Cell Isolation Market Size, Share & Growth | Forecast 2031

Report Description

Cell Isolation Market Outlook 2031

The global cell isolation market size was USD 5.2 Billion in 2022 and is likely to reach USD 14.54 Billion by 2031, expanding at a CAGR of 12.1 % during, 2023–2031. The market growth is attributed to the rising government support for cell-based research, the rising prevalence of infectious and chronic diseases, and the growing emphasis on technical improvements and customized therapy.

Rising prevalence of infectious and chronic diseases such as cancer, diabetes, obesity, and others is anticipated to fuel the market growth. These diseases drive the demand for clinical trials and research, which require cell separation products. Pharmaceutical companies use cell isolation techniques to develop drugs and contribute to innovation.

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The stem cell is a crucial cell therapy in the development of regenerative medicine and is used for the replacement of organs or tissues. It requires a high number of clinical trials further, propelling the market. Rising technological advances in cell isolation methods are anticipated to fuel the market.

The term cell isolation or cell separation involves the extraction of desired cells while maintaining their integrity, viability, and functional properties by using different techniques. Growing advancements in this technology are enhancing market players to innovate in cell isolation methods. For instance,

• In October 2021, Akadeum Life Sciences generated over USD 17.5 million through a Series B business financing funding round, which was led by Arboretum Ventures. The startup plans to utilize this funding for the global commercializing of a microbubble-based separation platform with various applications including diagnosis and research on cell therapy.

The research report finds that the COVID-19 pandemic propelled the cell isolation market. It generated the need for research and diagnostics to understand the virus and its impact and transmission to the human body. Several pharmaceutical and biotech companies were engaged to create innovative treatments, vaccines, and test kits to cure the disease. These factors are anticipated to increase the demand for cell separation technologies.

Artificial Intelligence Impact on Cell Isolation

Artificial Intelligence (AI) has propelled the cell isolation market. AI is used to address complicated errors that occur in regenerative medicine. AI in stem cell therapy provides significant benefits to healthcare such as determining the bioefficacy, functionality, viability, and biosafety of stem cells and further the selection of appropriate patients.

For instance, in flow cytometry, AI algorithms analyze large datasets of cell populations more efficiently than traditional methods. These algorithms accurately sort and identify specific cell types. For instance,

• As per a published report on February 03, 2023, a research team from Toyohashi University of Technology’s Department of Mechanical Engineering and Electronics, developed a machine-learning (ML) model that accurately detects isolated cells. The ML model identifies single cells in microscopic images easing the human burden of finding out single cell.

Cell Isolation Market Dynamics

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Major Drivers

Increasing R&D processes in the biotechnology and pharmaceutical industries are expected to fuel the cell isolation market. Increasing development in tissue engineering or regenerative medicines, due to the rise in chronic diseases worldwide is expected to accelerate the use of cell isolation technology.

Furthermore, rising government funding for cell-based research and the rising number of patients suffering from infectious diseases is fueling the market. For instance,

• In April 2022, Levitas Bio, Inc., launched the LeviCell EOS System, their next-generation platform for cell separation, sample processing, and characterization. The new product enables a targeted selection of viable cells and has a relatively higher throughput than the company's existing products.

Existing Restraints

Rising concerns of safety & ethical issues are expected to hinder the market growth. The isolation of embryonic stem cells involves the destruction of embryos. This raises the concern of the destruction of human life, as some consider the embryo a potential human being. The embryonic stem cells form teratomas, which are tumors containing cells from three germ layers.

Lack of technically skilled technicians is expected to restrain the market. If the transplantation of embryonic stem cells to the patient is done without proper screening causes harm and forms tumors in the patient. Thus, these factors are anticipated to hamper the market.

Emerging Opportunities

Rising investments in the development and adoption of advanced technologies such as flow cytometry, microfluidics, and magnetic cell separation are expected to create lucrative opportunities in the market. This improves the efficiency and accuracy of cell isolation processes and makes the technology affordable and accessible in the market.

Scope of Cell Isolation Market Report

The market report includes an assessment of the market trends, segments, and regional markets. Overview and dynamics have also been included in the report.

Cell Isolation Market Segment Insights

Cell Type Segment Analysis

Based on cell type, the cell isolation market is bifurcated into human cells and animal cells. The human cells segment is further divided into stem cells and differentiated cells.

The animal cell segment held the largest revenue share in 2022 and is expected to expand at a significant growth rate during the projection period. The growth of the segment is attributed to the increased focus of government, private, and healthcare companies on new drug discoveries and developments.

The human cell segment is anticipated to hold a major share of the market in the forecast period, owing to the increasing focus on research on diverse applications of isolated human cells in diseases such as cancer, development in the biopharmaceutical industry, and clinical trials. Additionally, promising reimbursement policies for personalized medicine in emerging countries are driving the demand for cell isolation.

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Cell Source Segment Analysis

On the basis of cell source, the global market is segregated into adipose tissue, embryonic stem cells, bone marrow, and others. The bone marrow segment holds the largest revenue share of the market in 2022 and is projected to register a considerable CAGR during the forecast period, owing to growing cancer cases.

Bone marrow is a vital part of the human hematopoietic system. Bone marrow is a soft and spongy tissue found in certain bones of the body and plays a vital role in the production of immune cells and blood cells. Bone marrow is used in hematological malignancies, which involves the treatment and diagnosis of cancers. Rising incidences of cancer are further likely to propel the segment.

Product Segment Analysis

On the basis of product, the cell isolation market is segmented into consumables and instruments. The consumables segment is divided into reagents, kits, media & sera, beads, and disposables. The instruments segment is sub-segmented into magnetic-activated cell separator systems, flow cytometers, centrifuges, and filtration systems.

The consumable segment dominated the market and generated the largest revenue share, owing to repeated purchases of consumables. Additionally, increasing investments in research by biopharmaceutical and pharmaceutical companies for the development of advanced biologics are driving the segment.

The instrument segment is expected to register a robust growth rate during the forecast period, due to various product advancements. Technological advancements in instruments provide effectual cell separation in therapeutic applications, research, and diagnostics.

Technique Segment Analysis

Based on technique, the cell isolation market is trifurcated into filtration-based cell isolation, surface marker-based cell isolation, and centrifugation-based cell isolation. The centrifugation-based cell isolation segment dominates the market, owing to the extensive use of this technique by biopharmaceutical companies, research laboratories, academic institutes, and biotechnology. Centrifugation is a crucial step in the cell separation process.

The surface marker-based cell isolation segment is expected to expand at a significant growth rate during the projection period. The growth of the segment is attributed to the increasing investments in product advancements and infrastructure by companies. Manufacturers are using advanced surface markers to achieve a superior quality of end product.

Application Segment Analysis

On the basis of application, the global market is segregated into stem cell research, biomolecular isolation, in vitro diagnostics, cancer research, tissue regeneration, and therapeutics. The biomolecular isolation segment holds a dominant share of the market and is anticipated to grow at a rapid pace in the forecast period, owing to rising government funding for new drug development and increasing focus on biopharmaceuticals such as recombinant proteins, biosimilar, and monoclonal antibodies.

The cancer research segment is projected to register a considerable CAGR during the projected period, owing to increasing investments in cell-based research companies and laboratories. Several private and public organizations are investing in cancer research, owing to the growing incidences of cancer, which is driving the demand for cell isolation solutions.

Additionally, the advent of precision medicine for cancer treatment is expected to augment the market. For instance,

• On April 14, 2022, as per the report by the Netherlands Cancer Institute, the National Growth Funds invested EU 325 million in the Oncode-PACT plan. This investment accelerated the preclinical development process of cancer drugs. With this investment, it is expected to improve cancer patient's quality of life and the economic future of the country.

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End-user Segment Analysis

On the basis of end-user, the cell isolation market is classified as cell banks, biotechnology & biopharmaceutical companies, research laboratories & institutes, and hospitals & diagnostic laboratories. The biotechnology & biopharmaceutical companies segment held a dominant share of the market in 2022.

The growth of the segment is attributed to the increasing R&D investment by these companies to develop novel products. The research & development activities include advancements of new generation therapeutics that require cell-separation techniques.

The research laboratories & institutes segment is expected to register a robust growth rate during the forecast period, owing to increasing research activities by research institutions for the development of novel therapies in neuroscience and oncology. Rising number of research institutes & laboratories worldwide is anticipated to be a major factor driving the segment. For instance,

• According to a report released by Curate Biosciences on April 6, 2022, the Beckman Research Institute of City of Hope, one of the leading cancer treatment and research institutes, intends to incorporate its technology into its operations for producing investigational CAR-T cell immunotherapy.

Regional Outlook

In terms of region, the global cell isolation market is classified as Asia Pacific, North America, Latin America, Europe, and Middle East & Africa. North America dominated the global market, generating the highest revenue in 2022.

The market in the region is expected to grow in the coming years due to the adoption of technologically advanced solutions and the presence of established biotech & pharmaceutical industries.

Extensive research activities by research institutes in cell therapies have generated a huge demand for cell separation solutions. Furthermore, the high prevalence of infectious and chronic diseases including COVID-19, has increased focus on clinical and research applications in cell isolation solutions. For instance,

• As per a published report on April 12, 2023, the US Government is spending USD 5 billion in collaboration with the private sector to hasten the development of new COVID-19 vaccines.

The market in Asia Pacific is expected to generate a large revenue in the coming years, owing to the growing biotechnological and pharmaceutical industries in the emerging economies. Rising healthcare expenditure and increasing market penetration of global players are projected to fuel the market in the assessment period.

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