Segments - Extrapyramidal Treatment Market By Symptoms Type (Pseudo-parkinsonism, Dystonia Symptoms, Akathisia (Restlessness), Tardive Dyskinesia), By Drug Type (Atypical Antipsychotics (Aripiprazole, Clozapine, Quetiapine and Others), Anticholinergic Drug (Benztropine, Trihexyphenidyl, Others), Atypical Antidepressant, Antihistamine, Benzodiazepine Drugs (Lorazepam, Clonazepam, Others), Others), By End-user (Hospitals, Clinics, Research & Academic Center), By Sales Channel (Online Pharmacy and Offline Pharmacy (Hospital Pharmacy, Retail Pharmacy)), and Region (North America, Asia Pacific, Europe, Latin America, and the Middle East & Africa) - Global Industry Analysis, Growth, Share, Size, Trends and, Forecast 2024 – 2032
The global extrapyramidal treatment market was estimated at USD 1,209.0 Million in 2023 and is anticipated to reach USD 1,703.7 Million by 2032, expanding at a CAGR of 3.9% during the forecast period.
Extrapyramidal symptoms (EPS) are a group of movement disorders that result from dysfunction in the extrapyramidal system, a neural network in the brain responsible for controlling voluntary movements. These symptoms arise as side effects of certain medications, particularly antipsychotic drugs, or as manifestations of underlying neurological conditions. EPS refers to the management and care provided to individuals with movement disorders that involve the extrapyramidal system, a neural network in the brain responsible for controlling voluntary movements. These movement disorders include conditions such as parkinson's disease, dystonia, tremors, and chorea. The pharmaceutical industry is focused on developing antipsychotic drugs that have a lower risk of EPS.
The research report finds that the COVID-19 pandemic has had various effects on the global extrapyramidal treatment market, which primarily deals with medications and therapies for conditions affecting the extrapyramidal system, such as parkinson's disease, dystonia, and other movement disorders. The clinical trials investigating new therapies for movement disorders may have been delayed or interrupted due to COVID-19-related restrictions. This postpones the introduction of novel treatments to the market and impact the pipeline of potential extrapyramidal treatments in development.
AI-powered drug discovery platforms accelerate the identification and optimization of novel therapeutic compounds for extrapyramidal disorders. By analyzing chemical structures, pharmacological properties, and biological activity data, AI algorithms predict the likelihood of a candidate molecule to modulate specific targets implicated in movement disorders. This accelerates the drug discovery process and expand the pipeline of potential treatments. Artificial Intelligence (AI) in Drug Discovery, to evaluate huge amounts of data to find new therapeutic targets and accelerate the drug development process. AI technologies enable the identification of molecular targets and pathways underlying extrapyramidal disorders, paving the way for the development of targeted therapies. By analyzing genetic, proteomic, and transcriptomic data, AI identify potential drug targets and biomarkers for patient stratification, facilitating the development of precision medicine approaches in the treatment of movement disorders.
Higher healthcare expenditure often correlates with better access to healthcare services, including specialized treatment for movement disorders. Healthcare expenditure contributes to funding for research and development initiatives aimed at discovering new treatments and improving existing therapies for movement disorders. Pharmaceutical companies and research institutions rely on healthcare funding to conduct clinical trials, develop innovative drugs, and advance medical technology in this field. Healthcare expenditure supports the development and maintenance of healthcare infrastructure, including hospitals, clinics, and rehabilitation centers equipped to diagnose and treat movement disorders. Adequate healthcare infrastructure is essential for providing timely and effective care to patients with extrapyramidal disorders.
According to American Medical Association, in 2022, health-care spending in the United States rose by 4.1% to $4.4 trillion, or $13,493 per person. This growth rate is comparable to the pre-pandemic rate (4.1% in 2019). Although government spending to manage the pandemic led to significant increases in NHE, these expenditures fell significantly in 2021, while medical goods and services usage rebounded. By 2022, top-level health spending patterns will be more similar to those observed prior to the pandemic.
The rising prevalence of movement disorders, particularly among aging populations, is a significant driver of the extrapyramidal treatment market. Factors such as demographic aging, lifestyle changes, and improved diagnosis contribute to the growing patient population in need of treatment for conditions like Parkinson's disease. For instance, according to WHO 8.5 million individuals having Parkinson disease (PD) in 2019. The prevalence of PD has doubled in the past 25 years.
Adverse effects such as motor fluctuations, dyskinesias, cognitive impairments, and psychiatric symptoms affects patient tolerability and adherence to treatment regimens. Patients may discontinue or modify their medications due to intolerable side effects, leading to suboptimal treatment outcomes and disease progression. Concerns about adverse effects may influence physician prescribing patterns and treatment decisions. Healthcare providers may be cautious when prescribing medications with known safety risks, particularly in elderly or medically complex patients, leading to underutilization of potentially effective therapies.
Targeted therapies and precision medicine enable healthcare providers to tailor treatment strategies to the specific molecular and genetic characteristics of individual patients. By identifying biomarkers, genetic variants, and disease subtypes associated with extrapyramidal disorders, precision medicine offers opportunities to optimize treatment efficacy, minimize adverse effects, and improve patient outcomes. Precision medicine approaches facilitate the development of neuroprotective and disease-modifying treatments that slow or halt the progression of extrapyramidal disorders. Therapeutic strategies targeting alpha-synuclein aggregation, mitochondrial dysfunction, neuroinflammation, and oxidative stress offer opportunities to intervene in disease pathogenesis and preserve neuronal function.
The report on the global extrapyramidal treatment market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes |
Details |
Report Title |
Extrapyramidal Treatment Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast |
Base Year |
2023 |
Historic Data |
2017–2022 |
Forecast Period |
2024–2032 |
Segmentation |
By Symptoms Type (Pseudo-parkinsonism, Dystonia Symptom, Akathisia (Restlessness), and Tardive Dyskinesia), By Drug Type (Atypical Antipsychotics (Aripiprazole, Clozapine, Quetiapine and Others), Anticholinergic Drug (Benztropine, Trihexyphenidyl, Others), Atypical Antidepressant, Antihistamine, Benzodiazepine Drugs (Lorazepam, Clonazepam, Others), and Others), By End-user (Hospitals, Clinics, and Research & Academic Center), By Sales Channel (Online Pharmacy and Offline Pharmacy (Hospital Pharmacy, Retail Pharmacy)) |
Regional Scope |
Asia Pacific, North America, Latin America, Europe, and Middle East & Africa |
Report Coverage |
Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, and Trends, and Revenue Forecast |
Key Players Covered |
GlaxoSmithKline PLC; Sanofi; AstraZeneca; Eli Lilly and Company; Pfizer Inc.; Johnson and Johnson; Otsuka Pharmaceutical Co, Ltd.; AbbVie Inc.; Teva Pharmaceutical Industries Ltd.; Bristol Myers Squibb; and others. |
Based on symptoms type, the global extrapyramidal treatment market is segmented into pseudo-parkinsonism, dystonia symptom, akathisia (restlessness), tardive dyskinesia. The Pseudo-parkinsonism segment is anticipated to hold XX% market share in 2023, due to increasing prevalence and use of antipsychotic medications in various clinical settings, including psychiatry, neurology, and primary care. As a result, there is an increased demand for treatment options to manage the motor symptoms associated with pseudo-parkinsonism.
On the basis of drug type, the global extrapyramidal treatment market is classified as atypical antipsychotics (aripiprazole, clozapine, quetiapine and others), anticholinergic drug (benztropine, trihexyphenidyl, others), atypical antidepressant, antihistamine, benzodiazepine drugs (lorazepam, clonazepam, others), others. The anticholinergic drug segment is anticipated to hold 32.4% share of the market in 2023, due to increasing anticholinergic drug to manage neuropsychiatric symptoms commonly associated with neurological conditions such as Parkinson's disease, Huntington's disease, and multiple system atrophy. These medications help to regain the balance of chemical messengers in the brain that are disrupted by antipsychotic medications. Examples of anticholinergics include benztropine (Cogentin) and trihexyphenidyl (Artane).
In terms of end-user, the extrapyramidal treatment market is categorized as hospitals, clinics, research & academic center. The hospitals segment is expected to hold a market share of 45.5% in 2023, as hospitals, particularly those with specialized neurology departments or movement disorder centers, play a key role in the diagnosis and management of extrapyramidal disorders. These facilities offer access to neurologists, movement disorder specialists, neurosurgeons, rehabilitation therapists, and other healthcare professionals with expertise in treating movement disorders.
In terms of sales channel, the extrapyramidal treatment market is categorized as online pharmacy, offline pharmacy (hospital pharmacy, retail pharmacy). The online pharmacy segment is expected to hold a market share of XX% in 2023, as online pharmacies provide individuals with convenient access to a wide range of extrapyramidal medications, including antipsychotics, antidepressants, anticholinergics, and other pharmacological agents used in the management of movement disorders. Patients order prescriptions online and have medications delivered directly to their doorstep, eliminating the need for in-person visits to traditional brick-and-mortar pharmacies.
On the basis of region, the global extrapyramidal treatment market is divided into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa (MEA).
The market in North America is projected to expand at a CAGR of 7.2% during the forecast period, primarily due to high disease burden in North America, particularly the United States and Canada, has a substantial burden of extrapyramidal disorders such as Parkinson's disease, essential tremor, dystonia, and Huntington's disease.
Europe held XX% share of the market in 2023, and the market in the region is expected to expand at a CAGR of XX% during the forecast period, as Europe is a hub of research and innovation in the field of extrapyramidal treatment, with numerous academic institutions, research centers, and pharmaceutical companies conducting clinical trials, translational research, and technology development initiatives. Collaborative research networks and funding programs support advancements in treatment options and personalized medicine approaches.
In-depth Analysis of the Global Extrapyramidal Treatment Market
Historical, Current, and Projected Market Size in terms of Value
Potential & Niche Segments and Regions Exhibiting Promising Growth Covered
Industry Drivers, Restraints, and Opportunities Covered in the Study
Recent Industry Trends and Developments
Competitive Landscape & Strategies of Key Players
Neutral Perspective on Global Extrapyramidal Treatment Market performance
Manufacturers operating in the global extrapyramidal treatment market include GlaxoSmithKline PLC, Sanofi, AstraZeneca, Eli Lilly and Company, Pfizer Inc., Johnson and Johnson, Otsuka Pharmaceutical Co, Ltd., AbbVie Inc., Teva Pharmaceutical Industries Ltd., Bristol Myers Squibb.
The Increased awareness and education initiatives raise public and healthcare provider awareness is expected to have a significant impact on the global extrapyramidal treatment market. The Increased awareness and education initiatives raise public and healthcare provider awareness about movement disorders, their symptoms, and available treatment options. Patient advocacy groups, medical societies, and healthcare organizations drive initiatives to improve diagnosis, treatment, and support services for affected individuals.
In June 2021, the pharmaceutical company, Alkermes plc received U.S. Food and Drug Administration (FDA) approval for LYBALVI (olanzapine and samidorphan) for the treatment of adults with schizophrenia.
The base year considered for the global extrapyramidal treatment market report is 2023. The complete analysis period is 2022 to 2032, wherein, 2017, and 2022 are the historic years, and the forecast is provided from 2024 to 2032.
In addition to market size (in USD Million) company market share (in % for the base year 2023) is available in the report. Moreover, additional data analysis can be provided on request.
During the pandemic, healthcare systems faced significant disruptions, with resources diverted to managing COVID-19 patients. Non-urgent medical appointments, including those for extrapyramidal disorders, were postponed or canceled, leading to delays in diagnosis, treatment, and management. Individuals with movement disorders faced challenges in accessing healthcare services due to lockdowns, travel restrictions, and reduced availability of in-person consultations. Telemedicine emerged as a valuable alternative for remote consultations, medication management, and monitoring of symptoms, helping to bridge gaps in care.
GlaxoSmithKline PLC, Sanofi, AstraZeneca, Eli Lilly and Company, Pfizer Inc.
Rising GDPs of emerging economies, healthcare expenditure, R&D activities, government regulation are expected to act as macroeconomic factors for the market.
Hospitals, clinics and research & academic center are the end-user of extrapyramidal treatment market.
According to this Growth Market Reports report, the extrapyramidal treatment market is likely to register a CAGR of 3.9% during the forecast period 2023-2032, with an anticipated valuation of USD 1,703.7 million by the end of 2032.
Increasing prevalence of movement disorders, increasing awareness and early diagnosis, expanding therapeutic pipeline.
Factors such as competitive strength and market positioning are key areas considered while selecting top companies to be profiled.
Additional company profiles can be provided on request. For a discussion related to the above findings, click Speak to Analyst