According to a recent market study published by Growth Market Reports, titled, “Global Chloroacetonitrile Market by Purity (Below 99% and 99% & Above), by Application (Organic Synthesis Intermediate, Pharmaceutical Intermediate, Fumigant, and Others), By Distribution Channel (Direct Sales through Manufacturers and Wholesalers/Distributors), and by Region (North America, Asia Pacific, Europe, Latin America, and Middle East & Africa) Size, Share, Trends, and Opportunity Analysis, 2016-2031”, the market was valued at USD 20,634.1 Thousand in 2022 and is expected to increase at a growth rate of 6.4% by the year 2031. The global chloroacetonitrile held market volume XX Tons in 2022 and is expected to increase at a growth rate of XX% by the year 2031.

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Chloroacetonitrile, also known as cyanide chloromethane, with a chemical formula being ClCH2CN and the molecular weight being 75.50. It is a colorless and fuming liquid with the melting point being 38 and boiling point 126~127 . It is soluble in ether, alcohol, and hydrocarbons, although insoluble in water. It is highly toxic.

Chloroacetonitrile is obtained through the dehydration of chloroacetamide under the action of phosphorus pentoxide, the reaction between excess amount of acetonitrile with chlorine at 460 , or by introducing ammonia gas into the ether solution of dichloro-acetylene.

As per Growth Market Reports industry analyst Riddhesh Dani, the “Global Chloroacetonitrile Market” is anticipated to witness significant growth during the forecast period 2023-2031. Chloroacetonitrile is used as organic intermediate for insecticide manufacturing and used as an intermediate for drugs such as guanethidine. Increasing demand for pharmaceuticals and agrochemicals is expected to create demand for chloroacetonitrile, and thus, propelling the market. Technological advancements in production and cost reduction initiatives are expected to provide new opportunities to the manufacturers.

Chloroacetonitrile is used to prepare fumigant, which is a kind of pesticides and its volatile vapor is applied to poison and kill pests. It reacts with water, steam, strong acids, or acid fumes to produce toxic vapors of hydrogen chloride. When heated to decomposition, it emits highly toxic fumes of hydrogen cyanide and hydrogen chloride. This vapor causes dizziness or suffocation.

Chloroacetonitrile is extensively used in the chemical industry as organic synthesis intermediate. It is used in synthesis of fenoxycarb, which is used as an insecticide. It is also used as an eluent additive in thermospray liquid chromatography/mass spectrometry. Further, it is used to prepare polysubstituted pyridobenzimidazole by reacting with another reactant such as malononitrile, aromatic aldehyde, and pyridine.

The primary and secondary research methodology is used for keen observation and study of Chloroacetonitrile. The primary research methodology involves commercial agreements made with the primary respondents and consulting partners to extract critical information pertaining to the syndicated as well as consulting projects. Primary interviews were conducted with the stakeholders across industry verticals at regular intervals in line with the ongoing studies and to keep ourselves abreast with the latest market trends & developments. Validation of the estimated market size and current & future trends done by the key opinion leaders (KOLs). These KOLs are the CXO level people from leading companies in the industry and possess experience of around 10-20 years in the industry. On the other hand, the secondary research methodology involves exhaustive desk research undertaken to understand the prevailing market trends & dynamics, market competition, customer insights, and other KPIs. Company websites, their SEC filings, annual reports, broker & financial reports, and investor presentations are scanned for understanding the competitive scenario, details, developments, and the overall competitive landscape. Regional government and statistical databases were analyzed for macro & microanalysis. Research publications and paid data are referred to obtain and validate the market estimations, budget, expenditure, and other statistical insights.

The outbreak of coronavirus disease in 2019 (COVID-19) restrained the global economy, created global interdependence, and challenged the governments of various nations. The pandemic raised concerns among economies and businesses by shifting focus to the online supply of consumer electronic gadgets & automotive components and creating manufacturing issues.

In January 2020, the WHO labeled the COVID-19 outbreak as a public health emergency of global concern and proclaimed it a global pandemic in March 2020. This deadly virus has become one of the biggest pandemics in the human history. The COVID-19 outbreak is a public health emergency that affected almost every industry. The long-term effects of the pandemic are expected to affect the growth of various industries during the forecast period, especially across Eastern Europe, European Union, the US, and Eastern & Central Asia.

As of February 13, 2023, this pandemic had infected over 678,724,789 people, and over 6,791,202 people died from the disease. COVID-19 cases have been registered in more than 231 countries and territories. Many countries are economically weak, while others have poor healthcare systems that affect the economy and life of people.

Key Takeaways from the Study:

  • The key players in the market include Thermo Fisher Scientific, Hefei Home Sunshine Pharmaceuticals., Merck KGaA, Clearsynth, ANNEXE CHEM PVT LTD, Ami Organics., Central Drug House, Otto Chemie Pvt. Ltd., TNJ Chemicals, NINGBO INNO PHARMCHEM CO.,LTD. , Shanghai Sunwise Chemical Co., and TCI Chemicals.

  • Players like Thermo Fisher Scientific and Merck KGaA have a significant market share in global chloroacetonitrile market.

  • On the basis of application, the global chloroacetonitrile market is divided into organic synthesis intermediate, pharmaceutical intermediate, fumigant, and others. The others segment includes applications, such as extraction solvents and laboratory reagent. The pharmaceutical intermediate segment holds a significant market share, owing to the extensive use of chloroacetonitrile for synthesis of pharmaceuticals.

  • Chloroacetonitrile has several applications in the agrochemical industry. It is used in manufacturing herbicides to control undesirable vegetation and control pests. It is used in synthesis of insecticide fenoxycarb. It is also used in industrial processing as an organic intermediate in the synthesis of the cardiovascular drug, guanethidine.

  • Asia Pacific region holds significant market share in global chloroacetonitrile market. Growth of the market in Asia Pacific region is driven by the growing demand for chloroacetonitrile, mainly from the pharmaceutical industry. The market in Asia Pacific is expected to expand at a lucrative CAGR, owing to rising industrial production of chloroacetonitrile and increasing demand for chloroacetonitrile from the pharmaceutical industry.

Report Scope:

Report Metric


Market Value in 2022

USD 20,634.1 Thousand

Market Volume in 2022

XX Tons

Market Growth Rate (from 2023 to 2031)

6.4 %

Historical Data

2016 & 2021

Base Year


Forecast Period

2023 – 2031

Units Considered

Value (USD Thousand)


Volume (Tons)

Market Segments

By Purity (Below 99% and 99% & Above), By Application (Organic Synthesis Intermediate, Pharmaceutical Intermediate, Fumigant, and Others), and By Distribution Channel (Direct Sales through Manufacturers and Distributors/wholesalers)

Key Companies Profiled

Thermo Fisher Scientific, Hefei Home Sunshine Pharmaceuticals., Merck KGaA, Clearsynth, ANNEXE CHEM PVT LTD, Ami Organics., Central Drug House, Otto Chemie Pvt. Ltd., TNJ Chemicals, NINGBO INNO PHARMCHEM CO.,LTD. , Shanghai Sunwise Chemical Co., and TCI Chemicals

Customization Scope

Report customization available on request

Pricing and Purchase Options

Avail tailor-made purchase options to meet your research requirements.


Target Audience:

  • Supply-side: Raw Material Suppliers and Manufactures

  • Demand Side: Pharmaceuticals Companies, Agrochemical Manufacturers

  • Regulatory Side: Concerned Government Authorities and Other Regulatory Bodies