Report Description
CRISPR & Cas Genes Market Outlook 2031
The global CRISPR & cas genes market size was valued at USD 2.09 Billion in 2022 and is expected to surpass USD 7.75 Billion by 2031, expanding at a CAGR of 15.67% during the forecast period, 2023–2031. The growth of the market is attributed to its increased use in several domains of biotechnology, such as epigenetics and medicine, human germline editing, and a tool for qualitative and quantitative plant genome editing.
CRISPR-cas techniques are powerful nucleic acid-targeting technologies that are simple to program. Its applications span from research and drug discovery to precision breeding of plants and animals and industrial microbial engineering.
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a gene editing method. CRISPR-cas is a significant breakthrough in biological science. It offers the potential to cure rare diseases in a variety of contexts. Researchers use this technology to change elements of the genome by adding, changing, or removing sections of the DNA sequence.
Many patients undergoing CRISPR-Cas gene therapy are being monitored and are waiting for FDA approval. The CRISPR-Cas system is a prokaryotic immune system that enables acquired immunity by conferring resistance to exogenous genetic elements.
It is faster, more efficient, and more precise than previous DNA modification techniques, and it has a wide range of possible uses. Crop breeding, biotechnology and pharmaceutical businesses, microbial engineering, and genome engineering all use this method.
CRISPR & Cas Genes Market Trends, Drivers, Restraints, and Opportunities
Major Drivers
- Increasing number of strategic collaborations between market players is projected to boost the market during the forecast period.
- Rising funding and investments in gene editing technologies is expected to promote the growth of the market during the forecast period.
- Development of CRISPR technologies is anticipated to boost the market.
- Increasing incidence of genetic disorders is expected to fuel the market during the forecast period.
Existing Restraints
- Rising ethical and safety issues regarding CRISPR technologies is expected to hinder the market growth during the forecast period.
- Availability of alternatives of CRISPR & cas genes is anticipated to hamper the market expansion in the coming years.
Emerging Opportunities
Increasing number of clinical trials using CRISPR technology to develop treatments for diseases such as thalassemia, sickle cell disease, myeloma, solid tumors, and hematologic malignancies, diabetes, and others, is expected to create opportunities for the market players.
Scope of CRISPR & Cas Genes Market Report
The report on the global CRISPR & cas genes market includes an assessment of the market, trends, segments, and regional markets. Overview and dynamics have also been included in the report.
Attributes
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Details
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Report Title
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CRISPR & Cas Genes Market - Global Industry Analysis, Growth, Share, Size, Trends, and Forecast
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Base Year
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2022
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Historic Data
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2016–2021
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Forecast Period
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2023–2031
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Segmentation
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Products (Vector-based Cas and DNA-free Cas), Applications (Genome Engineering, Disease Models, Functional Genomics, and Others), End-users (Biotechnology & Pharmaceutical Companies, Academics & Government Research Institutes, and Contract Research Organizations)
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Regional Scope
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Asia Pacific, North America, Latin America, Europe, and Middle East & Africa
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Report Coverage
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Company Share, Market Analysis and Size, Competitive Landscape, Growth Factors, and Trends, and Revenue Forecast
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Key Players Covered in the Report
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OriGene Technologies, Inc., Thermo Fisher Scientific, Takara Bio Inc, Horizon Discovery Ltd., Addgene, Merck KGaA, Caribou Biosciences, Inc., CRISPR THERAPEUTICS, Editas Medicine, and Mirus Bio LLC
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CRISPR & Cas Genes Market Segment Insights
Product Segment Analysis
Based on products, the CRISPR & cas genes market is divided into vector-based cas and DNA-free cas. The vector-based cas segment is anticipated to dominate the market during the forecast period. Medical researchers focusing on Cas9 enrichment benefit from vector-based cas systems. A promoter is usually included in the vector-based cas, allowing stable cell lines to be created.
Application Segment Analysis
In terms of applications, the global CRISPR & cas genes market is segregated into genome engineering, disease models, functional genomics, and others. The genome engineering segment is anticipated to dominate the market during the forecast period.
To generate genomic engineering, natural genomic sequences are coupled with a synthetic assembly of entire chromosomal DNA. The method allows for the addition, modification, or removal of genetic material from specified genomic sites. For the foreseeable future, extensive biomedical research is expected to propel the market.
End-users Segment Analysis
On the basis of end users, the global CRISPR & cas genes market is segregated into biotechnology & pharmaceutical companies, academics & government research institutes, and contract research organizations. The biotechnology and pharmaceutical companies segment is anticipated to dominate the market during the forecast period.
The segment is being fueled by the rising adoption of CRISPR technology by prominent biotechnology and pharmaceutical companies. Companies are increasingly turning to CRISPR-Cas9 to generate biological models for human diseases in less time and to speed up the discovery and validation of new therapeutic targets.
Regional Outlook
On the basis of regions, the global CRISPR & cas genes market is classified as Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. North America is expected to dominate the market at a high CAGR during the forecast period.
Factors such as the existence of significant companies, increased spending in biotechnology and genomics programs, and developed healthcare infrastructure are some of the primary factors responsible for the large share of the market in North America.

Segments
Products
- Vector-based Cas
- DNA-free Cas
Applications
- Genome Engineering
- Disease Models
- Functional Genomics
- Others
End-users
- Biotechnology & Pharmaceutical Companies
- Academics & Government Research Institutes
- Contract Research Organizations
Regions
- Asia Pacific
- North America
- Europe, Latin America
- Middle East & Africa
Key Players
- OriGene Technologies, Inc.
- Thermo Fisher Scientific
- Takara Bio Inc
- Horizon Discovery Ltd.
- Addgene
- Merck KGaA
- Caribou Biosciences, Inc.
- CRISPR THERAPEUTICS
- Editas Medicine
- Mirus Bio LLC
Competitive Landscape
The global CRISPR and CRISPR-associated (Cas) genes market is relatively consolidated, with only a few prominent competitors. OriGene Technologies, Inc., Thermo Fisher Scientific, Takara Bio Inc, Horizon Discovery Ltd., Addgene, Merck KGaA, Caribou Biosciences, Inc., CRISPR THERAPEUTICS, Editas Medicine, and Mirus Bio LLC are some of the key companies in the market.

Table Of Content
1. Executive Summary
2. Assumptions and Acronyms Used
3. Research Methodology
4. CRISPR & Cas Genes Market Overview
4.1. Introduction
4.1.1. Market Taxonomy
4.1.2. Market Definition
4.2. Macro-Economic Factors
4.2.1. Industry Outlook
4.3. CRISPR & Cas Genes Market Dynamics
4.3.1. Market Drivers
4.3.2. Market Restraints
4.3.3. Opportunity
4.3.4. Market Trends
4.4. CRISPR & Cas Genes Market - Supply Chain
4.5. Global CRISPR & Cas Genes Market Forecast
4.5.1. CRISPR & Cas Genes Market Size (US$ Mn) and Y-o-Y Growth
4.5.2. CRISPR & Cas Genes Market Size (000’ Units) and Y-o-Y Growth
4.5.3. CRISPR & Cas Genes Market Absolute $ Opportunity
5. Global CRISPR & Cas Genes Market Analysis and Forecast by Applications
5.1. Market Trends
5.2. Introduction
5.2.1. Basis Point Share (BPS) Analysis by Applications
5.2.2. Y-o-Y Growth Projections by Applications
5.3. CRISPR & Cas Genes Market Size and Volume Forecast by Applications
5.3.1. Genome Engineering
5.3.2.
Disease Models
5.3.3.
Functional Genomics
5.3.4.
Others
5.4. Absolute $ Opportunity Assessment by Applications
5.5. Market Attractiveness/Growth Potential Analysis by Applications
6. Global CRISPR & Cas Genes Market Analysis and Forecast by End Users
6.1. Market Trends
6.2. Introduction
6.2.1. Basis Point Share (BPS) Analysis by End Users
6.2.2. Y-o-Y Growth Projections by End Users
6.3. CRISPR & Cas Genes Market Size and Volume Forecast by End Users
6.3.1. Biotechnology & Pharmaceutical Companies
6.3.2.
Academics & Government Research Institutes
6.3.3.
Contract Research Organizations
6.4. Absolute $ Opportunity Assessment by End Users
6.5. Market Attractiveness/Growth Potential Analysis by End Users
7. Global CRISPR & Cas Genes Market Analysis and Forecast by Region
7.1. Market Trends
7.2. Introduction
7.2.1. Basis Point Share (BPS) Analysis by Region
7.2.2. Y-o-Y Growth Projections by Region
7.3. CRISPR & Cas Genes Market Size and Volume Forecast by Region
7.3.1. North America
7.3.2. Latin America
7.3.3. Europe
7.3.4. Asia Pacific
7.3.5. Middle East and Africa (MEA)
7.4. Absolute $ Opportunity Assessment by Region
7.5. Market Attractiveness/Growth Potential Analysis by Region
7.6. Global CRISPR & Cas Genes Demand Share Forecast, 2019-2026
8. North America CRISPR & Cas Genes Market Analysis and Forecast
8.1. Introduction
8.1.1. Basis Point Share (BPS) Analysis by Country
8.1.2. Y-o-Y Growth Projections by Country
8.2. North America CRISPR & Cas Genes Market Size and Volume Forecast by Country
8.2.1. U.S.
8.2.2. Canada
8.3. Absolute $ Opportunity Assessment by Country
8.4. North America CRISPR & Cas Genes Market Size and Volume Forecast by Applications
8.4.1. Genome Engineering
8.4.2.
Disease Models
8.4.3.
Functional Genomics
8.4.4.
Others
8.5. Basis Point Share (BPS) Analysis by Applications
8.6. Y-o-Y Growth Projections by Applications
8.7. North America CRISPR & Cas Genes Market Size and Volume Forecast by End Users
8.7.1. Biotechnology & Pharmaceutical Companies
8.7.2.
Academics & Government Research Institutes
8.7.3.
Contract Research Organizations
8.8. Basis Point Share (BPS) Analysis by End Users
8.9. Y-o-Y Growth Projections by End Users
8.10. Market Attractiveness/Growth Potential Analysis
8.10.1. By Country
8.10.2. By Product Type
8.10.3. By Application
8.11. North America CRISPR & Cas Genes Demand Share Forecast, 2019-2026
9. Latin America CRISPR & Cas Genes Market Analysis and Forecast
9.1. Introduction
9.1.1. Basis Point Share (BPS) Analysis by Country
9.1.2. Y-o-Y Growth Projections by Country
9.1.3. Latin America Average Pricing Analysis
9.2. Latin America CRISPR & Cas Genes Market Size and Volume Forecast by Country
9.2.1. Brazil
9.2.2. Mexico
9.2.3. Rest of Latin America
9.3. Absolute $ Opportunity Assessment by Country
9.4. Latin America CRISPR & Cas Genes Market Size and Volume Forecast by Applications
9.4.1. Genome Engineering
9.4.2.
Disease Models
9.4.3.
Functional Genomics
9.4.4.
Others
9.5. Basis Point Share (BPS) Analysis by Applications
9.6. Y-o-Y Growth Projections by Applications
9.7. Latin America CRISPR & Cas Genes Market Size and Volume Forecast by End Users
9.7.1. Biotechnology & Pharmaceutical Companies
9.7.2.
Academics & Government Research Institutes
9.7.3.
Contract Research Organizations
9.8. Basis Point Share (BPS) Analysis by End Users
9.9. Y-o-Y Growth Projections by End Users
9.10. Market Attractiveness/Growth Potential Analysis
9.10.1. By Country
9.10.2. By Product Type
9.10.3. By Application
9.11. Latin America CRISPR & Cas Genes Demand Share Forecast, 2019-2026
10. Europe CRISPR & Cas Genes Market Analysis and Forecast
10.1. Introduction
10.1.1. Basis Point Share (BPS) Analysis by Country
10.1.2. Y-o-Y Growth Projections by Country
10.1.3. Europe Average Pricing Analysis
10.2. Europe CRISPR & Cas Genes Market Size and Volume Forecast by Country
10.2.1. Germany
10.2.2. France
10.2.3. Italy
10.2.4. U.K.
10.2.5. Spain
10.2.6. Russia
10.2.7. Rest of Europe
10.3. Absolute $ Opportunity Assessment by Country
10.4. Europe CRISPR & Cas Genes Market Size and Volume Forecast by Applications
10.4.1. Genome Engineering
10.4.2.
Disease Models
10.4.3.
Functional Genomics
10.4.4.
Others
10.5. Basis Point Share (BPS) Analysis by Applications
10.6. Y-o-Y Growth Projections by Applications
10.7. Europe CRISPR & Cas Genes Market Size and Volume Forecast by End Users
10.7.1. Biotechnology & Pharmaceutical Companies
10.7.2.
Academics & Government Research Institutes
10.7.3.
Contract Research Organizations
10.8. Basis Point Share (BPS) Analysis by End Users
10.9. Y-o-Y Growth Projections by End Users
10.10. Market Attractiveness/Growth Potential Analysis
10.10.1. By Country
10.10.2. By Product Type
10.10.3. By Application
10.11. Europe CRISPR & Cas Genes Demand Share Forecast, 2019-2026
11. Asia Pacific CRISPR & Cas Genes Market Analysis and Forecast
11.1. Introduction
11.1.1. Basis Point Share (BPS) Analysis by Country
11.1.2. Y-o-Y Growth Projections by Country
11.1.3. Asia Pacific Average Pricing Analysis
11.2. Asia Pacific CRISPR & Cas Genes Market Size and Volume Forecast by Country
11.2.1. China
11.2.2. Japan
11.2.3. South Korea
11.2.4. India
11.2.5. Australia
11.2.6. Rest of Asia Pacific (APAC)
11.3. Absolute $ Opportunity Assessment by Country
11.4. Asia Pacific CRISPR & Cas Genes Market Size and Volume Forecast by Applications
11.4.1. Genome Engineering
11.4.2.
Disease Models
11.4.3.
Functional Genomics
11.4.4.
Others
11.5. Basis Point Share (BPS) Analysis by Applications
11.6. Y-o-Y Growth Projections by Applications
11.7. Asia Pacific CRISPR & Cas Genes Market Size and Volume Forecast by End Users
11.7.1. Biotechnology & Pharmaceutical Companies
11.7.2.
Academics & Government Research Institutes
11.7.3.
Contract Research Organizations
11.8. Basis Point Share (BPS) Analysis by End Users
11.9. Y-o-Y Growth Projections by End Users
11.10. Market Attractiveness/Growth Potential Analysis
11.10.1. By Country
11.10.2. By Product Type
11.10.3. By Application
11.11. Asia Pacific CRISPR & Cas Genes Demand Share Forecast, 2019-2026
12. Middle East & Africa CRISPR & Cas Genes Market Analysis and Forecast
12.1. Introduction
12.1.1. Basis Point Share (BPS) Analysis by Country
12.1.2. Y-o-Y Growth Projections by Country
12.1.3. Middle East & Africa Average Pricing Analysis
12.2. Middle East & Africa CRISPR & Cas Genes Market Size and Volume Forecast by Country
12.2.1. Saudi Arabia
12.2.2. South Africa
12.2.3. UAE
12.2.4. Rest of Middle East & Africa (MEA)
12.3. Absolute $ Opportunity Assessment by Country
12.4. Middle East & Africa CRISPR & Cas Genes Market Size and Volume Forecast by Applications
12.4.1. Genome Engineering
12.4.2.
Disease Models
12.4.3.
Functional Genomics
12.4.4.
Others
12.5. Basis Point Share (BPS) Analysis by Applications
12.6. Y-o-Y Growth Projections by Applications
12.7. Middle East & Africa CRISPR & Cas Genes Market Size and Volume Forecast by End Users
12.7.1. Biotechnology & Pharmaceutical Companies
12.7.2.
Academics & Government Research Institutes
12.7.3.
Contract Research Organizations
12.8. Basis Point Share (BPS) Analysis by End Users
12.9. Y-o-Y Growth Projections by End Users
12.10. Market Attractiveness/Growth Potential Analysis
12.10.1. By Country
12.10.2. By Product Type
12.10.3. By Application
12.11. Middle East & Africa CRISPR & Cas Genes Demand Share Forecast, 2019-2026
13. Competition Landscape
13.1. Global CRISPR & Cas Genes Market: Market Share Analysis
13.2. CRISPR & Cas Genes Distributors and Customers
13.3. CRISPR & Cas Genes Market: Competitive Dashboard
13.4. Company Profiles (Details: Overview, Financials, Developments, Strategy)
13.4.1. OriGene Technologies, Inc.
13.4.2.
Thermo Fisher Scientific
13.4.3.
Takara Bio Inc
13.4.4.
Horizon Discovery Ltd.
13.4.5.
Addgene
13.4.6.
Merck KGaA
13.4.7.
Caribou Biosciences, Inc.