Forecast By Route Of Administration
      13.10.1 Oral
      13.10.2 Intravenous
      13.10.3 Subcutaneous
   13.11 Basis Point Share (BPS) Analysis By Route Of Administration 
   13.12 Absolute $ Opportunity Assessment By Route Of Administration 
   13.13 Market Attractiveness Analysis By Route Of Administration
   13.14 Asia Pacific Hereditary Angioedema Therapeutic Market Size Forecast By Treatment Type
      13.14.1 On-Demand
      13.14.2 Prophylaxis
   13.15 Basis Point Share (BPS) Analysis By Treatment Type 
   13.16 Absolute $ Opportunity Assessment By Treatment Type 
   13.17 Market Attractiveness Analysis By Treatment Type
   13.18 Asia Pacific Hereditary Angioedema Therapeutic Market Size Forecast By Distribution Channel
      13.18.1 Hospital Pharmacies
      13.18.2 Retail Pharmacies
      13.18.3 Online Pharmacies
   13.19 Basis Point Share (BPS) Analysis By Distribution Channel 
   13.20 Absolute $ Opportunity Assessment By Distribution Channel 
   13.21 Market Attractiveness Analysis By Distribution Channel

Chapter 14 Latin America Hereditary Angioedema Therapeutic Analysis and Forecast
   14.1 Introduction
   14.2 Latin America Hereditary Angioedema Therapeutic Market Size Forecast by Country
      14.2.1 Brazil
      14.2.2 Mexico
      14.2.3 Rest of Latin America (LATAM)
   14.3 Basis Point Share (BPS) Analysis by Country
   14.4 Absolute $ Opportunity Assessment by Country
   14.5 Market Attractiveness Analysis by Country
   14.6 Latin America Hereditary Angioedema Therapeutic Market Size Forecast By Drug Class
      14.6.1 C1 Esterase Inhibitors
      14.6.2 Kallikrein Inhibitors
      14.6.3 Bradykinin Receptor Antagonists
      14.6.4 Others
   14.7 Basis Point Share (BPS) Analysis By Drug Class 
   14.8 Absolute $ Opportunity Assessment By Drug Class 
   14.9 Market Attractiveness Analysis By Drug Class
   14.10 Latin America Hereditary Angioedema Therapeutic Market Size Forecast By Route Of Administration
      14.10.1 Oral
      14.10.2 Intravenous
      14.10.3 Subcutaneous
   14.11 Basis Point Share (BPS) Analysis By Route Of Administration 
   14.12 Absolute $ Opportunity Assessment By Route Of Administration 
   14.13 Market Attractiveness Analysis By Route Of Administration
   14.14 Latin America Hereditary Angioedema Therapeutic Market Size Forecast By Treatment Type
      14.14.1 On-Demand
      14.14.2 Prophylaxis
   14.15 Basis Point Share (BPS) Analysis By Treatment Type 
   14.16 Absolute $ Opportunity Assessment By Treatment Type 
   14.17 Market Attractiveness Analysis By Treatment Type
   14.18 Latin America Hereditary Angioedema Therapeutic Market Size Forecast By Distribution Channel
      14.18.1 Hospital Pharmacies
      14.18.2 Retail Pharmacies
      14.18.3 Online Pharmacies
   14.19 Basis Point Share (BPS) Analysis By Distribution Channel 
   14.20 Absolute $ Opportunity Assessment By Distribution Channel 
   14.21 Market Attractiveness Analysis By Distribution Channel

Chapter 15 Middle East & Africa (MEA) Hereditary Angioedema Therapeutic Analysis and Forecast
   15.1 Introduction
   15.2 Middle East & Africa (MEA) Hereditary Angioedema Therapeutic Market Size Forecast by Country
      15.2.1 Saudi Arabia
      15.2.2 South Africa
      15.2.3 UAE
      15.2.4 Rest of Middle East & Africa (MEA)
   15.3 Basis Point Share (BPS) Analysis by Country
   15.4 Absolute $ Opportunity Assessment by Country
   15.5 Market Attractiveness Analysis by Country
   15.6 Middle East & Africa (MEA) Hereditary Angioedema Therapeutic Market Size Forecast By Drug Class
      15.6.1 C1 Esterase Inhibitors
      15.6.2 Kallikrein Inhibitors
      15.6.3 Bradykinin Receptor Antagonists
      15.6.4 Others
   15.7 Basis Point Share (BPS) Analysis By Drug Class 
   15.8 Absolute $ Opportunity Assessment By Drug Class 
   15.9 Market Attractiveness Analysis By Drug Class
   15.10 Middle East & Africa (MEA) Hereditary Angioedema Therapeutic Market Size Forecast By Route Of Administration
      15.10.1 Oral
      15.10.2 Intravenous
      15.10.3 Subcutaneous
   15.11 Basis Point Share (BPS) Analysis By Route Of Administration 
   15.12 Absolute $ Opportunity Assessment By Route Of Administration 
   15.13 Market Attractiveness Analysis By Route Of Administration
   15.14 Middle East & Africa (MEA) Hereditary Angioedema Therapeutic Market Size Forecast By Treatment Type
      15.14.1 On-Demand
      15.14.2 Prophylaxis
   15.15 Basis Point Share (BPS) Analysis By Treatment Type 
   15.16 Absolute $ Opportunity Assessment By Treatment Type 
   15.17 Market Attractiveness Analysis By Treatment Type
   15.18 Middle East & Africa (MEA) Hereditary Angioedema Therapeutic Market Size Forecast By Distribution Channel
      15.18.1 Hospital Pharmacies
      15.18.2 Retail Pharmacies
      15.18.3 Online Pharmacies
   15.19 Basis Point Share (BPS) Analysis By Distribution Channel 
   15.20 Absolute $ Opportunity Assessment By Distribution Channel 
   15.21 Market Attractiveness Analysis By Distribution Channel

Chapter 16 Competition Landscape 
   16.1 Hereditary Angioedema Therapeutic Market: Competitive Dashboard
   16.2 Global Hereditary Angioedema Therapeutic Market: Market Share Analysis, 2023
   16.3 Company Profiles (Details – Overview, Financials, Developments, Strategy) 
      16.3.1 Takeda Pharmaceutical Company Limited
CSL Behring
Pharming Group NV
BioCryst Pharmaceuticals, Inc.
Shire (now part of Takeda)
KalVista Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc.
Attune Pharmaceuticals, Inc.
Adverum Biotechnologies, Inc.
Pharvaris NV
Sanofi
Grifols S.A.
Octapharma AG
Bausch Health Companies Inc.
Alnylam Pharmaceuticals, Inc.
Intellia Therapeutics, Inc.
Regeneron Pharmaceuticals, Inc.
Vertex Pharmaceuticals Incorporated
Roche Holding AG
Amgen Inc.

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