Segments - Erosive Esophagitis Market by Drug Class (Proton Pump Inhibitors, Potassium-Competitive Acid Blockers, Histamine-2 Receptor Antagonists and Others), by Age Group (Children and Adults), by End Use (Hospitals, Clinics, and Others), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), and by Region (North America, Asia Pacific, Europe, Latin America, and the Middle East & Africa) - Global Industry Analysis, Growth, Share, Size, Trends and, Forecast 2023 – 2031
The global erosive esophagitis market was USD 4,767.66 Million in 2022 and is anticipated to reach USD 21,157.27 Million by 2031, expanding at a CAGR of 18.4% during the forecast period.
Erosive esophagitis is a type of esophagitis caused by inflammation and damage to the lining of the esophagus. It is caused by the backflow of stomach acid into the esophagus, a condition known as gastroesophageal reflux disease (GERD). Symptoms of erosive esophagitis include chest pain, difficulty in swallowing, and odynophagia. The treatment for esophagitis depends on the underlying cause and how badly the tissue lining the esophagus is damaged.
For instance, according to report published in National Library of Medicine, in western countries, the prevalence of erosive esophagitis is approximately 10% to 20%, while in that in Asian countries is approximately 5%.
The research report finds that the COVID-19 pandemic has had significant impact on the global erosive esophagitis market. With many companies suspending their manufacturing and transportation operations in different locations due to lockdowns and post-pandemic restrictions, the global erosive esophagitis market had significantly affected. However, the exclusion of healthcare related services from stringent pandemic regulations in many parts of the world helped several companies to survive during the COVID-19 pandemic period.
Artificial intelligence has a significant impact on global erosive esophagitis market. AI is use in the field of esophageal diseases in the development of an AI-assisted diagnosis for cytological detection of esophageal squamous lesions. This technology is able to help in the early detection and diagnosis of esophageal diseases, including erosive esophagitis.
AI is able to analyze large amounts of data and identify patterns that may not be apparent to human analysts. This is expected to lead to the discovery of new treatments or therapies for erosive esophagitis, and the development of effective or curative therapies.
The healthcare industry is expected to grow at a rapid pace in the coming years due to growing population and addition of new hospitals, clinics, and health centers. The demand for healthcare services globally has increased rapidly in the recent years, due to the increasing prevalence of chronic diseases and non-communicable diseases. The expansion of the healthcare industry plays a substantial role in shaping the landscape of erosive esophagitis, impacting its epidemiology, management, and market dynamics.
The rising prevalence of GERD is affecting the growth of erosive esophagitis in several ways. It is the part of GERD spectrum that leads to esophageal adenocarcinoma if not treated in the early stages. Conditions that increase the risk of GERD include obesity, smoking, pregnancy, hiatal hernia, delayed stomach emptying, eating certain trigger foods, and eating large meals or eating late at night. Approximately 30% of GERD cases are able to further progress into erosive esophagitis. Apart from the compromise on quality of life, prolonged esophagitis further encourages esophageal epithelium metaplasia and progression of adenocarcinoma.
For instance, a report published in National Library of Medicine states that the prevalence of GERD is 18.1%–27.8% in North America, 8.8%–25.9% in Europe, and 2.5%–7.8% in East Asia. This prevalence of GERD cases is directly increasing the demand for erosive esophagitis medications in the market.
The treatment for erosive esophagitis includes the use of several medications including esomeprazole and omeprazole. The medications used in the treatment are tend to develop various unintended effects including serious skin reactions and hypomagnesemia. It can lead to allergic reactions, severe diarrhea, and unusual tiredness or weakness. In severe progression of side effects, it leads to complications such as severe ulceration, gastrointestinal bleeding, and esophageal strictures. Therefore, the high-risk involvement in the treatment acts as a restraint for global erosive esophagitis market.
Increasing innovations in drug delivery systems and the development of efficient and safe drugs are expected to creative many lucrative opportunities in the erosive esophagitis market during the forecast period. For instance,
Phathom Pharmaceuticals erosive esophagitis drug vonoprazan is a potassium-competitive acid blocker (P-CAB) under examination to relieve heartburn and heal all severities of erosive esophagitis. In a phase 3 PHALCON-EE trial, vonoprazan met the main goal of the trial in the healing phase, proving non-inferiority to Prevacid, a common over-the-counter medication for reducing acid and treating the symptoms of stomach and esophagus.
The report on the global erosive esophagitis market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes |
Details |
Report Title |
Erosive Esophagitis Market– Global Industry Analysis, Size, Share, Growth, Trends, and Forecast |
Base Year |
2022 |
Historic Data |
2016–2021 |
Forecast Period |
2023–2031 |
Segmentation |
Drug Class (Proton Pump Inhibitors, Potassium-Competitive Acid Blockers, Histamine-2 Receptor Antagonists and Others), Age Group (Children and Adults), End-use (Hospitals, Clinics, and Others), and Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies) |
Regional Scope |
Asia Pacific, North America, Latin America, Europe, and Middle East & Africa |
Report Coverage |
Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, and Trends, and Revenue Forecast |
Key Players Covered |
Camber Pharmaceuticals, Inc, DM Pharma, Haleon group of companies, HK inno.N Corporation, McNeil Consumer Pharmaceuticals Co, Pfizer Inc, Phathom Pharmaceuticals, Procter & Gamble, Soigner Pharma, Takeda Pharmaceuticals U.S.A., Inc, Teva Pharmaceuticals USA, Inc. |
Based on drug class, the global erosive esophagitis market is segmented into proton pump inhibitors, potassium-competitive acid blockers, histamine-2 receptor antagonists, and others. The proton pump inhibitors segment is expected to hold a substantial share of the market during the forecast period, as it is an effective treatment for erosive esophagitis.
PPIs work by irreversibly blocking the H+/K+ ATPase enzyme or the gastric proton pump, which is found within the parietal cells of the stomach and is the final step of acid production. By undergoing acid-activation to sulfenamides, PPIs covalently bond to cysteine residues on the luminal surface of the proton pump, blocking ion transport and acid secretion. This effect enables healing of peptic ulcers, gastroesophageal reflux disease (GERD), Barrett’s esophagus, and Zollinger-Ellison syndrome.
Based on age group, the global erosive esophagitis market is classified as children and adults. The adult’s segment is projected to account for a significant share of the market during the forecast period, due to the rise in prevalence rate of the erosive esophagitis among adults. One of the primary causes of erosive esophagitis is chronic acid reflux or GERD, which is prevalent in adults, affecting at least 20% of the population.
On the basis of end-use, the global erosive esophagitis market is segmented into hospitals, clinics, and others. The hospital segment is projected to account for a significant share during the forecast period, as hospitals provide a wide range of medical services to patients, including treatment for erosive esophagitis. Hospitals have a wide range of specialized medical equipment, expertise, and resources as compared to other institutions making them equipped to handle the intensive care often required for erosive esophagitis.
In terms of distribution channel, the global erosive esophagitis market is segmented into hospital pharmacies, retail pharmacies, and online pharmacies. The hospital pharmacies segment is projected to expand at a significant CAGR during the forecast period. Hospital pharmacies are expected to register increased sales in the coming years, owing to its wide range of products, specialized expertise, integration with healthcare facilities, regulatory compliance, and comprehensive patient support and education.
On the basis of region, the global erosive esophagitis market is divided into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa (MEA).
The erosive esophagitis market in North America accounted for a significant share of the market in 2022 owing to the rising number of patients with GERD. Over the last decade, there has been a significant increase in the proportion of young patients with GERD in North America, especially those within the age range of 30–39 years. For instance,
A report published in BioMed Central states that the prevalence of GERD in North America is estimated to be between 18.1% and 27.8%.
The erosive esophagitis market in Asia Pacific is projected to expand at a CAGR during the forecast period, owing to the growing awareness and diagnosis of GERD in developing nations. Moreover, the expansion of the healthcare sector in Asia Pacific and the growing research prospects are boosting the adoption of treatments for erosive esophagitis.
In-depth Analysis of the Global Erosive Esophagitis Market
Historical, Current, and Projected Market Size in terms of Value
Potential & Niche Segments and Regions Exhibiting Promising Growth Covered
Industry Drivers, Restraints, and Opportunities Covered in the Study
Recent Industry Trends and Developments
Competitive Landscape & Strategies of Key Players
Neutral Perspective on Global Erosive Esophagitis Market performance
Manufacturers operating in the global erosive esophagitis market include Camber Pharmaceuticals, Inc, DM Pharma, Haleon group of companies, HK inno.N Corporation, McNeil Consumer Pharmaceuticals Co, Pfizer Inc, Phathom Pharmaceuticals, Procter & Gamble, Soigner Pharma, Takeda Pharmaceuticals U.S.A., Inc., and Teva Pharmaceuticals USA, Inc.
Market players are pursuing key strategies such as acquisitions, collaborations, and geographic expansion where a potential opportunity arises for the erosive esophagitis market.
In November 2023, Camber Pharmaceuticals, Inc. announced the addition of Famotidine Powder for oral suspension in its current portfolio. Famotidine is an antihistamine used to treat and prevent ulcers in the stomach and intestines and other conditions caused by excess stomach acid.
In June 2022, Glenmark Pharmaceuticals Ltd acquired the approved generic versions of several over-the-counter drugs from Wockhardt Ltd in the United States. The acquisition by the company's fully owned subsidiary Glenmark Pharmaceuticals Inc, USA includes the approved abbreviated new drug applications (ANDAs) for famotidine tablets (10 mg and 20 mg) used to treat and prevent ulcers in the stomach and intestine, including heartburn, acid reflux, indigestion, and many other symptoms.
Additional company profiles can be provided on request. For a discussion related to the above findings, click Speak to Analyst
Factors such as competitive strength and market positioning are key areas considered while selecting top companies to be profiled.
Rising Prevalence of GERD, Growing Awareness Regarding Erosive Esophagitis Diagnosis and Treatment, and Increasing Funds Provided by Government for Medical Research on Drugs are the factors driving the growth of the Erosive Esophagitis Market.
According to this Growth Market Reports report, the Erosive Esophagitis Market is likely to register a CAGR of 18.4% during the forecast period 2022-2031, with an anticipated valuation of USD 21,157.27 Million by the end of 2031.
Adults and Children are the end-user of Erosive Esophagitis.
Growing Population, Government Healthcare Policies, and Healthcare Industry Growth are expected to act as macroeconomic factors for the market.
Major manufacturers include Camber Pharmaceuticals, Inc, DM Pharma, Haleon group of companies, HK inno.N Corporation, McNeil Consumer Pharmaceuticals Co, Pfizer Inc, Phathom Pharmaceuticals, Procter & Gamble, Soigner Pharma, Takeda Pharmaceuticals U.S.A., Inc, Teva Pharmaceuticals USA, Inc., and others.
The outbreak of coronavirus disease in 2019 (COVID-19) hampered global economy, created global interdependence, and challenged governments of many nations. The long-term effects of the pandemic are expected to hamper various industries during the forecast period, especially across Eastern Europe, the European Union, Eastern & Central Asia, and the US.
In addition to market size (in US$ Million) Company Market Share (in % for the base year 2022) is available in the report. Moreover, additional data analysis can be provided on request.
The base year considered for the Global Erosive Esophagitis Market report is 2022. The complete analysis period is 2021 to 2031, wherein, 2016, and 2021 are the historic years, and the forecast is provided from 2023 to 2031.